CMBL — patent landscape

Top predicted compounds (top 20 by supporting neighbours, then confidence)

	Compound	Confidence	Supporting neighbours

Clinical trials — most relevant to CMBL by text similarity (a relevance ranking, not an exhaustive list)

Trial	Phase	Status
A Trial of CM-AT in Children With Autism With All Levels of FCT (The Blum Study)	PHASE3	COMPLETED
The Safety and Immunogenicity of a TB Vaccine; MVA85A, in Healthy Volunteers Who Are Infected With HIV	PHASE1	COMPLETED
Biomarker for Mucolipidosis Disorder Type I, II, III, IV (BioML)	nan	WITHDRAWN
Identification of Genes Predisposing to Atherosclerosis	nan	COMPLETED
Respiratory Cathepsins, Proteases Inhibitors and Glycosaminoglycans (GAG) in Mucopolysaccharidosis	nan	COMPLETED
Impact of Seasonal Malaria Chemoprevention on Immunity Against Malaria Among Children in Northern Benin	nan	COMPLETED
Avapritinib in the Treatment of Unresectable or Recurrent Metastatic GIST Non-exon18 Mutations of PDGFRA	nan	RECRUITING
Primary Hyperoxaluria Mutation Genotyping/Phenotyping	nan	COMPLETED
SRT in Comparison to ERT on Immune Aspects and Bone Involvement in Gaucher Disease	nan	UNKNOWN
Lipa Gene Mutation in PED-LIPIGEN (Pediatric FH Subjects)	nan	UNKNOWN
Signs and Symptoms of Genetic Abnormalities Linked to Inherited Heart Disease	nan	COMPLETED
Screening of Lysosomal Storage Disorders Diseases in Minority Groups	nan	UNKNOWN
The Value of circRNAs (hsa_circ_0004001) in Early Diagnosis of HCC	nan	UNKNOWN
Markers and Mechanisms of Macrovascular Disease in IDDM	nan	COMPLETED
Chromosome 5Q Gene Variants and Asthma-Related Traits	nan	COMPLETED
The Natural History of Alpha-Mannosidosis	nan	COMPLETED
Clinical and Laboratory Study of Methylmalonic Acidemia	nan	RECRUITING
Gene-by-Smoking Interactions and Risk of Atherosclerosis - Ancillary to ARIC	nan	COMPLETED
Frequency of Pompe Disease in Patients With Myalgia With or Without Hyper Ckemia - Data From the Reference Center (CERCA)	nan	UNKNOWN
Sodium Transport: Genetics and Hypertension	nan	COMPLETED
Gene Expression of Endocannabinoid System in Episodic and Chronic Migraine Patients	nan	COMPLETED
Effect of Genetic Differences on Levels of Water Disinfection Byproducts in Blood After Showering	nan	COMPLETED
Genetic Variants and Regulation of Specialized Pro-resolving Mediator	nan	RECRUITING
Large-scale COVID-19 Population Screening	nan	UNKNOWN
Inflammatory/Familial Dilated Cardiomyopathy: Is There a Link to Autoimmune Diseases? TP9a	nan	COMPLETED
Celiac Disease Genomic Environmental Microbiome and Metabolomic Study	nan	RECRUITING
Molecular Genetics Study of Nasopharyngeal Carcinoma: Characterization of NCP Susceptibility Gene(s)	nan	COMPLETED
The Evaluation of Thiol Redox Status in Conjunctiva of Dry Eye Patients	nan	UNKNOWN
In Vivo Assessment of Histamine Pharmacodynamics	nan	WITHDRAWN
Identification of an Asthma Susceptibility Gene on 3P	nan	COMPLETED

Related proteins — ESM-2 sequence neighbours (a CMBL binder may also engage these)

Protein	Name	Similarity
Q5RBU3	—	1.000	Q5RBU3 →
Q7TP52	—	0.998	Q7TP52 →
Q8R1G2	—	0.996	Q8R1G2 →
Q5XH09	—	0.994	Q5XH09 →
Q6P7K0	—	0.993	Q6P7K0 →
Q6DHV7	—	0.961	Q6DHV7 →
Q0VC13	—	0.960	Q0VC13 →
Q8NFW8	—	0.959	Q8NFW8 →
Q5IH13	—	0.959	Q5IH13 →
Q9H6V9	—	0.959	Q9H6V9 →
A0A1P8AWH8	—	0.958	A0A1P8AWH8 →
Q80SY6	—	0.958	Q80SY6 →
Q94E75	—	0.956	Q94E75 →
Q5R6R5	—	0.956	Q5R6R5 →
Q9FQ11	—	0.955	Q9FQ11 →
Q3SZM5	—	0.955	Q3SZM5 →
Q0WUI9	—	0.954	Q0WUI9 →
Q5IH14	—	0.954	Q5IH14 →
Q6YXW6	—	0.954	Q6YXW6 →
Q504A5	—	0.954	Q504A5 →
P69060	—	0.953	P69060 →
Q90WG6	—	0.953	Q90WG6 →
Q90678	—	0.953	Q90678 →
Q5R7E8	—	0.953	Q5R7E8 →
PLAA	Phospholipase A-2-activating protein	0.952	landscape →
Q0E671	—	0.952	Q0E671 →
F4JP46	—	0.952	F4JP46 →
Q84WK4	—	0.952	Q84WK4 →
Q94AH8	—	0.952	Q94AH8 →
P23599	—	0.952	P23599 →