AQP3

Aquaporin-3 · Q92482 · AQP3 on Sugi Atlas →

16 patent compounds predicted against AQP3, 5 high-confidence (nearest known ligand ≥ 0.5)

Top predicted compounds (top 20 by supporting neighbours, then confidence)

CompoundConfidenceSupporting neighbours
SCHEMBL13504042 SCHEMBL13504042 0.55 1/20
Fumaric Acid Fumaric Acid (SCHEMBL31237382) 0.52 1/20
SCHEMBL13681480 SCHEMBL13681480 0.50 1/20
SCHEMBL11472882 SCHEMBL11472882 0.44 1/20
SCHEMBL11262967 SCHEMBL11262967 0.40 1/20

Clinical trials — most relevant to AQP3 by text similarity (a relevance ranking, not an exhaustive list)

TrialPhaseStatus
The Effect of Indomethacin in Monosymptomatic Enuresis Nocturnal PHASE4COMPLETED
A Study to Assess the Effectiveness and Safety of Ozanimod in Chinese Adults With Relapsing Multiple Sclerosis PHASE4ACTIVE_NOT_RECRUITING
Urinary Aquaporine 2 in Patients With Syndrome of Inappropriate ADH-secretion Caused by Treatment With Antiepileptic Medicine PHASE4WITHDRAWN
Reduction of Edema With a Specialized Cocktail for Ultra-early Management in Intracerebral Hemorrhage PHASE3NOT_YET_RECRUITING
Study of Stroke Related Edema Treatments PHASE2WITHDRAWN
The Role of Vasopressin Antagonism on Renal Sodium Handling PHASE1COMPLETED
Conivaptan for the Reduction of Cerebral Edema in Intracerebral Hemorrhage- A Safety and Tolerability Study PHASE1COMPLETED
Effect of Statin Treatment on Urinary AQP2 (uAQP2/01) nanCOMPLETED
The Effect of High and Low Sodium Intake on Urinary Aquaporin-2 in Healthy Humans. nanCOMPLETED
Asymptomatic Bacteriuria, Hyponatremia and Geri-atric Syndrome nanCOMPLETED
Biomarkers in the Etiology of Idiopathic Intracranial Hypertension nanUNKNOWN
Nocturnal Blood Pressure and Hypertension - Central and Peripheral 24-h Blood Pressure. nanUNKNOWN
Neuroimaging Risk of Postoperative Delirium nanUNKNOWN
Prospective Evaluation of the 2022 Optic Neuritis Criteria When Optic Neuritis Is Suspected nanRECRUITING
Preoperative Prediction of of Thymic Epithelial Tumors by Diffusion-Weighted MR Imaging nanUNKNOWN
Clinical Patterns of Neuromyelitis Optica Spectrum Disorders in Assiut University Hospital nanCOMPLETED
Effect of Hypertonic Sodium Chloride on Urinary Biomarkers in Healthy Subjects and Patients With Chronic Kidney Disease nanCOMPLETED
The Effect of High and Low Sodium Intake on Urinary Aquaporin-2 in Essential Hypertension nanCOMPLETED
The Expression of Aquaporin 3, 8 and 9 in Placenta in Normal and Preeclamptic Pregnancies: Perinatal and Neonatal Outcomes. nanUNKNOWN
Efficacy of a Water Intervention in Institutionalized Aged Population. nanCOMPLETED
Imaging - Clinical Evaluation of Altered Nervous System Drainage nanUNKNOWN
Acute Optic Neuritis Network: an International Study That Invesitages Subjects With a First-ever Episode of Acute Inflammation of the Optic Nerve nanUNKNOWN
The Correlation Between AQP-4 Ab and the Visual Function of Patients With Demyelinating ON at Onset nanUNKNOWN
non_invasive_aICP_Tumor nanCOMPLETED
Urinary Aquaporin 2 and Expression of the NPHS2 Gene in Adults Suffering From Nephrotic Syndrome nanCOMPLETED
The Effect of Thiazide, Amiloride and Hypertonic Saline on Urinary Biomarkers in Healthy Subjects nanCOMPLETED
In Vitro Study of the Biological and Immunological Activity of Imotopes® Candidates on Blood Cells of Patients With Stabilized NMO nanCOMPLETED
Microbiota in COVID-19 Patients for Future Therapeutic and Preventive Approaches nanUNKNOWN
Monoclonal Antibody-Based Therapies for AQP4-Positive NMOSD nanRECRUITING
Study of Genotype and Phenotype Expression in Congenital Nephrogenic Diabetes Insipidus nanCOMPLETED

Related proteins — ESM-2 sequence neighbours (a AQP3 binder may also engage these)

ProteinNameSimilarity
Q08DE6 1.000 Q08DE6 →
P47862 1.000 P47862 →
Q8R2N1 1.000 Q8R2N1 →
A9Y006 1.000 A9Y006 →
Q96PS8 0.992 Q96PS8 →
O43315 0.991 O43315 →
P56627 0.989 P56627 →
Q866S3 0.986 Q866S3 →
P56402 0.985 P56402 →
A2IBY8 0.985 A2IBY8 →
P34080 0.984 P34080 →
Q6J8I9 0.984 Q6J8I9 →
P30301 0.983 P30301 →
P47864 0.983 P47864 →
O62735 0.982 O62735 →
P09011 0.982 P09011 →
Q6RZ07 0.982 Q6RZ07 →
B0D4E4 0.981 B0D4E4 →
P41181 0.981 P41181 →
A8W649 0.981 A8W649 →
P06624 0.980 P06624 →
Q9JJJ3 0.980 Q9JJJ3 →
A4L9J0 0.980 A4L9J0 →
Q9WTY4 0.980 Q9WTY4 →
P79099 0.979 P79099 →
P29975 0.979 P29975 →
P55064 0.979 P55064 →
P47865 0.978 P47865 →
AQP1 Aquaporin-1 0.978 landscape →
Q23808 0.977 Q23808 →