DPAGT1

UDP-N-acetylglucosamine--dolichyl-phosphate N-acetylglucosaminephosphotransferase · Q9H3H5 · DPAGT1 on Sugi Atlas →

642 patent compounds predicted against DPAGT1, 442 high-confidence (nearest known ligand ≥ 0.5)

Top predicted compounds (top 20 by supporting neighbours, then confidence)

CompoundConfidenceSupporting neighbours
SCHEMBL24164783 SCHEMBL24164783 0.89 6/20
SCHEMBL24165556 SCHEMBL24165556 0.89 6/20
SCHEMBL26628858 SCHEMBL26628858 0.89 6/20
SCHEMBL26628860 SCHEMBL26628860 0.89 6/20
SCHEMBL26742327 SCHEMBL26742327 0.89 6/20
SCHEMBL26628854 SCHEMBL26628854 0.79 6/20
SCHEMBL26628856 SCHEMBL26628856 0.79 6/20
SCHEMBL32681957 SCHEMBL32681957 0.74 6/20
SCHEMBL14598984 SCHEMBL14598984 0.72 6/20
SCHEMBL13618329 SCHEMBL13618329 0.71 6/20
SCHEMBL13618320 SCHEMBL13618320 0.65 6/20
SCHEMBL26741959 SCHEMBL26741959 0.65 6/20
SCHEMBL26741960 SCHEMBL26741960 0.65 6/20
SCHEMBL24164786 SCHEMBL24164786 0.61 6/20
SCHEMBL24165043 SCHEMBL24165043 0.61 6/20
SCHEMBL14628987 SCHEMBL14628987 0.61 6/20
SCHEMBL14628971 SCHEMBL14628971 0.61 6/20
SCHEMBL32681956 SCHEMBL32681956 0.60 6/20
Capuramycin Capuramycin (SCHEMBL14598937) 0.92 5/20
Capuramycin Capuramycin (SCHEMBL15472874) 0.92 5/20

Clinical trials — most relevant to DPAGT1 by text similarity (a relevance ranking, not an exhaustive list)

TrialPhaseStatus
Vaccine Treatment for Advanced Non-Small Cell Lung Cancer PHASE1/PHASE2COMPLETED
The Effect of Triheptanoin on Fatty Acid Oxidation and Exercise Tolerance in Patients With Glycogenoses PHASE2COMPLETED
A Phase 1/2 Study of Intravenous Gene Transfer With an AAV9 Vector Expressing Human Beta-galactosidase in Type I and Type II GM1 Gangliosidosis PHASE1/PHASE2RECRUITING
Open-Label Extension Study to Assess GLM101 in PMM2-CDG Patients PHASE2ENROLLING_BY_INVITATION
Peptide Vaccine Focusing on Prevention of the Recurrence for Bladder Cancer PHASE2UNKNOWN
Effect of Gemfibrozil on Serum Glycosylphosphatidylinositol (GPI) Phospholipase D and Triglycerides PHASE1COMPLETED
Novel Peptide Vaccination for Patients With Advanced Bladder Cancer PHASE1COMPLETED
A Study of the Tolerance, Safety, and Pharmacokinetics of GNR-055 in Healthy Volunteers PHASE1COMPLETED
A Phase 1 Multiple Ascending Dose Study to Evaluate the Safety, Tolerability, and Pharmacokinetics of ManNAc in Subjects With Primary Podocyte Diseases PHASE1COMPLETED
Genome Environment Microbiome and Metabolome in Autism Study nanCOMPLETED
Glycosylation in Patients With Galactosaemia nanCOMPLETED
Celiac Disease Genomic Environmental Microbiome and Metabolomic Study nanRECRUITING
Clinical and Genetic Evaluation of Individuals With Undiagnosed Disorders Through the Undiagnosed Diseases Network nanRECRUITING
Evaluation of Blood Protein O-GlcNAcylation Levels in Children nanRECRUITING
Biomarker for Mucolipidosis Disorder Type I, II, III, IV (BioML) nanWITHDRAWN
Genetic Studies of Lysosomal Storage Disorders nanENROLLING_BY_INVITATION
Identification and Characterization of Monogenic Diabetes nanCOMPLETED
Personalised Therapeutics @LUMC nanACTIVE_NOT_RECRUITING
Using D-Galactose as a Food Supplement in Congenital Disorders of Glycosylation nanCOMPLETED
Incidence and Consequences of Disorders of Glycosylation in Patients With Conotruncal and Septal Heart Defects nanUNKNOWN
Genetics and Psychopathology in the 22q11 Deletion Syndrome nanUNKNOWN
Institution of an Italian Multicenter Database of Patients Affected by Diseases of Phosphate Metabolism nanNOT_YET_RECRUITING
Chest Wall Deformities in Children - Epidemiological Data nanCOMPLETED
Using Next-generation Sequencing in the Diagnosis of Epilepsy and/or Intellectual Disability in a Pediatric Cohorte nanCOMPLETED
Markers and Mechanisms of Macrovascular Disease in IDDM nanCOMPLETED
Genetic Analyses of Nonsyndromic and Syndromic Deafness in Pakistan nanENROLLING_BY_INVITATION
Genetic Bases of Neuroendocrine Neoplasms in Mexican Patients nanRECRUITING
A Retrospective Study to Identify New Omics Biomarkers of Chronic/Persistent Low Back Pain nanCOMPLETED
EXpanding Prenatal Cell Free DNA Screening Across moNogenic Disorders (EXPAND) nanRECRUITING
The Natural History of Sialidosis Type I nanRECRUITING

Related proteins — ESM-2 sequence neighbours (a DPAGT1 binder may also engage these)

ProteinNameSimilarity
P24140 1.000 P24140 →
P42867 1.000 P42867 →
Q5EA65 1.000 Q5EA65 →
P23338 1.000 P23338 →
Q6AXM5 0.963 Q6AXM5 →
Q8BGS7 0.962 Q8BGS7 →
CEPT1 Choline/ethanolaminephosphotransferase 1 0.962 landscape →
Q7ZYQ3 0.960 Q7ZYQ3 →
Q5ZKD1 0.958 Q5ZKD1 →
Q28H54 0.957 Q28H54 →
Q99L43 0.952 Q99L43 →
Q91XU8 0.952 Q91XU8 →
CDS2 Phosphatidate cytidylyltransferase 2 0.952 landscape →
SELENOI Ethanolaminephosphotransferase 1 0.951 landscape →
Q66H21 0.951 Q66H21 →
Q8C025 0.951 Q8C025 →
Q17QM4 0.950 Q17QM4 →
A0JNC1 0.947 A0JNC1 →
Q1LZE6 0.947 Q1LZE6 →
Q5ZHQ5 0.945 Q5ZHQ5 →
Q92903 0.945 Q92903 →
P49282 0.944 P49282 →
Q80TA1 0.944 Q80TA1 →
O35052 0.943 O35052 →
ZMPSTE24 CAAX prenyl protease 1 homolog 0.942 landscape →
P98191 0.942 P98191 →
Q5NV96 0.941 Q5NV96 →
Q8WUD6 0.941 Q8WUD6 →
Q9LDU6 0.940 Q9LDU6 →
Q4KLV1 0.940 Q4KLV1 →