SCHEMBL29358731

SCHEMBL29358731

OC[C@H](Cc1ccccc1)Nc1nc(Oc2ccc3c(c2)CCC3)nc2c1ncn2Cc1ccc(-c2ccccc2)cc1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ARF1 P84077 1/20 1.00
ARFGAP1 Q8N6T3 1/20 1.00
CCNE2 O96020 2/20 0.41
CCNE1 P24864 2/20 0.41
CDK2 P24941 2/20 0.41
ADORA1 P30542 1/20 0.38
CDK1 P06493 3/20 0.38
CDK5 Q00535 2/20 0.38
ADORA2A P29274 1/20 0.38
YTHDC1 Q96MU7 1/20 0.37
MMEL1 Q495T6 1/20 0.37
CCNK O75909 1/20 0.36
CCNA2 P20248 1/20 0.36
CCNA1 P78396 1/20 0.36
CDK12 Q9NYV4 1/20 0.36
CTSL P07711 2/20 0.36
PDE4A P27815 1/20 0.35
PDE4B Q07343 1/20 0.35
PDE4C Q08493 1/20 0.35
PDE4D Q08499 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30753542 1.00 ARF1 (1.00) ARF1ARFGAP1CCNE2CCNE1CDK2
SCHEMBL1056416 1.00 ARF1 (1.00) ARF1ARFGAP1CCNE2CCNE1CDK2
SCHEMBL1056417 1.00 ARF1 (1.00) ARF1ARFGAP1CCNE2CCNE1CDK2
Water SCHEMBL29794967 0.99 ARF1 (0.98) ARF1ARFGAP1CCNE2CCNE1CDK2
SCHEMBL28800958 0.71 ARF1 (0.55) ARF1ARFGAP1ADORA2A
SCHEMBL28800959 0.71 ARF1 (0.55) ARF1ARFGAP1ADORA2A
SCHEMBL24421960 0.61 ADORA1 (0.53) ARF1ARFGAP1CDK2ADORA1CDK1
SCHEMBL24421964 0.60 EGFR (0.44) ARF1ARFGAP1CDK2ADORA1CDK1
SCHEMBL28232483 0.59 CDK2 (0.84) CCNE2CCNE1CDK2CDK1CDK5
SCHEMBL28950097 0.59 YTHDC1 (0.52) CDK1ADORA2AYTHDC1CTSLPDE4A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 277 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12577530-B2 Generation of a population of hindbrain cells and hindbrain-like organoids from pluripotent stem cells THE J. DAVID GLADSTONE INSTITUTES, A TESTAMENTARY TRUST ESTABLISHED UNDER THE WILL OF J. DAVID GLADSTONE (US) 2026-03-17 US claimed
US-20260002134-A1 CHOROID PLEXUS ORGANOIDS AND METHODS FOR PRODUCTION THEREOF UNITED KINGDOM RESEARCH AND INNOVATION (GB) 2026-01-01 US claimed
US-20250376659-A1 DERIVATION OF SOMATOTROPHS FROM STEM CELLS AND USES THEREOF MEMORIAL SLOAN-KETTERING CANCER CENTER (US) 2025-12-11 US claimed
US-12428622-B2 Organoid compositions for the production of hematopoietic stem cells and derivatives thereof CHILDREN'S HOSPITAL MEDICAL CENTER (US) 2025-09-30 US claimed
CN-112444691-B Comprehensive test board for power supply screen input 通号(西安)轨道交通工业集团有限公司 2025-06-10 CN claimed
CN-120036159-A Warmhouse booth temperature regulation and control system based on low-grade heat source 重庆大学 2025-05-27 CN claimed
CN-113631701-B Choroid plexus organ and method for producing same 英国研究与创新组织 2025-03-14 CN claimed
EP-4516305-A1 METHOD AND COMPOSITION FOR PREVENTING OR TREATING MYOPIA Tsubota Laboratory, Inc. (JP) 2025-03-05 EP claimed
CN-222234706-U High-voltage frequency conversion system for starting permanent magnet synchronous motor 中国电力工程顾问集团东北电力设计院有限公司 2024-12-24 CN claimed
US-20240409892-A1 METHOD OF DIRECTED DIFFERENTIATION PRODUCING CORNEAL ENDOTHELIAL CELLS, COMPOSITIONS THEREOF, AND USES THEREOF ASTELLAS INSTITUTE FOR REGENERATIVE MEDICINE (US) 2024-12-12 US claimed
WO-2022246112-A1 CHIMERIC ANTIGEN RECEPTOR-MODIFIED GRANULOCYTE-MACROPHAGE PROGENITORS FOR CANCER IMMUNOTHERAPY UNIVERSITY OF SOUTHERN CALIFORNIA (US) 2022-11-24 WO claimed
WO-2022226337-A1 METHOD FOR PRODUCING HEMATOPOIETIC CELLS FROM STEM CELLS USING VASCULAR ORGANOIDS Artec Biotech, Inc. (US) 2022-10-27 WO claimed
CN-217160060-U Color temperature switching de-pulsing circuit 宁波凯耀电器制造有限公司 2022-08-09 CN claimed
CN-114533039-A Human body joint position and angle calculating method based on redundant sensors 重庆邮电大学 2022-05-27 CN claimed
CN-216599462-U Electrical control system 苏州汇川控制技术有限公司 2022-05-24 CN claimed
CN-114499345-A Multipurpose switching method for KHV high-voltage variable-frequency speed regulation system of intelligent power supply 山东凯迪欧电气有限公司 2022-05-13 CN claimed
US-20220106571-A1 CHOROID PLEXUS ORGANOIDS AND METHODS FOR PRODUCTION THEREOF UNITED KINGDOM RESEARCH AND INNOVATION (GB) 2022-04-07 US claimed
WO-2022042527-A1 SMALL-MOLECULE DRUG FOR TREATING DISEASES RELATED TO INNER EAR AND INTESTINAL EPITHELIAL TISSUE INJURIES 北京大学 2022-03-03 WO claimed
CN-114085803-A Establishment of organoid culture systems with regenerative properties 北京大学 2022-02-25 CN claimed
CN-215681909-U Control device for double-bus double-frequency-converter double-motor dragging 新风光电子科技股份有限公司 2022-01-28 CN claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12577530-B2 Generation of a population of hindbrain cells and hindbrain-like organoids from pluripotent stem cells SHH, SMO, WNT3A ARF1 3890/4885ARFGAP1 4617/4885CCNE2 988/4885
US-20260002134-A1 CHOROID PLEXUS ORGANOIDS AND METHODS FOR PRODUCTION THEREOF BMP4, WNT3A, BMP1 ARF1 4478/4885ARFGAP1 4193/4885CCNE2 802/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.