ARF6

ADP-ribosylation factor 6 · P62330 · ARF6 on Sugi Atlas →

1,127 patent compounds predicted against ARF6, 289 high-confidence (nearest known ligand ≥ 0.5)

Top predicted compounds (top 20 by supporting neighbours, then confidence)

CompoundConfidenceSupporting neighbours
SCHEMBL20767271 SCHEMBL20767271 1.00 20/20
SCHEMBL20796202 SCHEMBL20796202 1.00 20/20
SCHEMBL20796203 SCHEMBL20796203 1.00 20/20
SCHEMBL20796212 SCHEMBL20796212 1.00 20/20
SCHEMBL20796215 SCHEMBL20796215 1.00 20/20
SCHEMBL20796235 SCHEMBL20796235 1.00 20/20
SCHEMBL20796236 SCHEMBL20796236 1.00 20/20
SCHEMBL20796458 SCHEMBL20796458 1.00 20/20
SCHEMBL20796483 SCHEMBL20796483 1.00 20/20
SCHEMBL20796484 SCHEMBL20796484 1.00 20/20
SCHEMBL20796486 SCHEMBL20796486 1.00 20/20
SCHEMBL20796518 SCHEMBL20796518 1.00 20/20
SCHEMBL20796531 SCHEMBL20796531 1.00 20/20
SCHEMBL22902184 SCHEMBL22902184 1.00 20/20
SCHEMBL22902192 SCHEMBL22902192 1.00 20/20
SCHEMBL22902193 SCHEMBL22902193 1.00 20/20
SCHEMBL22902196 SCHEMBL22902196 1.00 20/20
SCHEMBL22902199 SCHEMBL22902199 1.00 20/20
SCHEMBL22902389 SCHEMBL22902389 1.00 20/20
Trifluoroacetic Acid Trifluoroacetic Acid (SCHEMBL29865926) 1.00 20/20

Clinical trials — most relevant to ARF6 by text similarity (a relevance ranking, not an exhaustive list)

TrialPhaseStatus
A Phase 3 Study Of OCU400 Gene Therapy for the Treatment Of Retinitis Pigmentosa PHASE3ACTIVE_NOT_RECRUITING
Safety and Efficacy of AAV9/AP4B1 (BFB-101) For Patients With AP4B1-related Hereditary Spastic Paraplegia Type 47 (SPG47) PHASE1/PHASE2NOT_YET_RECRUITING
Reverse Transcriptase Inhibitors in AGS PHASE2COMPLETED
Melpida: Recombinant Adeno-associated Virus (serotype 9) Encoding a Codon Optimized Human AP4M1 Transgene (hAP4M1opt) PHASE1/PHASE2RECRUITING
Temsirolimus and Sorafenib in Advanced Hepatocellular Carcinoma PHASE1COMPLETED
Interleukin-2 Treatment for Wiskott-Aldrich Syndrome PHASE1COMPLETED
Autophagy in Systemic Lupus Erythematosus nanUNKNOWN
Whole Genome Scan of Extended Families With Familial Vocal Cord Paralysis nanCOMPLETED
Evaluation of the Predictive Effect of Inflammatory Markers in MI Patients nanUNKNOWN
Characterization of New Candidate Genes in Cases of Human Inherited Thrombocytopenia (CATCH) nanCOMPLETED
Autophagy Bladder Cancer nanUNKNOWN
Genetics of Endocrine Tumours - Familial Isolated Pituitary Adenoma - FIPA nanRECRUITING
A Study of the Interaction Between Tumor Susceptibility Gene Glycine N-methyltransferase (GNMT) and Lung Cancer nanUNKNOWN
Identification of New Biomarkers of Insulin Resistance nanACTIVE_NOT_RECRUITING
Genetic Analysis of Gray Platelet Syndrome nanCOMPLETED
The Cognitive Resilience Study nanCOMPLETED
ADRB3, ROCK2 and GEF Levels in Overactive Bladder Patients nanCOMPLETED
Assessing the Polygenic Burden of Rare Disruptive Mutations in Parkinson's Disease nanUNKNOWN
Classification, Functional Stratification and Biomarkers in Ciliopathy (CILLICORIRCM) nanCOMPLETED
Biomarker Research in Inherited Movement Disorders nanRECRUITING
Genetic Analysis of Familial Melanoma nanCOMPLETED
Molecular Genetics Study of Nasopharyngeal Carcinoma: Characterization of NCP Susceptibility Gene(s) nanCOMPLETED
Identification of Genetic Factors Implicated in Orofacial Cleft Using Whole Exome Sequencing nanRECRUITING
Genetic Characterization of Parkinson's Disease nanCOMPLETED
Chromosome 5Q Gene Variants and Asthma-Related Traits nanCOMPLETED
Mapping Disease Pathways for Biliary Atresia nanRECRUITING
Study of the Pathophysiological Mechanisms Involved in Bleeding Events nanCOMPLETED
Identifying Genes and Mutations Underlying Retinitis Pigmentosa and Allied Diseases nanUNKNOWN
Identification of a New Gene Involved in Hereditary Lipodystrophy nanCOMPLETED
GARM II: A Study on the Genetics of Age-related Maculopathy nanACTIVE_NOT_RECRUITING

Related proteins — ESM-2 sequence neighbours (a ARF6 binder may also engage these)

ProteinNameSimilarity
P62331 1.000 P62331 →
Q007T5 1.000 Q007T5 →
P62332 1.000 P62332 →
P40946 1.000 P40946 →
P26990 1.000 P26990 →
P51645 1.000 P51645 →
Q5E9I6 1.000 Q5E9I6 →
P61204 1.000 P61204 →
Q75A26 1.000 Q75A26 →
P22274 1.000 P22274 →
P61206 1.000 P61206 →
Q25761 1.000 Q25761 →
P51822 1.000 P51822 →
O48920 1.000 O48920 →
P61207 1.000 P61207 →
Q5RCF1 1.000 Q5RCF1 →
O48649 1.000 O48649 →
Q7KQL3 1.000 Q7KQL3 →
P61750 1.000 P61750 →
P51821 1.000 P51821 →
Q06396 1.000 Q06396 →
P49076 1.000 P49076 →
ARF4 ADP-ribosylation factor 4 1.000 landscape →
Q7RVM2 1.000 Q7RVM2 →
Q5R5P7 0.999 Q5R5P7 →
P61205 0.999 P61205 →
Q8BSL7 0.999 Q8BSL7 →
P84081 0.999 P84081 →
P36579 0.999 P36579 →
P34727 0.999 P34727 →