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ADAM33

Disintegrin and metalloproteinase domain-containing protein 33 · Q9BZ11 · ADAM33 on Sugi Atlas →

1,840 patent compounds predicted against ADAM33, 1,619 high-confidence (nearest known ligand ≥ 0.5)

Top predicted compounds (top 20 by supporting neighbours, then confidence)

CompoundConfidenceSupporting neighbours
SCHEMBL995853 SCHEMBL995853 1.00 9/20
SCHEMBL995855 SCHEMBL995855 1.00 9/20
SCHEMBL996082 SCHEMBL996082 1.00 9/20
SCHEMBL996083 SCHEMBL996083 1.00 9/20
SCHEMBL996444 SCHEMBL996444 1.00 9/20
SCHEMBL996447 SCHEMBL996447 1.00 9/20
SCHEMBL997483 SCHEMBL997483 1.00 9/20
SCHEMBL997484 SCHEMBL997484 1.00 9/20
SCHEMBL997565 SCHEMBL997565 1.00 9/20
SCHEMBL997567 SCHEMBL997567 1.00 9/20
SCHEMBL998761 SCHEMBL998761 1.00 9/20
SCHEMBL998762 SCHEMBL998762 1.00 9/20
SCHEMBL996219 SCHEMBL996219 0.84 9/20
SCHEMBL996220 SCHEMBL996220 0.84 9/20
SCHEMBL998467 SCHEMBL998467 0.84 9/20
SCHEMBL998468 SCHEMBL998468 0.84 9/20
SCHEMBL998692 SCHEMBL998692 0.84 9/20
SCHEMBL998694 SCHEMBL998694 0.84 9/20
SCHEMBL996481 SCHEMBL996481 0.84 9/20
SCHEMBL996483 SCHEMBL996483 0.84 9/20

Clinical trials — most relevant to ADAM33 by text similarity (a relevance ranking, not an exhaustive list)

TrialPhaseStatus
Estimation of MMP-8 Levels in GCF and Serum and Its Correlation With Wound Healing and Clinical Outcomes After Coronally Advanced Flap and Subepithelial Connective Tissue Graft for Root Coverage in Recession Defects: A CLINICO-BIOCHEMICAL STUDY PHASE4SUSPENDED
Efficacy of Pioglitazone and Metformin on Cardiovascular Risk in Subjects With Insulin-Treated Type 2 Diabetes Mellitus. PHASE4COMPLETED
Clinical Trial With Aprotinin in the Acute Respiratory Distress Syndrome Treatment PHASE3NOT_YET_RECRUITING
Sputum Matrix Metalloproteinases (MMP) mRNA and Montelukast PHASE2COMPLETED
Tranexamic Acid (TXA) and Corona Virus 2019 (COVID19) in Inpatients PHASE2WITHDRAWN
A Study of Sorafenib in Patients With Chemonaive Metastatic Uveal Melanoma PHASE2UNKNOWN
The Role of Matrix Metalloproteinases (MMPs) in Orthodontic Tooth Movement PHASE1COMPLETED
Role of A Disintegrin and Metalloproteinase (ADAM) in Epithelial Dysfunction nanCOMPLETED
Evaluation of Different Serum Cartilage Biomarkers in the Acute Response to Walking and Cycling in Healthy Male Subjects nanAVAILABLE
Extracellular Matrix Remodeling of the Umbilical Cord and Placenta in Preeclampsia nanUNKNOWN
Apoptotic Changes in Gingiva Caused by Smoking nanCOMPLETED
Association Between Matrix Metalloproteinase-2 Gene Polymorphism rs243865 and Susceptibility to Cataract Development nanCOMPLETED
Peri-implantitis and MMP-8 nanCOMPLETED
Role of Extracellular Matrix in the Development of Airway Remodeling in Asthma nanUNKNOWN
Influence of Statins in Artery Aneurysms nanUNKNOWN
Apoptosis Markers in Aggressive Periodontitis nanCOMPLETED
Early Diagnosis and Prognosis of Postoperative Sepsis by Presepsin and Syndecan-1 nanUNKNOWN
Circulating Markers for Ischemic Heart Disease nanRECRUITING
Salivary Markers in Periodontal Disorders nanCOMPLETED
Correlation Between Serum Markers of Unstable Plaque and Virtual Histology of Unstable Plaque Visualized by IVUS nanCOMPLETED
Infection, Sepsis and Meningitis in Surinamese Neonates nanCOMPLETED
miRNA-452 in Patients With Preeclampsia and Its Correlation With MMP-9 nanCOMPLETED
Detection of Cancer-Specific Active Proteases in Blood Via Fluorescence nanWITHDRAWN
Role of Circulating MicroRNAs in Pathogenesis of Aneurysms of the Abdominal and Thoracic Aorta - Study Micro AAA nanUNKNOWN
Biomarkers in Post Thrombotic Syndrome nanCOMPLETED
Pharmacokinetics of Low Molecular Weight Heparin in Cancer Patients nanCOMPLETED
Disorders of the Acute Phase Response Following Trauma and Invasive Surgery nanENROLLING_BY_INVITATION
Study of Trans-tissular Migration of Macrophages Associated to Human Breast Cancer nanUNKNOWN
The Biologic Basis of Hernia Formation nanCOMPLETED
Biomarker Levels as A Predictor of Concussion Severity OUTcomes (BlacOut) nanCOMPLETED

Related proteins — ESM-2 sequence neighbours (a ADAM33 binder may also engage these)

ProteinNameSimilarity
Q923W9 — 0.986 Q923W9 →
Q6ZMM2 — 0.964 Q6ZMM2 →
Q63148 — 0.941 Q63148 →
Q9H2X0 — 0.941 Q9H2X0 →
Q9BZG2 — 0.939 Q9BZG2 →
Q9Z0E2 — 0.938 Q9Z0E2 →
Q9H1Z9 — 0.936 Q9H1Z9 →
O00587 — 0.935 O00587 →
Q32PI0 — 0.933 Q32PI0 →
Q5IS64 — 0.932 Q5IS64 →
Q5RF19 — 0.932 Q5RF19 →
O75610 — 0.930 O75610 →
Q9C0J1 — 0.930 Q9C0J1 →
Q9UP79 — 0.930 Q9UP79 →
Q14626 — 0.930 Q14626 →
O00292 — 0.929 O00292 →
O76076 — 0.928 O76076 →
Q64385 — 0.926 Q64385 →
Q99MF4 — 0.925 Q99MF4 →
Q5TM22 — 0.924 Q5TM22 →
O46547 — 0.924 O46547 →
Q9R1V4 — 0.924 Q9R1V4 →
Q8N9H8 — 0.924 Q8N9H8 →
Q8N135 — 0.924 Q8N135 →
Q06643 — 0.923 Q06643 →
O75078 — 0.923 O75078 →
Q9JHS6 — 0.923 Q9JHS6 →
Q7TNS7 — 0.923 Q7TNS7 →
Q9BQ83 — 0.923 Q9BQ83 →
D3YTS9 — 0.923 D3YTS9 →