ATP5PD — 23 ClinVar variants
All ClinVar germline ATP5PD variants across every classification, each assembled from ClinVar, gnomAD, AlphaMissense, conservation and more. 23 flagged for review →
23 Uncertain significance
Full ATP5PD gene report on Sugi Atlas → Gene function, pathways, protein structure, constraint & interactions⚑ Evidence disagreements 23
Variants where the independent computational evidence doesn't line up with the clinical picture — a QC signal for a second look, not a reclassification.
Predictors lean, ClinVar uncertain 7
ClinVar classifies these uncertain (VUS), but the independent predictors unanimously lean one way — a triage signal for review, not a reclassification.
- ATP5PD p.Ala102Thr Uncertain significance Single submitter
- ATP5PD p.Ile19Val Uncertain significance Single submitter
- ATP5PD p.Ile20Val Uncertain significance Single submitter
- ATP5PD p.Ile27Thr Uncertain significance Single submitter
- ATP5PD p.Thr87Ala Uncertain significance Single submitter
- ATP5PD p.Tyr86Cys Uncertain significance Single submitter
- ATP5PD p.Val81Met Uncertain significance Single submitter
Predictors split 16
The independent predictors disagree with each other — read with care.
- ATP5PD p.Ala110Val Uncertain significance Single submitter
- ATP5PD p.Ala59Asp Uncertain significance Single submitter
- ATP5PD p.Asp129Val Uncertain significance Single submitter
- ATP5PD p.Glu18Asp Uncertain significance Single submitter
- ATP5PD p.Glu93Lys Uncertain significance Single submitter
- ATP5PD p.His155Pro Uncertain significance Single submitter
- ATP5PD p.Ile133Thr Uncertain significance Single submitter
- ATP5PD p.Ile52Val Uncertain significance Single submitter
- ATP5PD p.Leu136Phe Uncertain significance Single submitter
- ATP5PD p.Lys25Glu Uncertain significance Single submitter
- ATP5PD p.Lys63Arg Uncertain significance Single submitter
- ATP5PD p.Lys72Asn Uncertain significance Single submitter
- ATP5PD p.Pro151Leu Uncertain significance Single submitter
- ATP5PD p.Tyr115Ser Uncertain significance Single submitter
- ATP5PD p.Val105Ala Uncertain significance Single submitter
- ATP5PD p.Val79Phe Uncertain significance Single submitter
All ATP5PD variants
Uncertain significance 23
- p.Ala102Thr Single submitter ⚠
- p.Ala110Val Single submitter ⚠
- p.Ala59Asp Single submitter ⚠
- p.Asp129Val Single submitter ⚠
- p.Glu18Asp Single submitter ⚠
- p.Glu93Lys Single submitter ⚠
- p.His155Pro Single submitter ⚠
- p.Ile133Thr Single submitter ⚠
- p.Ile19Val Single submitter ⚠
- p.Ile20Val Single submitter ⚠
- p.Ile27Thr Single submitter ⚠
- p.Ile52Val Single submitter ⚠
- p.Leu136Phe Single submitter ⚠
- p.Lys25Glu Single submitter ⚠
- p.Lys63Arg Single submitter ⚠
- p.Lys72Asn Single submitter ⚠
- p.Pro151Leu Single submitter ⚠
- p.Thr87Ala Single submitter ⚠
- p.Tyr115Ser Single submitter ⚠
- p.Tyr86Cys Single submitter ⚠
- p.Val105Ala Single submitter ⚠
- p.Val79Phe Single submitter ⚠
- p.Val81Met Single submitter ⚠