AP1S1

AP-1 complex subunit sigma-1A · P61966 · AP1S1 on Sugi Atlas →

0 patent compounds predicted against AP1S1, 0 high-confidence (nearest known ligand ≥ 0.5)

Top predicted compounds (top 20 by supporting neighbours, then confidence)

CompoundConfidenceSupporting neighbours

Clinical trials — most relevant to AP1S1 by text similarity (a relevance ranking, not an exhaustive list)

TrialPhaseStatus
Clinical Evaluation of the Effect of Metformin in Sepsis PHASE3UNKNOWN
The Use of Inhaled Corticosteroids in the Treatment of Asthma is Children in the Emergency Room PHASE2/PHASE3COMPLETED
Melpida: Recombinant Adeno-associated Virus (serotype 9) Encoding a Codon Optimized Human AP4M1 Transgene (hAP4M1opt) PHASE1/PHASE2RECRUITING
A Study of Bezafibrate in Mitochondrial Myopathy PHASE2COMPLETED
Decitabine and Venetoclax Treatment as Maintenance Therapy in Patients Post Allograft Stem Cell Transplant PHASE1/PHASE2RECRUITING
Effect of Deferoxamine on Wound Healing Rate in Patients With Diabetes Foot Ulcers PHASE2NOT_YET_RECRUITING
Preliminary Study of Mycograb and Docetaxel in Advanced Breast Cancer PHASE1/PHASE2COMPLETED
A Study of APX3330 in Patients With Advanced Solid Tumors PHASE1COMPLETED
Temsirolimus and Sorafenib in Advanced Hepatocellular Carcinoma PHASE1COMPLETED
Risk Factors of Hepatocellular Carcinomas Developed on Non-fibrotic Liver: Case-control Study (NoFlic Study) nanCOMPLETED
Autophagy in Systemic Lupus Erythematosus nanUNKNOWN
Role of SF3B1 Mutation in Assessment of Acute and Chronic Lymphatic Leukemia nanNOT_YET_RECRUITING
Regulation of Lymphocyte Anti-tumor Response in Metastatic Patients Treated With the mTOR Inhibitor Everolimus nanCOMPLETED
Defective Atypical Protein Kinase C (PKC) Activation in Diabetes and Metabolic Syndrome nanCOMPLETED
Diagnosis of RSTS: Identification of the Acetylation Profiles as Epigenetic Markers for Assessing Causality of CREBBP and EP300 Variants. nanUNKNOWN
Effect of Protein on Endoplasmic Reticulum Stress nanNOT_YET_RECRUITING
Pigeon Peas (Cajanus Cajan) : a Natural Anti-inflammatory Facilitating Weight Loss in Obese Patients Returning to Sport? nanUNKNOWN
Evaluation of the Effect of Alpha Lipoic Acid on Radiation Induced Dermatitis in Breast Cancer Patients nanRECRUITING
Recombinant Interferon Alfa-2b in Treating Patients With Melanoma nanCOMPLETED
Genetic Risk Factors Associated With Antiphospholipid Antibody Syndrome nanRECRUITING
Shwachman Diamond Syndrome Registry and Study nanRECRUITING
MERC Proteins in Saliva and GCF in Periodontal Disease (ELISA Study) nanCOMPLETED
Immune Cell Response to Stimuli nanRECRUITING
Multi-level Molecular Profiling of High Acute Stress: a Clinical Study nanUNKNOWN
Bipolar Disorder Integrative Staging: Incorporating Biomarkers Into Progression Across Stages nanACTIVE_NOT_RECRUITING
Evaluation of the Predictive Effect of Inflammatory Markers in MI Patients nanUNKNOWN
Steroid Treatment of Idiopathic Nephrotic Syndrome nanCOMPLETED
Exploring the Genetics of Neuropathic Pain nanRECRUITING
JAK-STAT Signalling Pathway in Familial Myeloproliferative Disorders nanCOMPLETED
Genetics of Endocrine Tumours - Familial Isolated Pituitary Adenoma - FIPA nanRECRUITING

Related proteins — ESM-2 sequence neighbours (a AP1S1 binder may also engage these)

ProteinNameSimilarity
P61967 1.000 P61967 →
Q1JQ98 1.000 Q1JQ98 →
Q9DB50 1.000 Q9DB50 →
Q3ZBS3 1.000 Q3ZBS3 →
P56377 1.000 P56377 →
O23685 1.000 O23685 →
O82201 0.998 O82201 →
Q9P7N2 0.998 Q9P7N2 →
Q8LEZ8 0.998 Q8LEZ8 →
P35181 0.996 P35181 →
B0G185 0.996 B0G185 →
Q96PC3 0.995 Q96PC3 →
Q4WS49 0.994 Q4WS49 →
Q54H39 0.993 Q54H39 →
Q9Y7L6 0.993 Q9Y7L6 →
Q7TN05 0.993 Q7TN05 →
Q00381 0.992 Q00381 →
Q5BFF8 0.992 Q5BFF8 →
Q3ZBB6 0.990 Q3ZBB6 →
Q59QC5 0.990 Q59QC5 →
Q54WW3 0.990 Q54WW3 →
Q54NZ4 0.990 Q54NZ4 →
Q9WVL1 0.990 Q9WVL1 →
Q7SAQ1 0.989 Q7SAQ1 →
Q09905 0.988 Q09905 →
Q9Y587 0.988 Q9Y587 →
P35604 0.987 P35604 →
Q84WL9 0.986 Q84WL9 →
Q4ICG5 0.986 Q4ICG5 →
P61923 0.985 P61923 →