ABHD10 — patent landscape

Top predicted compounds (top 20 by supporting neighbours, then confidence)

Compound	Confidence	Supporting neighbours
SCHEMBL15321687	1.00	2/20
SCHEMBL15326055	1.00	2/20
SCHEMBL15326048	0.74	2/20
SCHEMBL15326056	0.69	2/20
SCHEMBL15326063	0.66	2/20
SCHEMBL15326051	0.65	2/20
SCHEMBL15326053	0.52	2/20
SCHEMBL31556611	0.88	1/20
SCHEMBL17396592	0.75	1/20
SCHEMBL17396593	0.75	1/20
SCHEMBL17414016	0.72	1/20
SCHEMBL18836259	0.72	1/20
SCHEMBL18836260	0.72	1/20
SCHEMBL18854661	0.72	1/20
SCHEMBL24180211	0.72	1/20
SCHEMBL17414107	0.71	1/20
SCHEMBL18836092	0.71	1/20
SCHEMBL29532250	0.71	1/20
Rocagloic Acid (SCHEMBL750035)	0.69	1/20
Rocagloic Acid (SCHEMBL752143)	0.69	1/20

Clinical trials — most relevant to ABHD10 by text similarity (a relevance ranking, not an exhaustive list)

Trial	Phase	Status
Cystagon to Treat Infantile Neuronal Ceroid Lipofuscinosis	PHASE4	COMPLETED
Betaine and Peroxisome Biogenesis Disorders	PHASE3	COMPLETED
The Effects of Coenzyme A Combined With Abiraterone on Patients With CRPC	PHASE1/PHASE2	UNKNOWN
Clinical Trial of High Dose CoQ10 in ALS	PHASE2	COMPLETED
ONC201 in Recurrent/Refractory Metastatic Breast Cancer and Advanced Endometrial Carcinoma	PHASE2	COMPLETED
A Study of Bezafibrate in Mitochondrial Myopathy	PHASE2	COMPLETED
Atorvastatin, L-Carnitine and Non-Alcoholic Steatohepatitis	PHASE2	UNKNOWN
Dynamics of Muscle Mitochondria in Type 2 Diabetes (DYNAMMO T2D)	EARLY_PHASE1	COMPLETED
Fatty Acid Oxidation Defects and Insulin Sensitivity	nan	COMPLETED
Tissue Sample Study for Mitochondrial Disorders	nan	ENROLLING_BY_INVITATION
MERC Proteins in Saliva and GCF in Periodontal Disease (ELISA Study)	nan	COMPLETED
Abnormalities in the Effects of Insulin and Exercise on Glucose- and Lipid Metabolism in Obesity and Type 2 Diabetes	nan	COMPLETED
Measuring Protein Turnover in Humans Across the Lifespan by Metabolic Labeling With Deuterium Oxide	nan	RECRUITING
Investigations Into ISCU Myopathy or Iron Sulfur Scaffold U Protein Myopathy	nan	COMPLETED
A Study Into the Underlying Biochemical Pathways Involved in Parkinson's Disease, Such as Mitochondrial (Cellular Powerhouse) Dysfunction	nan	COMPLETED
Identification of New Candidate Genes in Patients With Mitochondrial Disease by High Resolution Chromosome Analysis on DNA Chip	nan	COMPLETED
Dynamics of Muscle Mitochondria in Type 2 Diabetes Exercise	nan	COMPLETED
Mitochondrial Membrane Protein Neurodegeneration (MPAN)	nan	COMPLETED
The LD Lync Study - Natural History Study of Lipodystrophy Syndromes	nan	RECRUITING
A Prospective Study of the Disease Characteristics of Adult Patients With Long Chain Fatty Acid Oxidation Disorders	nan	COMPLETED
Heart and Muscle Metabolism in Barth Syndrome	nan	COMPLETED
North American Mitochondrial Disease Consortium Patient Registry and Biorepository (NAMDC)	nan	RECRUITING
Genomic Profiling of Mitochondrial Disease - Imaging Analysis for Precise Mitochondrial Medicine	nan	COMPLETED
Universal Rare Gene Study: A Registry and Natural History Study of Retinal Dystrophies Associated With Rare Disease-Causing Genetic Variants	nan	RECRUITING
Pathogenic Insights and Search for Biomarkers in RFC1-ataxia/CANVAS	nan	RECRUITING
GDF-15 as a Biomarker for Mitochondrial Disease	nan	COMPLETED
Effect of Short-Term Exercise Training on ATP Synthesis in Relatives of Type 2 Diabetic Humans	nan	COMPLETED
Skeletal Muscle Mitochondrial Abnormalities and the Metabolic Syndrome in PAH	nan	COMPLETED
Assessing the Role of Mitochondrial Dysfunction in Primary Progressive Multiple Sclerosis	nan	UNKNOWN
Exercise-mediated Rescue of Mitochondrial Dysfunctions Driving Insulin Resistance	nan	COMPLETED

Related proteins — ESM-2 sequence neighbours (a ABHD10 binder may also engage these)

Protein	Name	Similarity
Q5E9H9	—	1.000	Q5E9H9 →
Q5REX5	—	1.000	Q5REX5 →
Q5I0K5	—	1.000	Q5I0K5 →
Q6PE15	—	0.997	Q6PE15 →
Q7T0X7	—	0.969	Q7T0X7 →
Q90678	—	0.969	Q90678 →
A4IHY0	—	0.968	A4IHY0 →
Q8R164	—	0.968	Q8R164 →
P83006	—	0.964	P83006 →
Q8VE38	—	0.964	Q8VE38 →
Q58DM7	—	0.964	Q58DM7 →
Q8VDG7	—	0.963	Q8VDG7 →
Q96QE5	—	0.963	Q96QE5 →
Q5RJG7	—	0.963	Q5RJG7 →
O77480	—	0.962	O77480 →
A0JPF9	—	0.962	A0JPF9 →
P79106	—	0.962	P79106 →
E1BCH6	—	0.962	E1BCH6 →
Q99487	—	0.962	Q99487 →
Q9W758	—	0.961	Q9W758 →
P98192	—	0.961	P98192 →
Q5R4D2	—	0.961	Q5R4D2 →
Q5S6T3	—	0.961	Q5S6T3 →
Q6DJF8	—	0.961	Q6DJF8 →
Q94E75	—	0.961	Q94E75 →
A6QPR9	—	0.960	A6QPR9 →
Q566R0	—	0.960	Q566R0 →
Q5I0C5	—	0.960	Q5I0C5 →
Q9EPB5	—	0.959	Q9EPB5 →
A5A6K6	—	0.959	A5A6K6 →