CFL1

Cofilin-1 · P23528 · CFL1 on Sugi Atlas →

0 patent compounds predicted against CFL1, 0 high-confidence (nearest known ligand ≥ 0.5)

Top predicted compounds (top 20 by supporting neighbours, then confidence)

CompoundConfidenceSupporting neighbours

Clinical trials — most relevant to CFL1 by text similarity (a relevance ranking, not an exhaustive list)

TrialPhaseStatus
Ketamine Treatment Effects on Synaptic Plasticity in Depression PHASE4COMPLETED
Trial of Dasatinib (Sprycel®) in Subjects With Hormone-refractory Prostate Cancer PHASE2COMPLETED
LCL161 in Treating Patients With Primary Myelofibrosis, Post-Polycythemia Vera Myelofibrosis, or Post-Essential Thrombocytosis Myelofibrosis PHASE2COMPLETED
Biologic Correlative Taxotere/AC PHASE2COMPLETED
Interleukin-2 Treatment for Wiskott-Aldrich Syndrome PHASE1COMPLETED
Evaluating MED2005 & Nitrostat Bioavailability PHASE1COMPLETED
FAK Inhibitor in Patients With Advanced Solid Tumors PHASE1NOT_YET_RECRUITING
Gemcitabine and Dasatinib in Advanced Solid Tumors PHASE1COMPLETED
Studying the Role of Circulating Tumor Cell Clusters in Patients With High-risk Early Breast Cancer, Study GALIA nanRECRUITING
ADRB3, ROCK2 and GEF Levels in Overactive Bladder Patients nanCOMPLETED
Evaluation The Effect of NB-UVB and Methotrexate on The Level of Serum Gelsolin in Psoriatic Patients nanRECRUITING
Significance of Immunohistochemical Expression of Fascin-1 in Colorectal Carcinoma nanCOMPLETED
Investigate eNAMPT in Multiple Myeloma Biology and Establish Its Role in Disease Progression nanCOMPLETED
Predicting Postoperative Delirium Using EEG, Genetics and Neurobiomarkers of Cerebral Injury nanCOMPLETED
Add-on Pilot Trial of Minocycline to Treat Fragile X Syndrome nanCOMPLETED
Airway Smooth Muscle and Asthma Severity nanCOMPLETED
Blood-based Biomarkers for the Prognosis of Sports Related Concussion nanCOMPLETED
Investigating the Genetic Basis of Pseudoexfoliation Syndrome, Angle-closure Glaucoma and Primary Open-angle Glaucoma nanRECRUITING
Profiling Gingival Crevicular Fluid β-Catenin Level With 8-OHdG and Total Antioxidants Capacity During Healing of Periodontal Pockets: A 3-month Clinical Trial nanNOT_YET_RECRUITING
Mechanisms Underlying Local and Systemic Effects of Massage nanCOMPLETED
Genetic Study of Age-Related Macular Degeneration nanCOMPLETED
Circulating Markers for Ischemic Heart Disease nanRECRUITING
Study of the Pathophysiological Mechanisms Involved in Bleeding Events nanCOMPLETED
Relationship of Gestational Age and Urine Concentration of S100B in Preterm and Term Infants in the First Week of Life nanCOMPLETED
Cyclosporin A Therapy in Childhood Nephrotic Syndrome nanUNKNOWN
Role of Chemokine and Chemokine Receptor in Psoriasis nanWITHDRAWN
Predictive Value of E-cadherin, β-catenin and SOX4 in Recurrence and/or Progression of Non-muscle Invasive Urinary Bladder Transitional Cell Carcinoma. A Retrospective Study nanCOMPLETED
Effect of Low Dose of Colchicine on Platelet Reactivity nanCOMPLETED
Autoimmune Dysregulation in Pigmentary Glaucoma nanCOMPLETED
Urine Concentration of S100B in Extremely Premature Infants nanCOMPLETED

Related proteins — ESM-2 sequence neighbours (a CFL1 binder may also engage these)

ProteinNameSimilarity
P45592 1.000 P45592 →
Q6B7M7 1.000 Q6B7M7 →
Q5E9F7 1.000 Q5E9F7 →
Q4R5C0 1.000 Q4R5C0 →
P10668 1.000 P10668 →
P18760 1.000 P18760 →
Q5U4Y2 0.995 Q5U4Y2 →
Q5XHH8 0.995 Q5XHH8 →
P45591 0.986 P45591 →
P21566 0.985 P21566 →
Q5G6V9 0.983 Q5G6V9 →
Q148F1 0.982 Q148F1 →
Q9Y281 0.982 Q9Y281 →
Q5R6P6 0.963 Q5R6P6 →
P60984 0.961 P60984 →
P60983 0.961 P60983 →
Q56JZ9 0.960 Q56JZ9 →
Q63228 0.959 Q63228 →
P45695 0.958 P45695 →
GMFG Glia maturation factor gamma 0.957 landscape →
Q4I963 0.957 Q4I963 →
Q80T18 0.957 Q80T18 →
P45593 0.955 P45593 →
Q9CQI3 0.955 Q9CQI3 →
Q9ERL7 0.955 Q9ERL7 →
Q6BWX4 0.950 Q6BWX4 →
Q61316 0.947 Q61316 →
P60982 0.946 P60982 →
Q6CQ22 0.945 Q6CQ22 →
P18359 0.945 P18359 →