CYRIB

CYFIP-related Rac1 interactor B · Q9NUQ9 · CYRIB on Sugi Atlas →

0 patent compounds predicted against CYRIB, 0 high-confidence (nearest known ligand ≥ 0.5)

Top predicted compounds (top 20 by supporting neighbours, then confidence)

CompoundConfidenceSupporting neighbours

Clinical trials — most relevant to CYRIB by text similarity (a relevance ranking, not an exhaustive list)

TrialPhaseStatus
Study of Sorafenib and Docetaxel in Metastatic Prostate Cancer PHASE2COMPLETED
Simvastatin + Cetuximab/Irinotecan in K-ras Mutant Colorectal Cancer (CRC) PHASE2COMPLETED
Endothelial Dysfunction and Oxidative Stress in Children With Sleep Disordered Breathing. PHASE1/PHASE2COMPLETED
Salt-Sensitivity and Immunity Cell Activation PHASE1/PHASE2ACTIVE_NOT_RECRUITING
NOX-A12 in Combination With Bendamustine and Rituximab in Relapsed Chronic Lymphocytic Leukemia (CLL) PHASE2COMPLETED
FAK Inhibitor in Patients With Advanced Solid Tumors PHASE1NOT_YET_RECRUITING
Temsirolimus and Sorafenib in Advanced Hepatocellular Carcinoma PHASE1COMPLETED
NCF Gene & TNFSF4 in SLE Patients nanUNKNOWN
ADRB3, ROCK2 and GEF Levels in Overactive Bladder Patients nanCOMPLETED
Study of the Pathophysiological Mechanisms Involved in Bleeding Events nanCOMPLETED
NETs: Protection or Harm in Neonatal Inflammation or Infection nanRECRUITING
Neutrophils as Prognostic Factors in Granulomatosis With Polyangiitis (Formerly Named Wegener's Granulomatosis) nanCOMPLETED
Golimumab Effect in the Modulation of Gut Microbiota in Ulcerative Colitis nanCOMPLETED
Molecular Markers of Human Sperm Function nanWITHDRAWN
Autophagy in Systemic Lupus Erythematosus nanUNKNOWN
Regulation of Lymphocyte Anti-tumor Response in Metastatic Patients Treated With the mTOR Inhibitor Everolimus nanCOMPLETED
Study of an Early Parenting Intervention for Children With Genetic Abnormalities and Mental Health Problems nanCOMPLETED
Integrins and Protocadherins in Glutamatergic Circuits: Identification of Common Signaling Pathways and Molecular Targets in Anxiety and Major Depressive Disorders (GAPsy) nanUNKNOWN
Pilot Trial of Sirolimus/MEC in High Risk Acute Myelogenous Leukemia (AML) nanCOMPLETED
Acceptance and Commitment Therapy for Caregivers of Children With a RASopathy: An Internal Pilot Feasibility Study and Follow-up Randomized Controlled Trial nanRECRUITING
Genetic Characterization of Parkinson's Disease nanCOMPLETED
The Role of Programmed Death Ligand -1 (Pdl-1) in Lung Cancer nanCOMPLETED
Immune Cell Response to Stimuli nanRECRUITING
Expression of Markers Related to Mitochondrial Functionality in Carcinoma of the Urinary Bladder: Comparative Retrospective Analysis Between Recurrent Tumors (Non-responders) and Non-recurrent Tumors (Responders) After Intravesical Treatment With Chemotherapy or Immunotherapy nanUNKNOWN
Characterization of New Candidate Genes in Cases of Human Inherited Thrombocytopenia (CATCH) nanCOMPLETED
Effect of Adenovirus E1A Oncogene on DNA Replication Dynamics nanUNKNOWN
Value of MicroRNA30a in Philadelphia Positive Leukemic Patients nanUNKNOWN
Genetics and Psychopathology in the 22q11 Deletion Syndrome nanUNKNOWN
Blood-based Biomarkers for the Prognosis of Sports Related Concussion nanCOMPLETED
Pathological and Nuclear Medicine Factors for Prognosis in Lung Carcinoma nanCOMPLETED

Related proteins — ESM-2 sequence neighbours (a CYRIB binder may also engage these)

ProteinNameSimilarity
Q921M7 1.000 Q921M7 →
Q8BHZ0 1.000 Q8BHZ0 →
Q2KJI3 1.000 Q2KJI3 →
Q5ZI04 1.000 Q5ZI04 →
Q5R6L2 1.000 Q5R6L2 →
Q9H0Q0 1.000 Q9H0Q0 →
Q17QT7 1.000 Q17QT7 →
P42173 0.993 P42173 →
Q8C4Y3 0.993 Q8C4Y3 →
E1BGH8 0.992 E1BGH8 →
Q8WX92 0.992 Q8WX92 →
Q96N11 0.992 Q96N11 →
Q9Y113 0.991 Q9Y113 →
Q96SK2 0.991 Q96SK2 →
E1C2Z0 0.991 E1C2Z0 →
Q4V847 0.991 Q4V847 →
Q5MNV8 0.991 Q5MNV8 →
B1AUR6 0.991 B1AUR6 →
E9Q555 0.990 E9Q555 →
Q80UK8 0.990 Q80UK8 →
Q9VZM7 0.990 Q9VZM7 →
O08662 0.990 O08662 →
Q8T2H0 0.990 Q8T2H0 →
PI4KA Phosphatidylinositol 4-kinase alpha 0.989 landscape →
Q756C4 0.989 Q756C4 →
Q9VE34 0.989 Q9VE34 →
Q8R0A7 0.989 Q8R0A7 →
Q9XW10 0.989 Q9XW10 →
Q8BKX6 0.989 Q8BKX6 →
A7YY97 0.989 A7YY97 →