ABCE1

ATP-binding cassette sub-family E member 1 · P61221 · ABCE1 on Sugi Atlas →

0 patent compounds predicted against ABCE1, 0 high-confidence (nearest known ligand ≥ 0.5)

Top predicted compounds (top 20 by supporting neighbours, then confidence)

CompoundConfidenceSupporting neighbours

Clinical trials — most relevant to ABCE1 by text similarity (a relevance ranking, not an exhaustive list)

TrialPhaseStatus
BSEP Function Rescue During Childhood Inhereditary Cholestatic Diseases PHASE2/PHASE3WITHDRAWN
A Phase 2 Trial of SCO-101 in Combination With FOLFIRI for Patients With Metastatic Colorectal Cancer (mCRC) With Acquired Resistance to FOLFIRI PHASE1/PHASE2UNKNOWN
Everolimus (RAD001) for Children With Chemotherapy-Refractory Progressive or Recurrent Low-Grade Gliomas PHASE2COMPLETED
The Evaluation of the Drug R3R01 for the Excretion of Protein in the Urine in Patients With Diabetic Kidney Disease. PHASE2RECRUITING
A Study of ABC294640 Alone and in Combination With HCQ Sulfate in the Treatment of Advanced Cholangiocarcinoma PHASE2COMPLETED
Pamiparib in Fusion Positive, Reversion Negative High Grade Serous Ovarian Cancer or Carcinosarcoma With BRCA1/2 Gene Mutations If Progression on Substrate Poly ADP Ribose Polymerase Inhibitbor (PARPI) or Chemotherapy PHASE2WITHDRAWN
Influence of Ethnicity and ABCB1 Gene Polymorphism on the Pharmacokinetics of Azithromycin in Healthy Bangladeshi Volunteers PHASE1UNKNOWN
Indenoisoquinoline LMP744 in Adults With Relapsed Solid Tumors and Lymphomas PHASE1COMPLETED
Icotinib Hydrochloride in Treating Patients With Advanced Cancers PHASE1WITHDRAWN
Indenoisoquinoline LMP400 for Advanced Solid Tumors and Lymphomas PHASE1COMPLETED
Dinaciclib and Akt Inhibitor MK2206 in Treating Patients With Pancreatic Cancer That Cannot Be Removed by Surgery PHASE1COMPLETED
Efavirenz for Patients With Alzheimer's Disease PHASE1COMPLETED
Multidrug Resistance Genes in Patients With Acute Myeloid Leukemia nanACTIVE_NOT_RECRUITING
Bile Acids Metabolism and Genetic Mutation Profile in the Intrahepatic Cholestasis of Pregnacy in Indian Population nanRECRUITING
the Effect of ABCC2 Genetic Polymorphism on Neurotoxicity in Gastrointestinal Cancer Patients Receiving Oxaliplatin nanUNKNOWN
Ezetimibe Utilization Early After Acute Myocardial Infarction, EzAMI Trial nanRECRUITING
Hydroxychloroquin (HCQ) in chILD of Genetic Defect nanCOMPLETED
Coproporphyrine Isomers and Methotrexate Elimination nanCOMPLETED
Placental Transfer of Tenofovir nanCOMPLETED
Genetic Causes and Clinical Features of Childhood Interstitial Lung Diseases in China nanCOMPLETED
Ginger and Plasma Cholesterol Efflux Capacity nanCOMPLETED
Role of Gene Variation in Effectiveness of Gleevec Treatment nanCOMPLETED
Evaluation of Pharmacogenetic Factors Affecting Fentanyl Requirements for Postoperative Pain Control nanCOMPLETED
High-Density Lipoprotein (HDL) Treatment Study nanCOMPLETED
The Genetic, Protein, and Lipid Basis of Variation in Cholesterol Efflux nanCOMPLETED
Role of the ATP7A Transporter in Ovarian Cancer nanCOMPLETED
The Association of SAA With Apolipoprotein B Affects Cardiovascular Risk nanCOMPLETED
Analysis of Genes That Predispose People to Develop High Blood Pressure nanCOMPLETED
Function and Imaging Assessments for G1961E-associated Stargardt Disease nanACTIVE_NOT_RECRUITING
Genetic Determinants:Low HDL, High Triglycerides, Obesity nanCOMPLETED

Related proteins — ESM-2 sequence neighbours (a ABCE1 binder may also engage these)

ProteinNameSimilarity
P61222 1.000 P61222 →
Q8LPJ4 0.985 Q8LPJ4 →
G0SEV9 0.980 G0SEV9 →
Q9LID6 0.967 Q9LID6 →
Q9VSS1 0.959 Q9VSS1 →
Q03195 0.958 Q03195 →
Q24208 0.958 Q24208 →
Q7YQM0 0.956 Q7YQM0 →
P50396 0.956 P50396 →
Q60LW7 0.955 Q60LW7 →
GDI1 Rab GDP dissociation inhibitor alpha 0.955 landscape →
O97556 0.954 O97556 →
P60028 0.953 P60028 →
Q9VQZ6 0.952 Q9VQZ6 →
P50398 0.951 P50398 →
Q8HXX7 0.951 Q8HXX7 →
A2VE01 0.951 A2VE01 →
Q6Q7J2 0.950 Q6Q7J2 →
P21856 0.950 P21856 →
O97555 0.950 O97555 →
Q93ZR1 0.950 Q93ZR1 →
Q6UPE1 0.949 Q6UPE1 →
P35615 0.949 P35615 →
P55931 0.949 P55931 →
Q5RDD3 0.949 Q5RDD3 →
Q5ZJL4 0.949 Q5ZJL4 →
O55029 0.948 O55029 →
Q2KIG0 0.947 Q2KIG0 →
Q9GR88 0.947 Q9GR88 →
Q23651 0.947 Q23651 →