SCHEMBL17000133

SCHEMBL17000133

CCCO[C@@H]1OC(C(=O)O)[C@@H](O[C@H]2OC(CO)[C@@H](O[C@@H]3OC(C(=O)O)[C@@H](O)C(O)[C@@H]3O)[C@H](O)C2NC(C)=O)C(O)[C@@H]1O

nearest known ligand 0.57

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LGALS3 P17931 3/20 0.57
LGALS8 O00214 2/20 0.57
LGALS4 P56470 2/20 0.57
MDK P21741 5/20 0.52
BDNF P23560 3/20 0.52
PTN P21246 2/20 0.52
BMP2 P12643 2/20 0.49
VEGFA P15692 2/20 0.49
CXCL12 P48061 2/20 0.49
SHH Q15465 2/20 0.49
IFNG P01579 1/20 0.48
PF4 P02776 1/20 0.48
CCL2 P13500 1/20 0.48
SELP P16109 1/20 0.48
BMP6 P22004 1/20 0.48
CCL11 P51671 1/20 0.48
WNT3A P56704 1/20 0.48
SELPLG Q14242 1/20 0.48
MAPK1 P28482 1/20 0.48
FGF1 P05230 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18494404 0.92 LGALS3 (0.56) LGALS3LGALS8LGALS4MDKBDNF
SCHEMBL16063765 0.86 LGALS8 (0.58) LGALS3LGALS8LGALS4MDKBDNF
SCHEMBL20180333 0.86 LGALS8 (0.58) LGALS3LGALS8LGALS4MDKBDNF
SCHEMBL17849726 0.86 LGALS3 (0.53) LGALS3LGALS8LGALS4MDKBDNF
SCHEMBL17001596 0.85 FGF1 (0.50) LGALS3LGALS8LGALS4MDKBDNF
SCHEMBL17001562 0.85 FGF1 (0.50) LGALS3LGALS8LGALS4MDKBDNF
SCHEMBL18494405 0.85 LGALS3 (0.53) LGALS3LGALS8LGALS4MDKBDNF
SCHEMBL16063647 0.85 LGALS3 (0.53) LGALS3LGALS8LGALS4MDKBDNF
SCHEMBL18494820 0.85 LGALS3 (0.53) LGALS3LGALS8LGALS4MDKBDNF
SCHEMBL17167287 0.84 MDK (0.50) LGALS3LGALS8LGALS4MDKBDNF

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20150224203-A1 Factor VIII Conjugates NOVO NORDISK A/S (DK) 2015-08-13 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20150224203-A1 Factor VIII Conjugates F8, F13B, F13A1 LGALS3 2320/4885LGALS8 919/4885LGALS4 2059/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.