AP2S1

AP-2 complex subunit sigma · P53680 · AP2S1 on Sugi Atlas →

0 patent compounds predicted against AP2S1, 0 high-confidence (nearest known ligand ≥ 0.5)

Top predicted compounds (top 20 by supporting neighbours, then confidence)

CompoundConfidenceSupporting neighbours

Clinical trials — most relevant to AP2S1 by text similarity (a relevance ranking, not an exhaustive list)

TrialPhaseStatus
Mechanisms of Lipodystrophy in HIV-Infected Pateints PHASE4COMPLETED
Melpida: Recombinant Adeno-associated Virus (serotype 9) Encoding a Codon Optimized Human AP4M1 Transgene (hAP4M1opt) PHASE1/PHASE2RECRUITING
A Study of Bezafibrate in Mitochondrial Myopathy PHASE2COMPLETED
Effect of Deferoxamine on Wound Healing Rate in Patients With Diabetes Foot Ulcers PHASE2NOT_YET_RECRUITING
Value of Using Pioglitazone in Chronic Myeloid Leukemia Treatment PHASE2COMPLETED
Phase II Study of Vandetanib in Individuals With Kidney Cancer PHASE2COMPLETED
A Study Evaluating Megestrol Acetate Modulation in Hormone Receptor Positive Advanced Breast Cancer PHASE2UNKNOWN
Temsirolimus and Sorafenib in Advanced Hepatocellular Carcinoma PHASE1COMPLETED
A Study of APX3330 in Patients With Advanced Solid Tumors PHASE1COMPLETED
Autophagy in Systemic Lupus Erythematosus nanUNKNOWN
Diagnosis of RSTS: Identification of the Acetylation Profiles as Epigenetic Markers for Assessing Causality of CREBBP and EP300 Variants. nanUNKNOWN
Neurobiological and Neurocognitive Disturbances in First-episode Schizophrenia nanCOMPLETED
Defective Atypical Protein Kinase C (PKC) Activation in Diabetes and Metabolic Syndrome nanCOMPLETED
Genetic Analysis of Heart Channelopathies in Brazilian Patients and Their Relatives nanUNKNOWN
Genetic Screening and Assisted Oocyte Activation in Couples with Diminished/aberrant Embryonic Development. nanCOMPLETED
Regulation of Lymphocyte Anti-tumor Response in Metastatic Patients Treated With the mTOR Inhibitor Everolimus nanCOMPLETED
Role of SF3B1 Mutation in Assessment of Acute and Chronic Lymphatic Leukemia nanNOT_YET_RECRUITING
Remote Ischemic Postconditioning Increases HIF-1α Plasma Levels and Improves Cardiac Markers After Cardiac Surgery nanCOMPLETED
High Altitude Medical Research Expedition Himlung 2013 - a Study of Human Adaption to Hypoxia nanCOMPLETED
Genetic Analysis of Gray Platelet Syndrome nanCOMPLETED
Modeling DNA Diversity in Reverse Cholesterol Transport nanCOMPLETED
Recombinant Interferon Alfa-2b in Treating Patients With Melanoma nanCOMPLETED
MERC Proteins in Saliva and GCF in Periodontal Disease (ELISA Study) nanCOMPLETED
JAK-STAT Signalling Pathway in Familial Myeloproliferative Disorders nanCOMPLETED
Immune Cell Response to Stimuli nanRECRUITING
Genetic Study of Schizophrenia nanCOMPLETED
Protein Synthesis in the Brain of Patients With Fragile X Syndrome nanCOMPLETED
Identifying Genes and Mutations Underlying Retinitis Pigmentosa and Allied Diseases nanUNKNOWN
Bipolar Disorder Integrative Staging: Incorporating Biomarkers Into Progression Across Stages nanACTIVE_NOT_RECRUITING
Evaluation of the Predictive Effect of Inflammatory Markers in MI Patients nanUNKNOWN

Related proteins — ESM-2 sequence neighbours (a AP2S1 binder may also engage these)

ProteinNameSimilarity
Q5R940 1.000 Q5R940 →
P62744 1.000 P62744 →
P62743 1.000 P62743 →
Q17QC5 1.000 Q17QC5 →
Q54H39 0.994 Q54H39 →
Q7SAQ1 0.991 Q7SAQ1 →
Q84WL9 0.988 Q84WL9 →
O50016 0.988 O50016 →
Q4ICG5 0.985 Q4ICG5 →
Q4WS49 0.984 Q4WS49 →
Q9Y7L6 0.979 Q9Y7L6 →
Q5BFF8 0.979 Q5BFF8 →
B0G185 0.977 B0G185 →
O82201 0.976 O82201 →
Q553S2 0.974 Q553S2 →
O23685 0.973 O23685 →
P61967 0.972 P61967 →
Q96PC3 0.972 Q96PC3 →
AP1S1 AP-1 complex subunit sigma-1A 0.971 landscape →
Q1JQ98 0.970 Q1JQ98 →
Q8VZ37 0.969 Q8VZ37 →
Q9DB50 0.969 Q9DB50 →
Q3ZBS3 0.969 Q3ZBS3 →
P56377 0.969 P56377 →
Q7TN05 0.968 Q7TN05 →
Q9P7N2 0.968 Q9P7N2 →
Q8LEZ8 0.968 Q8LEZ8 →
P35181 0.967 P35181 →
Q59QC5 0.967 Q59QC5 →
Q3ZBB6 0.967 Q3ZBB6 →