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BMP6

Bone morphogenetic protein 6 · P22004 · BMP6 on Sugi Atlas →

323 patent compounds predicted against BMP6, 284 high-confidence (nearest known ligand ≥ 0.5)

Top predicted compounds (top 20 by supporting neighbours, then confidence)

CompoundConfidenceSupporting neighbours
Fondaparinux Fondaparinux (SCHEMBL4937) 0.65 1/20
SCHEMBL31087042 SCHEMBL31087042 0.60 1/20
SCHEMBL8401302 SCHEMBL8401302 0.50 1/20
Potassium Ion Potassium Ion (SCHEMBL17091477) 0.50 1/20
Potassium Ion Potassium Ion (SCHEMBL17091479) 0.50 1/20
SCHEMBL18947591 SCHEMBL18947591 0.49 1/20
SCHEMBL29386492 SCHEMBL29386492 0.49 1/20
SCHEMBL8401597 SCHEMBL8401597 0.49 1/20
SCHEMBL15452228 SCHEMBL15452228 0.48 1/20
SCHEMBL15452257 SCHEMBL15452257 0.48 1/20
SCHEMBL15452260 SCHEMBL15452260 0.48 1/20
SCHEMBL15452278 SCHEMBL15452278 0.48 1/20
SCHEMBL17771212 SCHEMBL17771212 0.48 1/20
SCHEMBL17771214 SCHEMBL17771214 0.48 1/20
SCHEMBL18177564 SCHEMBL18177564 0.48 1/20
SCHEMBL18177566 SCHEMBL18177566 0.48 1/20
SCHEMBL17000133 SCHEMBL17000133 0.48 1/20
SCHEMBL18350664 SCHEMBL18350664 0.48 1/20
SCHEMBL29383445 SCHEMBL29383445 0.48 1/20
SCHEMBL17167238 SCHEMBL17167238 0.47 1/20

Clinical trials — most relevant to BMP6 by text similarity (a relevance ranking, not an exhaustive list)

TrialPhaseStatus
Vitamin D and Carboxy PTH Fragments in Coronary Calcification PHASE4WITHDRAWN
Socket Augmentation Using Atorvastatin With Or Without PRGF (Clinical and Histomorphometric Study) PHASE4COMPLETED
A Multi-center, Comparative Clinical Trial to Evaluate the Efficacy and Safety of Inject BMP in Patients Undergoing Transforaminal Lumbar Interbody Fusion PHASE3UNKNOWN
A Study to Evaluate the Safety and Efficacy of Vactosertib and Imatinib in Patients With Advanced Desmoid Tumor PHASE1/PHASE2COMPLETED
The Use of Adhesion Molecule Loaded Hydrogel With Minimally Invasive Surgical Technique in Treatment of Periodontal Intrabony Defect PHASE1/PHASE2COMPLETED
Effects of Acute Estrogen Therapy on Bone Formation PHASE1COMPLETED
Short-term Impact of Cyplexinol® on Self-reported Joint Pain nanCOMPLETED
Role of Novel Biomarkers Associated With In-stent Restenosis After Percutaneous Coronary Intervention nanUNKNOWN
Study of Tissue, Blood, and Urine Samples From Patients With Advanced Prostate Cancer nanUNKNOWN
Immediate Implants in Maxillary Premolar Region Using Xenograft vs Allograft nanUNKNOWN
Induce XT™ Bone Graft in Foot and Ankle Fusion nanENROLLING_BY_INVITATION
Physiopathology of Pulmonary Arterial Hypertension: Mechanistic Studies nanUNKNOWN
Genes-in-Action - Hepcidin Regulation of Iron Supplementation nanCOMPLETED
AO CSH Mainstream Study on Cervical Spine Degeneration nanNOT_YET_RECRUITING
Genetic and Environmental Characteristics of Primary Pulmonary Hypertension nanCOMPLETED
Serum Sclerostin Levels, Cardiovascular Parameters and Carpal Tunnel Syndrome in Maintenance Hemodialysis Patients nanUNKNOWN
Effect of BMPR-2 Gene Mutations on Hemodynamic Response by Iloprost Inhalation in Pulmonary Arterial Hypertension nanCOMPLETED
The OsteoStrand Plus Deformity Study nanUNKNOWN
Osteogenic Effects in Human Mesenchymal Stem Cells Enhanced by Wnt Signaling nanCOMPLETED
Bone Markers and Bone Density Changes in Hyperperparathyroid Dialysis Patients Under Cinacalcet Treatment nanCOMPLETED
StratosPHere (Non-interventional Study) nanCOMPLETED
Assessment of Guided Bone Regeneration in Atrophic Anterior Maxilla nanUNKNOWN
Assessment of the TGF-beta Pathway and Micro-RNA in Pediatric Pulmonary Arterial Hypertension nanUNKNOWN
Osteogenic Profiling of Normal Calvarial Bone nanCOMPLETED
Exhaled Breath Olfactory Signature of Pulmonary Arterial Hypertension nanCOMPLETED
Therapeutic Irrigation Procedures to Treat Apical Periodontitis nanCOMPLETED
Osteocel® Plus in eXtreme Lateral Interbody Fusion (XLIF®) nanCOMPLETED
ABM/P-15 Bone Graft vs Traditional Bone Graft in Adult Spinal Deformity Surgery nanCOMPLETED
Importance of Neurogenic Inflammation in the Angiogenic Response of the Dental Pulp as a Defensive Response nanCOMPLETED
Evaluation of the Osteoinductivity of Atorvastatin Combined With β-TCP nanNOT_YET_RECRUITING

Related proteins — ESM-2 sequence neighbours (a BMP6 binder may also engage these)

ProteinNameSimilarity
P20722 — 1.000 P20722 →
Q04906 — 0.998 Q04906 →
P17491 — 0.997 P17491 →
Q04999 — 0.995 Q04999 →
P42917 — 0.993 P42917 →
P27093 — 0.991 P27093 →
P18075 — 0.989 P18075 →
P04088 — 0.988 P04088 →
Q07105 — 0.988 Q07105 →
P09529 — 0.988 P09529 →
P55105 — 0.987 P55105 →
O77681 — 0.987 O77681 →
P23359 — 0.987 P23359 →
Q7Z5Y6 — 0.986 Q7Z5Y6 →
P49003 — 0.986 P49003 →
Q9GK68 — 0.986 Q9GK68 →
Q66NC0 — 0.986 Q66NC0 →
P22003 — 0.986 P22003 →
Q7T2X7 — 0.985 Q7T2X7 →
O60383 — 0.985 O60383 →
Q9Z1W4 — 0.984 Q9Z1W4 →
P55108 — 0.984 P55108 →
Q08DX6 — 0.983 Q08DX6 →
P09531 — 0.983 P09531 →
Q7T2X6 — 0.983 Q7T2X6 →
Q96S42 — 0.983 Q96S42 →
A9CB18 — 0.983 A9CB18 →
P34821 — 0.982 P34821 →
Q91619 — 0.982 Q91619 →
P34820 — 0.982 P34820 →