DNAJA1 — patent landscape

Top predicted compounds (top 20 by supporting neighbours, then confidence)

Compound	Confidence	Supporting neighbours
SCHEMBL7163233	0.80	2/20
SCHEMBL7163211	0.79	2/20
SCHEMBL7168719	0.78	2/20
SCHEMBL7160351	0.77	2/20
SCHEMBL7162913	0.73	2/20
SCHEMBL7160377	0.70	2/20
SCHEMBL7160573	0.70	2/20
SCHEMBL7163748	0.70	2/20
SCHEMBL7165539	0.69	2/20
SCHEMBL1434347	0.69	2/20
SCHEMBL7163775	0.68	2/20
SCHEMBL7167481	0.68	2/20
SCHEMBL7167930	0.68	2/20
SCHEMBL7177668	0.66	2/20
SCHEMBL7164897	0.64	2/20
SCHEMBL7165203	0.64	2/20
SCHEMBL7167942	0.64	2/20
SCHEMBL7159336	0.64	2/20
SCHEMBL7161773	0.62	2/20
SCHEMBL7164828	0.61	2/20

Clinical trials — most relevant to DNAJA1 by text similarity (a relevance ranking, not an exhaustive list)

Trial	Phase	Status
I/II Phase Study Evaluating M1774 in Combination With Fulvestrant in HR+ and HER2- Advanced Breast Cancers	PHASE1/PHASE2	NOT_YET_RECRUITING
Clinical Study of EBV-LMP1 Targeted DNAzyme to Treat Nasopharyngeal Carcinoma	PHASE1/PHASE2	COMPLETED
Study of Oral CNF2024 (BIIB021) in Advanced Solid Tumors	PHASE1	COMPLETED
Safety and Pharmacology of SNX-5422 Plus Carboplatin and Paclitaxel in Subjects With Solid Tumors	PHASE1	COMPLETED
AZD2281 and Cisplatin Plus Gemcitabine to Treat Solid Tumor Cancers	PHASE1	COMPLETED
Genetic Characterization of Parkinson's Disease	nan	COMPLETED
Mapping Novel Disease Genes for Dilated Cardiomyopathy	nan	COMPLETED
Genetic Analysis of Hereditary Disorders of Hearing and Balance	nan	COMPLETED
Identification of Genes and Pathogenesis Involved in Familial Thoracic Aortic Aneurysm	nan	COMPLETED
Better Delineation of DDX3X Related Phenotype and Epigenetic Signature.	nan	UNKNOWN
Genetic Variation in TRAF3IP2 (rs13190932)	nan	RECRUITING
Autophagy in Systemic Lupus Erythematosus	nan	UNKNOWN
Idiopathic Dilated Cardiomyopathy	nan	COMPLETED
A Study Providing Genetic Testing to Find Those Who May Have Primary Ciliary Dyskinesia for Potential Clinical Trials	nan	ACTIVE_NOT_RECRUITING
PCD New Gene Discovery	nan	COMPLETED
Natural History of Asphyxiating Thoracic Dystrophy (DTJ)	nan	COMPLETED
Genetics of Primary Ciliary Dyskinesia	nan	COMPLETED
Genetic of SportS Induced Endofibrotic Remodeling	nan	COMPLETED
Shwachman Diamond Syndrome Registry and Study	nan	RECRUITING
Relationship Between Genes Important in Blood Pressure Regulation and Blood Pressure Therapy in Hypertension	nan	COMPLETED
Genetic Analyses of Nonsyndromic and Syndromic Deafness in Pakistan	nan	ENROLLING_BY_INVITATION
Mayo AVC Registry and Biobank	nan	RECRUITING
Characterization of WAGR Syndrome and Other Chromosome 11 Gene Deletions	nan	COMPLETED
Exome Analysis in Hearing Impaired Patients	nan	UNKNOWN
Genetic Analysis of Familial Hypertrophic Cardiomyopathy	nan	COMPLETED
Nuclear Myosin VI - a Therapeutic Target in Breast Cancer	nan	UNKNOWN
Registry and Natural History Study for Early Onset Hereditary Spastic Paraplegia	nan	RECRUITING
Pathogenesis of Primary Ciliary Dyskinesia (PCD) Lung Disease	nan	RECRUITING
Genetics of Neonatal Encephalopathy and Related Disorders	nan	RECRUITING
Study of Individuals and Families With Aberrations in DDX41 or Similar Cancer Predisposition Variants	nan	RECRUITING

Related proteins — ESM-2 sequence neighbours (a DNAJA1 binder may also engage these)

Protein	Name	Similarity
Q5NVI9	—	1.000	Q5NVI9 →
P63036	—	1.000	P63036 →
Q5E954	—	1.000	Q5E954 →
Q95JF4	—	1.000	Q95JF4 →
DNAJA2	DnaJ homolog subfamily A member 2	1.000	landscape →
P63037	—	0.999	P63037 →
O35824	—	0.999	O35824 →
Q2HJ94	—	0.998	Q2HJ94 →
Q9JMC3	—	0.996	Q9JMC3 →
Q9QYJ0	—	0.996	Q9QYJ0 →
Q8WW22	—	0.994	Q8WW22 →
P43644	—	0.992	P43644 →
Q04960	—	0.992	Q04960 →
Q94AW8	—	0.991	Q94AW8 →
Q0JB88	—	0.991	Q0JB88 →
P25491	—	0.988	P25491 →
Q03363	—	0.988	Q03363 →
P42825	—	0.987	P42825 →
P42824	—	0.986	P42824 →
Q5R8J8	—	0.984	Q5R8J8 →
DNAJB11	DnaJ homolog subfamily B member 11	0.984	landscape →
O74752	—	0.984	O74752 →
P81999	—	0.983	P81999 →
Q3MI00	—	0.983	Q3MI00 →
Q3ZBA6	—	0.983	Q3ZBA6 →
B9FHF3	—	0.982	B9FHF3 →
Q9QYJ3	—	0.982	Q9QYJ3 →
P25685	—	0.982	P25685 →
Q9D832	—	0.981	Q9D832 →
Q99KV1	—	0.981	Q99KV1 →