ATP5PD — patent landscape

Top predicted compounds (top 20 by supporting neighbours, then confidence)

	Compound	Confidence	Supporting neighbours

Clinical trials — most relevant to ATP5PD by text similarity (a relevance ranking, not an exhaustive list)

Trial	Phase	Status
A Study of the Efficacy and Safety of MT1621 in Thymidine Kinase 2 (TK2) Deficiency (Treatment naïve)	PHASE3	WITHDRAWN
Clinical Evaluation of the Effect of Metformin in Sepsis	PHASE3	UNKNOWN
A Phase 2 Study to Assess the Effects of SUL-238 on High Energy Phosphates With ³¹P-MRS in Patients With Early, Untreated Parkinson's Disease	PHASE2	RECRUITING
Nicotinamide Riboside on Mitochondrial Function in Li-Fraumeni Syndrome	PHASE1/PHASE2	COMPLETED
Mitochondrial Dysfunction in the Pathophysiology and Treatment of Bipolar Disorder	PHASE2	WITHDRAWN
Tissue Sample Study for Mitochondrial Disorders	nan	ENROLLING_BY_INVITATION
Mitoquines in COPD	nan	UNKNOWN
GDF-15 as a Biomarker for Mitochondrial Disease	nan	COMPLETED
Mitochondrial Dysfunction in Phelan-McDermid Syndrome	nan	COMPLETED
Relationship Between Mitochondrial Dysfunction and Fatique in Cancer Patients Following External Beam Radiation Therapy	nan	COMPLETED
Assessing the Role of Mitochondrial Dysfunction in Primary Progressive Multiple Sclerosis	nan	UNKNOWN
Drug Repurposing for Mitochondrial Disorders Using iPSCs Derived Neural Cells	nan	RECRUITING
Calf Muscle Strength in Mitochondrial Diseases	nan	COMPLETED
Mitochondrial Methylation in Type 2 Diabetes	nan	COMPLETED
A Study Into the Underlying Biochemical Pathways Involved in Parkinson's Disease, Such as Mitochondrial (Cellular Powerhouse) Dysfunction	nan	COMPLETED
Choroid Plexus Dysfunction in Neurological Diseases	nan	RECRUITING
Lifestyle Intervention in Preparation for Pregnancy (LIPP)	nan	COMPLETED
Effect of Hypothyroidism on Brown Adipose Tissue	nan	COMPLETED
Mitochondrial Dysfunctions Driving Insulin Resistance	nan	COMPLETED
Transcranial Photobiomodulation Therapy for the Treatment of Autistic Traits in Children and Adolescents With ADHD	nan	COMPLETED
Evaluation of Transcranial Photobiomodulation in Autism Spectrum Disorder	nan	COMPLETED
Exercise-mediated Rescue of Mitochondrial Dysfunctions Driving Insulin Resistance	nan	COMPLETED
Gastrointestinal Dysfunction in Children Affected With Mitochondrial Disorders	nan	COMPLETED
The Natural History of Mitochondrial Diseases	nan	RECRUITING
Abnormalities in the Effects of Insulin and Exercise on Glucose- and Lipid Metabolism in Obesity and Type 2 Diabetes	nan	COMPLETED
Genetic Diagnosis in Inborn Errors of Metabolism	nan	ENROLLING_BY_INVITATION
Mitigating Mitochondrial RNA Release During Aging to Control Inflammation and Senescence	nan	NOT_YET_RECRUITING
Exercise Training Effects on Muscle Function in Adults With Mitochondrial Myopathy	nan	RECRUITING
The Genetics of Diabetes in Southern California Chinese Americans	nan	WITHDRAWN
Nicotinamide Riboside and Mitochondrial Biogenesis	nan	COMPLETED

Related proteins — ESM-2 sequence neighbours (a ATP5PD binder may also engage these)

Protein	Name	Similarity
P31399	—	1.000	P31399 →
P13620	—	0.997	P13620 →
Q9DCX2	—	0.995	Q9DCX2 →
P0C2C8	—	0.993	P0C2C8 →
Q24251	—	0.992	Q24251 →
Q7SI16	—	0.990	Q7SI16 →
Q6CFH9	—	0.988	Q6CFH9 →
O94390	—	0.987	O94390 →
P30902	—	0.986	P30902 →
O13350	—	0.986	O13350 →
C0HK60	—	0.983	C0HK60 →
P34748	—	0.981	P34748 →
P02721	—	0.980	P02721 →
Q8SPH6	—	0.979	Q8SPH6 →
P18859	—	0.978	P18859 →
O93980	—	0.978	O93980 →
Q0VFC7	—	0.977	Q0VFC7 →
P21571	—	0.977	P21571 →
Q9FT52	—	0.977	Q9FT52 →
Q1L987	—	0.976	Q1L987 →
P97450	—	0.976	P97450 →
P13618	—	0.975	P13618 →
Q6PBU7	—	0.974	Q6PBU7 →
Q9DGQ7	—	0.974	Q9DGQ7 →
O94373	—	0.974	O94373 →
Q24407	—	0.973	Q24407 →
P82925	—	0.973	P82925 →
ATP5PB	ATP synthase peripheral stalk subunit b, mitochondrial	0.973	landscape →
Q66JD1	—	0.973	Q66JD1 →
Q8RWA7	—	0.973	Q8RWA7 →