COPS8

COP9 signalosome complex subunit 8 · Q99627 · COPS8 on Sugi Atlas →

0 patent compounds predicted against COPS8, 0 high-confidence (nearest known ligand ≥ 0.5)

Top predicted compounds (top 20 by supporting neighbours, then confidence)

CompoundConfidenceSupporting neighbours

Clinical trials — most relevant to COPS8 by text similarity (a relevance ranking, not an exhaustive list)

TrialPhaseStatus
Treatment With HMG-COA Reductase Inhibitor of Growth and Bone Abnormalities in Children With Noonan Syndrome PHASE3COMPLETED
Addition of Everolimus to Standard of Care in Carcinoma Gallbladder PHASE2/PHASE3RECRUITING
Melpida: Recombinant Adeno-associated Virus (serotype 9) Encoding a Codon Optimized Human AP4M1 Transgene (hAP4M1opt) PHASE1/PHASE2RECRUITING
A Study to Test How Well BI 3000202 is Tolerated by People With Type 1 Interferonopathies PHASE1ACTIVE_NOT_RECRUITING
Temsirolimus and Sorafenib in Advanced Hepatocellular Carcinoma PHASE1COMPLETED
Glutamine Supplementation in People With Immune Dysregulation EARLY_PHASE1WITHDRAWN
Autophagy in Systemic Lupus Erythematosus nanUNKNOWN
Regulation of Lymphocyte Anti-tumor Response in Metastatic Patients Treated With the mTOR Inhibitor Everolimus nanCOMPLETED
Genetics of Endocrine Tumours - Familial Isolated Pituitary Adenoma - FIPA nanRECRUITING
Classification, Functional Stratification and Biomarkers in Ciliopathy (CILLICORIRCM) nanCOMPLETED
Genetic Analysis of Heart Channelopathies in Brazilian Patients and Their Relatives nanUNKNOWN
Inherited Reproductive Disorders nanRECRUITING
Identifying Genes and Mutations Underlying Retinitis Pigmentosa and Allied Diseases nanUNKNOWN
Growth Curves in Cockayne Syndrome Type 1 and Type 2 nanUNKNOWN
Implementation of Molecular Diagnostic Pathways nanUNKNOWN
Differential Gene Expression of Liver Tissue and Blood From Individuals With Chronic Viral Hepatitis nanUNKNOWN
Transcripts with Retained H/ACA Box SnoRNA Sequences As Biomarkers for Estrogen Dependence in Lum-B Breast Carcinomas nanACTIVE_NOT_RECRUITING
MEHMO Natural History and Biomarkers nanRECRUITING
Clinical, Genetic, and Epidemiologic Study of Children and Adults With RASopathies nanRECRUITING
Characterization of New Candidate Genes in Cases of Human Inherited Thrombocytopenia (CATCH) nanCOMPLETED
MERC Proteins in Saliva and GCF in Periodontal Disease (ELISA Study) nanCOMPLETED
Study of Constitutional Platelet Disease nanUNKNOWN
Genetic Analysis of Gray Platelet Syndrome nanCOMPLETED
Genetic Investigation of Cancer Predisposition nanNOT_YET_RECRUITING
Genetics of Familial and Sporadic ALS nanCOMPLETED
Biomarker Research in Inherited Movement Disorders nanRECRUITING
PCM1-JAK2 in Therapy Related Neoplasms nanUNKNOWN
The Influence of Genetic Variations in ELAPOR1 or ELAPOR2 on Insulin Secretion and Glucose Regulation in Humans nanUNKNOWN
The Molecular Basis of Inherited Reproductive Disorders nanACTIVE_NOT_RECRUITING
Identification of Genetic Basis of Atrioventricular Conduction Defects: From Congenital Forms to Degenerative Forms nanUNKNOWN

Related proteins — ESM-2 sequence neighbours (a COPS8 binder may also engage these)

ProteinNameSimilarity
Q5RF54 1.000 Q5RF54 →
Q8VBV7 1.000 Q8VBV7 →
Q6P4Z9 1.000 Q6P4Z9 →
Q6P637 0.978 Q6P637 →
Q5E964 0.973 Q5E964 →
PSMD13 26S proteasome non-ATPase regulatory subunit 13 0.972 landscape →
B0BN93 0.970 B0BN93 →
P84169 0.969 P84169 →
Q8RWF0 0.969 Q8RWF0 →
Q28C65 0.968 Q28C65 →
Q9WVJ2 0.968 Q9WVJ2 →
Q5ZLA5 0.968 Q5ZLA5 →
Q8GYA6 0.967 Q8GYA6 →
Q5R648 0.967 Q5R648 →
Q9CZW5 0.966 Q9CZW5 →
Q68FS2 0.965 Q68FS2 →
O88544 0.965 O88544 →
Q3SZA0 0.964 Q3SZA0 →
Q3T0V3 0.964 Q3T0V3 →
Q9DBZ5 0.964 Q9DBZ5 →
Q641X8 0.964 Q641X8 →
Q75Q39 0.963 Q75Q39 →
EIF3E Eukaryotic translation initiation factor 3 subunit E 0.963 landscape →
Q05AY2 0.962 Q05AY2 →
Q6P0H6 0.962 Q6P0H6 →
Q6P7L9 0.961 Q6P7L9 →
B5DGH9 0.961 B5DGH9 →
COPS4 COP9 signalosome complex subunit 4 0.961 landscape →
Q7ZUZ0 0.961 Q7ZUZ0 →
Q4R5E6 0.961 Q4R5E6 →