EEF1A1

Elongation factor 1-alpha 1 · P68104 · EEF1A1 on Sugi Atlas →

20 patent compounds predicted against EEF1A1, 5 high-confidence (nearest known ligand ≥ 0.5)

Top predicted compounds (top 20 by supporting neighbours, then confidence)

CompoundConfidenceSupporting neighbours
SCHEMBL18022884 SCHEMBL18022884 0.35 2/20
SCHEMBL781368 SCHEMBL781368 0.45 1/20
SCHEMBL781369 SCHEMBL781369 0.45 1/20
SCHEMBL9755640 SCHEMBL9755640 0.41 1/20
SCHEMBL18022930 SCHEMBL18022930 0.40 1/20

Clinical trials — most relevant to EEF1A1 by text similarity (a relevance ranking, not an exhaustive list)

TrialPhaseStatus
Everolimus for Children With Recurrent or Progressive Ependymoma PHASE2COMPLETED
Antiviral Activity and Safety of 3 Different Doses of Mifepristone in Hepatitis C Infected Patients PHASE2COMPLETED
Tianasen (ASO-GNAO1) for GNAO1-Encephalopathy With Epilepsy and Movement Disorders. PHASE1/PHASE2RECRUITING
Sirolimus Treatment in Patients With Autosomal Dominant Polycystic Kidney Disease: Renal Efficacy and Safety PHASE2COMPLETED
ISIS 183750 With Irinotecan for Advanced Solid Tumors or Colorectal Cancer PHASE1/PHASE2COMPLETED
PhII 5-Azacytidine Plus Valproic Acid and Eventually Atra in Intermediate II and High Risk MDS PHASE2COMPLETED
Study of Decitabine in Combination With Sequential Rapamycin or Ribavirin in High Risk AML Patients PHASE1/PHASE2COMPLETED
Effect of Deferoxamine on Wound Healing Rate in Patients With Diabetes Foot Ulcers PHASE2NOT_YET_RECRUITING
Temsirolimus and Sorafenib in Advanced Hepatocellular Carcinoma PHASE1COMPLETED
Endolymphatic Sac Tumors in a Population of Patients With Von Hippel-Lindau Disease:The Natural History and Pathobiology, and a Prospective Non-Randomized Clinical Trial of Hearing Preservation Surgery in Patients With Early Stage Endolymphatic Sac Tumors nanCOMPLETED
Effect of Branched Chain Amino Acids on Muscle nanCOMPLETED
EXtremely Early-onset Type 1 Diabetes EXtremely Early-onset Type 1 Diabetes (A Musketeers' Memorandum Study) nanRECRUITING
Role of Amino Acids and Genetic Disorder in Pathogenesis of Heart Failure nanUNKNOWN
Autophagy in Systemic Lupus Erythematosus nanUNKNOWN
Regulation of Lymphocyte Anti-tumor Response in Metastatic Patients Treated With the mTOR Inhibitor Everolimus nanCOMPLETED
Quantification of GADD34 Expression in RA nanCOMPLETED
MEHMO Natural History and Biomarkers nanRECRUITING
Effect of Adenovirus E1A Oncogene on DNA Replication Dynamics nanUNKNOWN
Longitudinal Biomarkers With Selected Outcome Measures In CMT nanRECRUITING
Rapamycin as a Means of Interference With Reconsolidation of Posttraumatic Stress Disorder-related Traumatic Memory nanCOMPLETED
Research on the Early and Prognosis Diagnosis of Vascular Dementia nanRECRUITING
EKLF Gene Expression in β-thalassemia nanNOT_YET_RECRUITING
CCM Italian Registry nanUNKNOWN
Effect of Non-chirurgical Periodontal Treatment on the Immune System From a Gender Perspective nanCOMPLETED
TranspulmonarY Estrogen Gradient and Estrogen Receptors (TYEGER) in PAH nanWITHDRAWN
Phenotypic and Genotypic Characterization of Subjects With Syndromic Obesity: Identifying New Candidate Genes by Exome Sequencing (OBEXOME) nanCOMPLETED
mTORC1 and Autophagy in Human Brown Adipocytes nanCOMPLETED
Genetics of Familial and Sporadic ALS nanCOMPLETED
Pilot Trial of Sirolimus/MEC in High Risk Acute Myelogenous Leukemia (AML) nanCOMPLETED
Speech and Short-term Memory Functions in Dyslexia: a Combined MEG and EEG Study nanUNKNOWN

Related proteins — ESM-2 sequence neighbours (a EEF1A1 binder may also engage these)

ProteinNameSimilarity
P68105 1.000 P68105 →
A2Q0Z0 1.000 A2Q0Z0 →
P02993 1.000 P02993 →
Q41011 1.000 Q41011 →
P25166 1.000 P25166 →
P62631 1.000 P62631 →
Q66RN5 1.000 Q66RN5 →
Q32PH8 1.000 Q32PH8 →
P10126 1.000 P10126 →
Q5R4R8 1.000 Q5R4R8 →
EEF1A2 Elongation factor 1-alpha 2 1.000 landscape →
Q01765 1.000 Q01765 →
Q00251 1.000 Q00251 →
Q9YIC0 1.000 Q9YIC0 →
P62629 1.000 P62629 →
Q96WZ1 1.000 Q96WZ1 →
P68103 1.000 P68103 →
O64937 1.000 O64937 →
P62632 1.000 P62632 →
P86934 1.000 P86934 →
Q2HJN4 1.000 Q2HJN4 →
Q5VTE0 1.000 Q5VTE0 →
Q8GTY0 1.000 Q8GTY0 →
O59949 1.000 O59949 →
A5DPE3 1.000 A5DPE3 →
P86939 1.000 P86939 →
Q59QD6 1.000 Q59QD6 →
P29521 1.000 P29521 →
Q5R1X2 1.000 Q5R1X2 →
Q41803 1.000 Q41803 →