ARPC3

Actin-related protein 2/3 complex subunit 3 · O15145 · ARPC3 on Sugi Atlas →

276 patent compounds predicted against ARPC3, 257 high-confidence (nearest known ligand ≥ 0.5)

Top predicted compounds (top 20 by supporting neighbours, then confidence)

CompoundConfidenceSupporting neighbours
SCHEMBL4699731 SCHEMBL4699731 1.00 2/20
SCHEMBL16111548 SCHEMBL16111548 1.00 2/20
SCHEMBL29358745 SCHEMBL29358745 1.00 2/20
SCHEMBL29380618 SCHEMBL29380618 1.00 2/20
SCHEMBL29931136 SCHEMBL29931136 1.00 2/20
SCHEMBL4697866 SCHEMBL4697866 0.89 2/20
SCHEMBL24532075 SCHEMBL24532075 0.89 2/20
SCHEMBL4697696 SCHEMBL4697696 0.86 2/20
SCHEMBL23092285 SCHEMBL23092285 0.86 2/20
SCHEMBL29688472 SCHEMBL29688472 0.86 2/20
SCHEMBL22024695 SCHEMBL22024695 0.86 2/20
SCHEMBL16136600 SCHEMBL16136600 0.84 2/20
SCHEMBL24532058 SCHEMBL24532058 0.83 2/20
SCHEMBL4699947 SCHEMBL4699947 0.83 2/20
SCHEMBL22025026 SCHEMBL22025026 0.82 2/20
SCHEMBL22119546 SCHEMBL22119546 0.82 2/20
SCHEMBL24532062 SCHEMBL24532062 0.82 2/20
SCHEMBL18804561 SCHEMBL18804561 0.81 2/20
SCHEMBL22024561 SCHEMBL22024561 0.81 2/20
SCHEMBL22025030 SCHEMBL22025030 0.81 2/20

Clinical trials — most relevant to ARPC3 by text similarity (a relevance ranking, not an exhaustive list)

TrialPhaseStatus
Treatment of Ectopic Calcification in Fahr's Disease or Syndrome PHASE2RECRUITING
Muscle Tissue Bank for Muscular Dystrophy nanCOMPLETED
Clinical and Biochemical Features for the Identification of Dominant Calpainopathies nanUNKNOWN
Family Blood Pressure Program - GenNet Network nanCOMPLETED
Signs and Symptoms of Genetic Abnormalities Linked to Inherited Heart Disease nanCOMPLETED
Autophagy in Systemic Lupus Erythematosus nanUNKNOWN
Family Blood Pressure Program - HyperGEN nanCOMPLETED
Signs and Symptoms Associated With Molecular Defects in Genetically Inherited Heart Disease nanCOMPLETED
Study of the Pathophysiological Mechanisms Involved in Bleeding Events nanCOMPLETED
Mapping Novel Disease Genes for Dilated Cardiomyopathy nanCOMPLETED
Family Blood Pressure Program - GENOA nanCOMPLETED
Family Blood Pressure Program - SAPPHIRe Network nanCOMPLETED
Characterization of New Candidate Genes in Cases of Human Inherited Thrombocytopenia (CATCH) nanCOMPLETED
Evaluation of Limb-Girdle Muscular Dystrophy nanCOMPLETED
Genetic Characterization of Parkinson's Disease nanCOMPLETED
Chromosome 5Q Gene Variants and Asthma-Related Traits nanCOMPLETED
Identifying Genes and Mutations Underlying Retinitis Pigmentosa and Allied Diseases nanUNKNOWN
PCD New Gene Discovery nanCOMPLETED
Molecular Genetics of Retinal Degenerations nanCOMPLETED
A Patient-tailored Genetic/Biomarker/iPSC Combined Approach in ALS - PERMEALS nanRECRUITING
Diagnosis of Primary Ciliary Dyskinesia nanCOMPLETED
Mayo AVC Registry and Biobank nanRECRUITING
Integrins and Protocadherins in Glutamatergic Circuits: Identification of Common Signaling Pathways and Molecular Targets in Anxiety and Major Depressive Disorders (GAPsy) nanUNKNOWN
Classification, Functional Stratification and Biomarkers in Ciliopathy (CILLICORIRCM) nanCOMPLETED
New Strategies of Genetic Study of Patients With Oculocutaneous Albinism nanCOMPLETED
Genotype-Phenotype Associations in Pediatric Cardiomyopathy (PCM GENES) nanCOMPLETED
The Genetics of Cardiomyopathy and Heart Failure nanWITHDRAWN
PREcision Diagnostics in Rare genetIC Diseases and Tumors - Long Read Sequencing nanRECRUITING
Biomarkers in SCOTland CardiomyopatHy Registry (Bio-SCOTCH) nanRECRUITING
Pediatric Cardiomyopathy Mutation Analysis nanRECRUITING

Related proteins — ESM-2 sequence neighbours (a ARPC3 binder may also engage these)

ProteinNameSimilarity
Q3T035 1.000 Q3T035 →
Q9JM76 1.000 Q9JM76 →
A1DPK7 1.000 A1DPK7 →
Q7T0U5 1.000 Q7T0U5 →
Q5AAJ8 0.995 Q5AAJ8 →
P09877 0.995 P09877 →
Q784P6 0.993 Q784P6 →
Q83HQ6 0.992 Q83HQ6 →
Q1WTX9 0.992 Q1WTX9 →
P20402 0.991 P20402 →
Q32RZ2 0.991 Q32RZ2 →
P38475 0.991 P38475 →
Q83GH5 0.991 Q83GH5 →
B4SCX8 0.991 B4SCX8 →
P0CT27 0.990 P0CT27 →
B4S4Y9 0.990 B4S4Y9 →
P86225 0.990 P86225 →
Q86UN6 0.990 Q86UN6 →
P23554 0.990 P23554 →
B3SRX0 0.990 B3SRX0 →
P18611 0.989 P18611 →
Q96FN9 0.989 Q96FN9 →
Q9W850 0.989 Q9W850 →
Q65231 0.989 Q65231 →
O48397 0.989 O48397 →
Q03245 0.989 Q03245 →
C7ZPG2 0.989 C7ZPG2 →
Q2VED6 0.989 Q2VED6 →
P05673 0.989 P05673 →
Q1ECJ7 0.989 Q1ECJ7 →