SCHEMBL7597904

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL9999755	1.00	BACE1 (0.38)	BACE1RARBPDE3BPDE3AS1PR1
	SCHEMBL13253176	0.93	RARB (0.39)	BACE1RARBPDE3BPDE3AS1PR1
	SCHEMBL13253197	0.93	BACE1 (0.42)	BACE1RARBPDE3BPDE3AS1PR1
	SCHEMBL18540027	0.93	TAAR1 (0.39)	RARBTAAR1RARARARGKIF11
	SCHEMBL6059171	0.89	BACE1 (0.38)	BACE1RARBPDE3BPDE3AS1PR1
	SCHEMBL16789601	0.89	RARB (0.43)	RARBS1PR1TAAR1RARARARG
	SCHEMBL9999856	0.89	RARB (0.40)	RARBS1PR1TAAR1RARARARG
	SCHEMBL15180193	0.89	RARB (0.43)	RARBS1PR1TAAR1RARARARG
	SCHEMBL12760546	0.89	RARB (0.40)	RARBS1PR1TAAR1RARARARG
	SCHEMBL20219122	0.87	TAAR1 (0.42)	RARBPDE3BPDE3ATAAR1CYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 196 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.