EMC1

ER membrane protein complex subunit 1 · Q8N766 · EMC1 on Sugi Atlas →

0 patent compounds predicted against EMC1, 0 high-confidence (nearest known ligand ≥ 0.5)

Top predicted compounds (top 20 by supporting neighbours, then confidence)

CompoundConfidenceSupporting neighbours

Clinical trials — most relevant to EMC1 by text similarity (a relevance ranking, not an exhaustive list)

TrialPhaseStatus
Targeting Endoplasmic Reticulum Stress in Human Hypertension PHASE1/PHASE2RECRUITING
Melpida: Recombinant Adeno-associated Virus (serotype 9) Encoding a Codon Optimized Human AP4M1 Transgene (hAP4M1opt) PHASE1/PHASE2RECRUITING
Study of GnRH-A [Leuprorelin(Lorelin Depot] Plus Leterozole +/- Everolimus for Premenopausal Women With Metastatic Breast Cancer PHASE2COMPLETED
Pembrolizumab (MK-3475) in MM Patients With Residual Disease PHASE2COMPLETED
Ambroxol Therapy for Patients With Type 1 Gaucher Disease and Suboptimal Response to Enzyme Replacement Therapy PHASE2COMPLETED
Phase I Study of Novel Estrogen Receptor(ER) a36 Modifier Icaritin in Advanced Breast Cancer Patients PHASE1UNKNOWN
Novel Peptide Vaccination for Patients With Advanced Bladder Cancer PHASE1COMPLETED
PBA Use for Treatment of ATF6-/- Patients EARLY_PHASE1SUSPENDED
Dynamics of Muscle Mitochondria in Type 2 Diabetes (DYNAMMO T2D) EARLY_PHASE1COMPLETED
Quantification of GADD34 Expression in RA nanCOMPLETED
Regulation of Lymphocyte Anti-tumor Response in Metastatic Patients Treated With the mTOR Inhibitor Everolimus nanCOMPLETED
MERC Proteins in Saliva and GCF in Periodontal Disease (ELISA Study) nanCOMPLETED
Autophagy in Systemic Lupus Erythematosus nanUNKNOWN
Hydroxychloroquin (HCQ) in chILD of Genetic Defect nanCOMPLETED
The Influence of Genetic Variations in ELAPOR1 or ELAPOR2 on Insulin Secretion and Glucose Regulation in Humans nanUNKNOWN
Dynamics of Muscle Mitochondria in Type 2 Diabetes Exercise nanCOMPLETED
Nuclear Myosin VI - a Therapeutic Target in Breast Cancer nanUNKNOWN
Mayo AVC Registry and Biobank nanRECRUITING
Maternal Genes and Epimutations: Beckwith-Wiedemann Syndrome & Reproductive Risks nanRECRUITING
Characterization of New Candidate Genes in Cases of Human Inherited Thrombocytopenia (CATCH) nanCOMPLETED
Muscle Tissue Bank for Muscular Dystrophy nanCOMPLETED
MEHMO Natural History and Biomarkers nanRECRUITING
Identifying Genes and Mutations Underlying Retinitis Pigmentosa and Allied Diseases nanUNKNOWN
Study of Constitutional Platelet Disease nanUNKNOWN
Identification of New Candidate Genes in Patients With Mitochondrial Disease by High Resolution Chromosome Analysis on DNA Chip nanCOMPLETED
Whole Exome and Whole Genome Sequencing for Genotyping of Inherited and Congenital Eye Conditions nanRECRUITING
Mapping Novel Disease Genes for Dilated Cardiomyopathy nanCOMPLETED
sCD163 in ALS Patients nanCOMPLETED
Establishment of Human Cellular Disease Models for Wilson Disease nanCOMPLETED
Genetic Analysis of Heart Channelopathies in Brazilian Patients and Their Relatives nanUNKNOWN

Related proteins — ESM-2 sequence neighbours (a EMC1 binder may also engage these)

ProteinNameSimilarity
Q5ZL00 1.000 Q5ZL00 →
Q5R7K6 1.000 Q5R7K6 →
Q8C7X2 1.000 Q8C7X2 →
Q6NRB9 0.999 Q6NRB9 →
Q9EQY0 0.981 Q9EQY0 →
PIGS GPI-anchor transamidase component PIGS 0.981 landscape →
Q9EPU4 0.981 Q9EPU4 →
Q6PD26 0.980 Q6PD26 →
F1PCT7 0.980 F1PCT7 →
Q62181 0.979 Q62181 →
ERN1 Serine/threonine-protein kinase/endoribonuclease IRE1 0.979 landscape →
Q7ZVR1 0.979 Q7ZVR1 →
Q566H4 0.979 Q566H4 →
Q75ZY9 0.979 Q75ZY9 →
Q07DZ1 0.978 Q07DZ1 →
Q6DDG2 0.978 Q6DDG2 →
Q5R5N9 0.978 Q5R5N9 →
A0JP70 0.978 A0JP70 →
Q2QLA9 0.978 Q2QLA9 →
O42236 0.978 O42236 →
Q108U6 0.978 Q108U6 →
Q4ADV7 0.978 Q4ADV7 →
Q5ZJH2 0.978 Q5ZJH2 →
Q6DFC6 0.977 Q6DFC6 →
A0A0R4IVV0 0.977 A0A0R4IVV0 →
Q9ESW0 0.977 Q9ESW0 →
Q7Z4N8 0.977 Q7Z4N8 →
O88307 0.977 O88307 →
O00423 0.977 O00423 →
Q09YK0 0.977 Q09YK0 →