SCHEMBL9999987

SCHEMBL9999987

O=C(O)CNC(=O)C(=O)NCC(=O)O

nearest known ligand 0.62

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
EGLN1 Q9GZT9 2/20 0.62
PLA2G2A P14555 1/20 0.48
MAPT P10636 2/20 0.46
ALDH1A1 P00352 2/20 0.46
LMNA P02545 1/20 0.46
PTGS2 P35354 1/20 0.46
TDP1 Q9NUW8 1/20 0.46
LDHA P00338 1/20 0.44
SRR Q9GZT4 1/20 0.44
CTH P32929 1/20 0.43
APEX1 P27695 1/20 0.41
MME P08473 4/20 0.41
ECE1 P42892 1/20 0.39
KDM4E B2RXH2 1/20 0.39
HIF1A Q16665 1/20 0.39
SLC22A6 Q4U2R8 1/20 0.39
SLC22A8 Q8TCC7 1/20 0.39
ABAT P80404 1/20 0.38
ACE P12821 1/20 0.38
CPA1 P15085 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
N-Oxalylglycine SCHEMBL435820 0.87 EGLN1 (0.56) EGLN1PLA2G2AMAPTALDH1A1LMNA
SCHEMBL13401875 0.86 EGLN1 (0.50) EGLN1PLA2G2AMAPTALDH1A1LMNA
SCHEMBL7457741 0.82 EGLN1 (0.52) EGLN1PLA2G2AMAPTALDH1A1LMNA
SCHEMBL10080192 0.82 EGLN1 (0.52) EGLN1PLA2G2AMAPTALDH1A1LMNA
SCHEMBL597184 0.82 EGLN1 (0.58) EGLN1PLA2G2AMAPTALDH1A1LMNA
SCHEMBL6910661 0.82 EGLN1 (0.52) EGLN1PLA2G2AMAPTALDH1A1LMNA
SCHEMBL11140818 0.80
SCHEMBL29199464 0.80 EGLN1 (0.61) EGLN1PLA2G2AMAPTALDH1A1LMNA
SCHEMBL4943507 0.80 EGLN1 (0.56) EGLN1PLA2G2AMAPTALDH1A1LMNA
SCHEMBL17373960 0.79 EGLN1 (0.48) EGLN1PLA2G2AMAPTALDH1A1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8663902-B2 Laser imaging DATALASE LTD (GB) 2014-03-04 US disclosed
US-8663902-B2 Laser imaging DATALASE LTD (GB) 2014-03-04 US disclosed
US-20120021363-A1 Co-Crystals and Their Use DATALASE LTD. (GB) 2012-01-26 US disclosed
US-20120021363-A1 Co-Crystals and Their Use DATALASE LTD. (GB) 2012-01-26 US disclosed
US-20120021362-A1 Laser Imaging DATALASE LTD. (GB) 2012-01-26 US disclosed
US-20120021362-A1 Laser Imaging DATALASE LTD. (GB) 2012-01-26 US disclosed
WO-2010112940-A1 LASER IMAGING DATALASE LTD. (GB) 2010-10-07 WO disclosed
WO-2010089595-A1 CO-CRYSTALS AND THEIR USE DATALASE LTD. (GB) 2010-08-12 WO disclosed