COPS4

COP9 signalosome complex subunit 4 · Q9BT78 · COPS4 on Sugi Atlas →

0 patent compounds predicted against COPS4, 0 high-confidence (nearest known ligand ≥ 0.5)

Top predicted compounds (top 20 by supporting neighbours, then confidence)

CompoundConfidenceSupporting neighbours

Clinical trials — most relevant to COPS4 by text similarity (a relevance ranking, not an exhaustive list)

TrialPhaseStatus
Treatment With HMG-COA Reductase Inhibitor of Growth and Bone Abnormalities in Children With Noonan Syndrome PHASE3COMPLETED
Addition of Everolimus to Standard of Care in Carcinoma Gallbladder PHASE2/PHASE3RECRUITING
Melpida: Recombinant Adeno-associated Virus (serotype 9) Encoding a Codon Optimized Human AP4M1 Transgene (hAP4M1opt) PHASE1/PHASE2RECRUITING
Ambroxol Therapy for Patients With Type 1 Gaucher Disease and Suboptimal Response to Enzyme Replacement Therapy PHASE2COMPLETED
Temsirolimus and Sorafenib in Advanced Hepatocellular Carcinoma PHASE1COMPLETED
A Study to Test How Well BI 3000202 is Tolerated by People With Type 1 Interferonopathies PHASE1ACTIVE_NOT_RECRUITING
Glutamine Supplementation in People With Immune Dysregulation EARLY_PHASE1WITHDRAWN
Autophagy in Systemic Lupus Erythematosus nanUNKNOWN
Regulation of Lymphocyte Anti-tumor Response in Metastatic Patients Treated With the mTOR Inhibitor Everolimus nanCOMPLETED
Genetics of Endocrine Tumours - Familial Isolated Pituitary Adenoma - FIPA nanRECRUITING
Classification, Functional Stratification and Biomarkers in Ciliopathy (CILLICORIRCM) nanCOMPLETED
MEHMO Natural History and Biomarkers nanRECRUITING
MERC Proteins in Saliva and GCF in Periodontal Disease (ELISA Study) nanCOMPLETED
Identifying Genes and Mutations Underlying Retinitis Pigmentosa and Allied Diseases nanUNKNOWN
Role of SF3B1 Mutation in Assessment of Acute and Chronic Lymphatic Leukemia nanNOT_YET_RECRUITING
Inherited Reproductive Disorders nanRECRUITING
Genetic Analysis of Heart Channelopathies in Brazilian Patients and Their Relatives nanUNKNOWN
Implementation of Molecular Diagnostic Pathways nanUNKNOWN
Characterization of New Candidate Genes in Cases of Human Inherited Thrombocytopenia (CATCH) nanCOMPLETED
Genetic Analysis of Gray Platelet Syndrome nanCOMPLETED
Study of Constitutional Platelet Disease nanUNKNOWN
Use of miRNAs in Growth Hormone Deficiency (GHD) nanUNKNOWN
Immune Cell Response to Stimuli nanRECRUITING
Whole-genome Sequencing Study in Patients With Diminished Ovarian Reserve nanUNKNOWN
Genetics of Familial and Sporadic ALS nanCOMPLETED
Muscle Tissue Bank for Muscular Dystrophy nanCOMPLETED
Chromosome 9 P Minus Syndrome nanRECRUITING
Genetic Analysis of Hereditary Disorders of Hearing and Balance nanCOMPLETED
ClinSeq: A Large-Scale Medical Sequencing Clinical Research Pilot Study nanACTIVE_NOT_RECRUITING
Phenotype/Genotype Correlations in Neuromuscular Disorders nanCOMPLETED

Related proteins — ESM-2 sequence neighbours (a COPS4 binder may also engage these)

ProteinNameSimilarity
Q5R648 1.000 Q5R648 →
Q68FS2 1.000 Q68FS2 →
O88544 1.000 O88544 →
Q3SZA0 1.000 Q3SZA0 →
Q4R5E6 1.000 Q4R5E6 →
A7Y521 1.000 A7Y521 →
Q6P0H6 0.998 Q6P0H6 →
Q8BG32 0.986 Q8BG32 →
F1QGH9 0.986 F1QGH9 →
Q5E964 0.983 Q5E964 →
F6XBL2 0.981 F6XBL2 →
Q94899 0.981 Q94899 →
Q9WVJ2 0.979 Q9WVJ2 →
F1LMZ8 0.979 F1LMZ8 →
Q2KI42 0.978 Q2KI42 →
PSMD11 26S proteasome non-ATPase regulatory subunit 11 0.978 landscape →
F6P3G4 0.978 F6P3G4 →
Q641X8 0.977 Q641X8 →
PSMD13 26S proteasome non-ATPase regulatory subunit 13 0.976 landscape →
EIF3E Eukaryotic translation initiation factor 3 subunit E 0.974 landscape →
P84169 0.973 P84169 →
GPS1 COP9 signalosome complex subunit 1 0.973 landscape →
B0BN93 0.972 B0BN93 →
Q2KJ46 0.972 Q2KJ46 →
Q5ZLA5 0.971 Q5ZLA5 →
PSMD3 26S proteasome non-ATPase regulatory subunit 3 0.971 landscape →
COPS8 COP9 signalosome complex subunit 8 0.969 landscape →
Q4R6G8 0.968 Q4R6G8 →
Q8RWF0 0.968 Q8RWF0 →
P60229 0.968 P60229 →