Sugi Predict
/ Targets
/ CUL5
Top predicted compounds (top 20 by supporting neighbours, then confidence)
| Compound | Confidence | Supporting neighbours |
|---|
Clinical trials — most relevant to CUL5 by text similarity (a relevance ranking, not an exhaustive list)
| Trial | Phase | Status |
|---|
| A Prospective, Placebo Controlled, Double-Blind, Cross-over Study on the Effects of a Probiotic Preparation (VSL#3) on Metabolic Profile, Intestinal Permeability, Microbiota, Cytokines and Chemokines Expression and Other Inflammatory Markers in Pediatric Patients With Crohn's Disease |
PHASE4 | UNKNOWN |
| Hypoxia-inducible Factor Prolyl Hydroxylase Inhibitors on Sarcopenia in Hemodialysis Patients |
PHASE4 | NOT_YET_RECRUITING |
| Can We Achieve 'high-quality' Weight Loss Through Supplementation and Exercise? the TRIM MUSCLE Study |
PHASE3 | COMPLETED |
| Effect of Deferoxamine on Wound Healing Rate in Patients With Diabetes Foot Ulcers |
PHASE2 | NOT_YET_RECRUITING |
| Phase II Study of Vandetanib in Individuals With Kidney Cancer |
PHASE2 | COMPLETED |
| Safety and Efficacy Study of Small Interfering RNA Molecule (Cand5) to Treat Diabetic Macular Edema |
PHASE2 | COMPLETED |
| Desferal Administration to Improve the Impaired Reaction to Hypoxia in Diabetes |
PHASE2 | UNKNOWN |
| Tianasen (ASO-GNAO1) for GNAO1-Encephalopathy With Epilepsy and Movement Disorders. |
PHASE1/PHASE2 | RECRUITING |
| A Phase II Study of Bevacizumab and Erlotinib in Subjects With Advanced Hereditary Leiomyomatosis and Renal Cell Cancer (HLRCC) or Sporadic Papillary Renal Cell Cancer |
PHASE2 | COMPLETED |
| PS-341 and Radiation to Treat Advanced Cancer of the Head and Neck |
PHASE1 | COMPLETED |
| Effect of Vorinostat on Nervous System Hemangioblastomas in Von Hippel-Lindau Disease (Missense Mutation Only) |
PHASE1 | COMPLETED |
| Impact of Nrf2 Activation on Macrovascular, Microvascular & Leg Function & Walking Capacity in Peripheral Artery Disease |
EARLY_PHASE1 | RECRUITING |
| Novel Molecular Targets and Innovative Therapeutic Perspective in Medulloblastoma |
EARLY_PHASE1 | RECRUITING |
| The Role of RING Ubiquitin Ligases in Biologic and Oncologic Processes in Tissues of Mesenchymal Origin |
nan | UNKNOWN |
| ADAPT: Efficacy of a Dietary Supplement During and After Exercise |
nan | COMPLETED |
| Clinical Study of 68Ga-DOTA-BLP PET Imaging in Noninvasive Diagnosis of Malignant Tumors |
nan | NOT_YET_RECRUITING |
| Prognostic Value of Combined Approach Based on KEAP1/NFE2L2 Mutations and Pre-therapeutic FDG-PET/CT Radiomic Analysis in Advanced Non-small-cell Lung Cancer PDL1 ≥ 50% Treated With Pembrolizumab (PEMBROMIC) |
nan | UNKNOWN |
| Differential Gene Expression of Liver Tissue and Blood From Individuals With Chronic Viral Hepatitis |
nan | UNKNOWN |
| Assessment of Residual VHL Function in Tumors - Can it Predict the Patients' Individual Course of Disease? |
nan | UNKNOWN |
| Drivers of Hypoxia-induced Angiogenesis in Tumor Development |
nan | UNKNOWN |
| Endolymphatic Sac Tumors in a Population of Patients With Von Hippel-Lindau Disease:The Natural History and Pathobiology, and a Prospective Non-Randomized Clinical Trial of Hearing Preservation Surgery in Patients With Early Stage Endolymphatic Sac Tumors |
nan | COMPLETED |
| Autophagy in Systemic Lupus Erythematosus |
nan | UNKNOWN |
| Screening for Endolymphatic Sac Tumours (ELSTs) in Von Hippel-Lindau (vHL) Patients |
nan | RECRUITING |
| Mitochondrial Activity and Myosteatosis in the Cachexia of Cancers of the Upper Aerodigestive Tract |
nan | UNKNOWN |
| Genetics of Endocrine Tumours - Familial Isolated Pituitary Adenoma - FIPA |
nan | RECRUITING |
| Long Term Follow-Up of Patients With Mesothelioma and Individuals With Germline Mutations in BAP1 |
nan | RECRUITING |
| Characterization of Angelman Syndrome |
nan | COMPLETED |
| Natural History and Management of Pancreatic Lesions in Von Hippel-Lindau Disease |
nan | COMPLETED |
| Establishment of a Prospective Clinical-biological Database |
nan | RECRUITING |
| DDX3X Syndrome -The Seaver Autism Center for Research and Treatment is Characterizing DDX3X-related Neurodevelopmental Disorders Using Genetic, Medical, and Neuropsychological Measures. |
nan | COMPLETED |
Related proteins — ESM-2 sequence neighbours (a CUL5 binder may also engage these)