ARF1

ADP-ribosylation factor 1 · P84077 · ARF1 on Sugi Atlas →

9 patent compounds predicted against ARF1, 8 high-confidence (nearest known ligand ≥ 0.5)

Top predicted compounds (top 20 by supporting neighbours, then confidence)

CompoundConfidenceSupporting neighbours
SCHEMBL1056416 SCHEMBL1056416 1.00 1/20
SCHEMBL1056417 SCHEMBL1056417 1.00 1/20
SCHEMBL29358731 SCHEMBL29358731 1.00 1/20
SCHEMBL30753542 SCHEMBL30753542 1.00 1/20
Water Water (SCHEMBL29794967) 0.98 1/20
SCHEMBL28800958 SCHEMBL28800958 0.55 1/20
SCHEMBL28800959 SCHEMBL28800959 0.55 1/20
SCHEMBL24421960 SCHEMBL24421960 0.44 1/20

Clinical trials — most relevant to ARF1 by text similarity (a relevance ranking, not an exhaustive list)

TrialPhaseStatus
Treatment With HMG-COA Reductase Inhibitor of Growth and Bone Abnormalities in Children With Noonan Syndrome PHASE3COMPLETED
Safety and Efficacy of AAV9/AP4B1 (BFB-101) For Patients With AP4B1-related Hereditary Spastic Paraplegia Type 47 (SPG47) PHASE1/PHASE2NOT_YET_RECRUITING
Melpida: Recombinant Adeno-associated Virus (serotype 9) Encoding a Codon Optimized Human AP4M1 Transgene (hAP4M1opt) PHASE1/PHASE2RECRUITING
Reverse Transcriptase Inhibitors in AGS PHASE2COMPLETED
Sirolimus Treatment in Patients With Autosomal Dominant Polycystic Kidney Disease: Renal Efficacy and Safety PHASE2COMPLETED
Safety Evaluation of Gene Therapy in Leber Hereditary Optic Neuropathy (LHON) Patients PHASE1/PHASE2COMPLETED
Antioxidant Therapy With N-acetylcysteine for Learning and Motor Behavior in Children With Neurofibromatosis Type 1 PHASE2COMPLETED
Investigator-initiated Clinical Trial of MIKE-1 PHASE1/PHASE2UNKNOWN
Temsirolimus and Sorafenib in Advanced Hepatocellular Carcinoma PHASE1COMPLETED
Nilotinib in Huntington's Disease PHASE1UNKNOWN
Interleukin-2 Treatment for Wiskott-Aldrich Syndrome PHASE1COMPLETED
Dynamics of Muscle Mitochondria in Type 2 Diabetes (DYNAMMO T2D) EARLY_PHASE1COMPLETED
Prospective Validation of a DNA Damage Repair-Hippo Pathway Signature in Patients With Advanced Gastric Cancer nanUNKNOWN
Autophagy in Systemic Lupus Erythematosus nanUNKNOWN
Study of Proteins in Head and Neck Cancer Cells nanCOMPLETED
Genetics of Endocrine Tumours - Familial Isolated Pituitary Adenoma - FIPA nanRECRUITING
Genetic Characterization of Parkinson's Disease nanCOMPLETED
Study of the Pathophysiological Mechanisms Involved in Bleeding Events nanCOMPLETED
Genetic Analysis of Gray Platelet Syndrome nanCOMPLETED
Association of Autophagy-related Genes ,LncRNA and SNPs With Colorectal Cancer in Egyptian Population nanCOMPLETED
Towards an Easy-to-use Adrenal Cancer/Tumor Identity Card nanCOMPLETED
GNAO1 Natural History Study nanUNKNOWN
Mapping Disease Pathways for Biliary Atresia nanRECRUITING
Classification, Functional Stratification and Biomarkers in Ciliopathy (CILLICORIRCM) nanCOMPLETED
Sexually Dimorphic Effects of GHRH in Adult Growth Hormone Testing nanCOMPLETED
Value of MicroRNA30a in Philadelphia Positive Leukemic Patients nanUNKNOWN
Study of the Genetic and Epigenetic Causes of Recurrent Hydatidiform Moles nanACTIVE_NOT_RECRUITING
Identification of New Biomarkers of Insulin Resistance nanACTIVE_NOT_RECRUITING
GARM II: A Study on the Genetics of Age-related Maculopathy nanACTIVE_NOT_RECRUITING
Characterization of New Candidate Genes in Cases of Human Inherited Thrombocytopenia (CATCH) nanCOMPLETED

Related proteins — ESM-2 sequence neighbours (a ARF1 binder may also engage these)

ProteinNameSimilarity
Q5E9I6 1.000 Q5E9I6 →
P61204 1.000 P61204 →
Q5R5P7 1.000 Q5R5P7 →
P61205 1.000 P61205 →
P61207 1.000 P61207 →
P84080 1.000 P84080 →
P84082 1.000 P84082 →
P61206 1.000 P61206 →
Q75A26 1.000 Q75A26 →
P51822 1.000 P51822 →
P22274 1.000 P22274 →
Q4R5P2 1.000 Q4R5P2 →
Q7RVM2 0.999 Q7RVM2 →
P84081 0.999 P84081 →
P84078 0.999 P84078 →
P84079 0.999 P84079 →
Q8BSL7 0.999 Q8BSL7 →
O48920 0.999 O48920 →
P51643 0.998 P51643 →
O48649 0.998 O48649 →
Q06396 0.998 Q06396 →
P61210 0.997 P61210 →
P36579 0.997 P36579 →
P61209 0.997 P61209 →
Q9LQC8 0.997 Q9LQC8 →
Q10943 0.997 Q10943 →
P49076 0.997 P49076 →
P51821 0.997 P51821 →
P36397 0.997 P36397 →
P51823 0.997 P51823 →