ARPC1B — patent landscape

Top predicted compounds (top 20 by supporting neighbours, then confidence)

Compound	Confidence	Supporting neighbours
SCHEMBL4699731	1.00	2/20
SCHEMBL4697866	0.89	2/20
SCHEMBL4697696	0.86	2/20
SCHEMBL4699947	0.83	2/20
SCHEMBL4699140	0.80	2/20
SCHEMBL4922941	0.80	2/20
SCHEMBL4916509	0.78	2/20
SCHEMBL4700123	0.77	2/20
SCHEMBL4698636	0.76	2/20
SCHEMBL4917606	0.76	2/20
SCHEMBL4908396	0.74	2/20
SCHEMBL4699183	0.74	2/20
SCHEMBL4914310	0.73	2/20
SCHEMBL4915098	0.73	2/20
SCHEMBL4696222	0.72	2/20
SCHEMBL4701699	0.70	2/20
SCHEMBL4698169	0.70	2/20
SCHEMBL4696537	0.68	2/20
SCHEMBL4920392	0.66	2/20
SCHEMBL14070246	0.63	2/20

Clinical trials — most relevant to ARPC1B by text similarity (a relevance ranking, not an exhaustive list)

Trial	Phase	Status
Treatment of Ectopic Calcification in Fahr's Disease or Syndrome	PHASE2	RECRUITING
Muscle Tissue Bank for Muscular Dystrophy	nan	COMPLETED
Signs and Symptoms of Genetic Abnormalities Linked to Inherited Heart Disease	nan	COMPLETED
Genetic Characterization of Parkinson's Disease	nan	COMPLETED
Mapping Novel Disease Genes for Dilated Cardiomyopathy	nan	COMPLETED
Signs and Symptoms Associated With Molecular Defects in Genetically Inherited Heart Disease	nan	COMPLETED
Classification, Functional Stratification and Biomarkers in Ciliopathy (CILLICORIRCM)	nan	COMPLETED
Pediatric Evaluation and Registry for Liver Cholestasis in Canada	nan	RECRUITING
Diagnosis of Primary Ciliary Dyskinesia	nan	COMPLETED
Identifying Genes and Mutations Underlying Retinitis Pigmentosa and Allied Diseases	nan	UNKNOWN
Clinical Importance of Carrier Status of Recessive Gene Mutations in Myopathy (CICS)	nan	UNKNOWN
Autophagy in Systemic Lupus Erythematosus	nan	UNKNOWN
PCD New Gene Discovery	nan	COMPLETED
Neurogenetics Patient Registry	nan	RECRUITING
New Strategies of Genetic Study of Patients With Oculocutaneous Albinism	nan	COMPLETED
Characterization of New Candidate Genes in Cases of Human Inherited Thrombocytopenia (CATCH)	nan	COMPLETED
Pediatric Cardiomyopathy Mutation Analysis	nan	RECRUITING
Genotype-Phenotype Associations in Pediatric Cardiomyopathy (PCM GENES)	nan	COMPLETED
Study of the Pathophysiological Mechanisms Involved in Bleeding Events	nan	COMPLETED
Family Blood Pressure Program - GenNet Network	nan	COMPLETED
Mayo AVC Registry and Biobank	nan	RECRUITING
Characterization of WAGR Syndrome and Other Chromosome 11 Gene Deletions	nan	COMPLETED
Genetics of Pediatric-Onset Motor Neuron and Neuromuscular Diseases	nan	COMPLETED
Family Blood Pressure Program - SAPPHIRe Network	nan	COMPLETED
Phenotype/Genotype Correlations in Neuromuscular Disorders	nan	COMPLETED
Biomarkers in SCOTland CardiomyopatHy Registry (Bio-SCOTCH)	nan	RECRUITING
Clinical and Laboratory Analysis of Familial Cancer	nan	COMPLETED
Pathogenesis of Primary Ciliary Dyskinesia (PCD) Lung Disease	nan	RECRUITING
Genetic Analysis of Familial Hypertrophic Cardiomyopathy	nan	COMPLETED
Regulation of Lymphocyte Anti-tumor Response in Metastatic Patients Treated With the mTOR Inhibitor Everolimus	nan	COMPLETED

Related proteins — ESM-2 sequence neighbours (a ARPC1B binder may also engage these)

Protein	Name	Similarity
Q9WV32	—	1.000	Q9WV32 →
Q58CQ2	—	1.000	Q58CQ2 →
O88656	—	1.000	O88656 →
Q6GNU1	—	0.997	Q6GNU1 →
Q7ZXD5	—	0.995	Q7ZXD5 →
O80856	—	0.988	O80856 →
Q9SJW6	—	0.983	Q9SJW6 →
O96622	—	0.981	O96622 →
SEC13	Protein SEC13 homolog	0.976	landscape →
Q9D1M0	—	0.976	Q9D1M0 →
Q5XFW8	—	0.975	Q5XFW8 →
Q3ZCC9	—	0.975	Q3ZCC9 →
B6QC56	—	0.975	B6QC56 →
Q8BU03	—	0.973	Q8BU03 →
O95834	—	0.972	O95834 →
Q8K057	—	0.972	Q8K057 →
Q6CSZ5	—	0.972	Q6CSZ5 →
Q2KJH4	—	0.972	Q2KJH4 →
Q9S7I8	—	0.972	Q9S7I8 →
Q6BZX5	—	0.972	Q6BZX5 →
O00423	—	0.971	O00423 →
Q7K4B3	—	0.971	Q7K4B3 →
Q7K2X8	—	0.971	Q7K2X8 →
Q6P6T4	—	0.971	Q6P6T4 →
Q66HB3	—	0.970	Q66HB3 →
A5DHD9	—	0.970	A5DHD9 →
O88342	—	0.970	O88342 →
Q9P2H3	—	0.970	Q9P2H3 →
O64740	—	0.970	O64740 →
Q9SZA4	—	0.970	Q9SZA4 →