EMC2

ER membrane protein complex subunit 2 · Q15006 · EMC2 on Sugi Atlas →

0 patent compounds predicted against EMC2, 0 high-confidence (nearest known ligand ≥ 0.5)

Top predicted compounds (top 20 by supporting neighbours, then confidence)

CompoundConfidenceSupporting neighbours

Clinical trials — most relevant to EMC2 by text similarity (a relevance ranking, not an exhaustive list)

TrialPhaseStatus
Melpida: Recombinant Adeno-associated Virus (serotype 9) Encoding a Codon Optimized Human AP4M1 Transgene (hAP4M1opt) PHASE1/PHASE2RECRUITING
Targeting Endoplasmic Reticulum Stress in Human Hypertension PHASE1/PHASE2RECRUITING
Tamoxifen in Patients With Oesophageal Cancer PHASE1UNKNOWN
PBA Use for Treatment of ATF6-/- Patients EARLY_PHASE1SUSPENDED
Bristol-Myers Squibb Dasatinib Src Inhibition in Endometrial Cancer EARLY_PHASE1COMPLETED
Quantification of GADD34 Expression in RA nanCOMPLETED
MERC Proteins in Saliva and GCF in Periodontal Disease (ELISA Study) nanCOMPLETED
Regulation of Lymphocyte Anti-tumor Response in Metastatic Patients Treated With the mTOR Inhibitor Everolimus nanCOMPLETED
MEHMO Natural History and Biomarkers nanRECRUITING
Hydroxychloroquin (HCQ) in chILD of Genetic Defect nanCOMPLETED
Autophagy in Systemic Lupus Erythematosus nanUNKNOWN
The Influence of Genetic Variations in ELAPOR1 or ELAPOR2 on Insulin Secretion and Glucose Regulation in Humans nanUNKNOWN
Prevalence of a Non-Expressing 11B Mutation in Aka Peoples of the Central African Republic nanCOMPLETED
Nuclear Myosin VI - a Therapeutic Target in Breast Cancer nanUNKNOWN
Human Epilepsy Genetics--Neuronal Migration Disorders Study nanRECRUITING
Maternal Genes and Epimutations: Beckwith-Wiedemann Syndrome & Reproductive Risks nanRECRUITING
Muscle Tissue Bank for Muscular Dystrophy nanCOMPLETED
Cerebellar Mutism Syndrome Study nanRECRUITING
Mayo AVC Registry and Biobank nanRECRUITING
Mapping Novel Disease Genes for Dilated Cardiomyopathy nanCOMPLETED
Genetic Analysis of Heart Channelopathies in Brazilian Patients and Their Relatives nanUNKNOWN
Genetic Analysis of Gray Platelet Syndrome nanCOMPLETED
Dynamics of Muscle Mitochondria in Type 2 Diabetes Exercise nanCOMPLETED
Evaluation of Serum Tumor Endothelial Marker1 as a Potential Biomarker for Colorectal Cancer Diagnosis and Cancer Progression nanNOT_YET_RECRUITING
Characterization of New Candidate Genes in Cases of Human Inherited Thrombocytopenia (CATCH) nanCOMPLETED
Biomarkers in SCOTland CardiomyopatHy Registry (Bio-SCOTCH) nanRECRUITING
Study of Constitutional Platelet Disease nanUNKNOWN
Clinical Study of 68Ga-DOTA-BLP PET Imaging in Noninvasive Diagnosis of Malignant Tumors nanNOT_YET_RECRUITING
Genetic Analysis of Inherited Urologic Malignant Disorders: Collection of Samples nanCOMPLETED
Establishment of Human Cellular Disease Models for Wilson Disease nanCOMPLETED

Related proteins — ESM-2 sequence neighbours (a EMC2 binder may also engage these)

ProteinNameSimilarity
Q5R882 1.000 Q5R882 →
Q5E993 1.000 Q5E993 →
B0BNG0 1.000 B0BNG0 →
Q9CRD2 1.000 Q9CRD2 →
Q6TGY8 1.000 Q6TGY8 →
Q5M7J9 0.989 Q5M7J9 →
Q8AVU9 0.985 Q8AVU9 →
Q6INS3 0.984 Q6INS3 →
CDC23 Cell division cycle protein 23 homolog 0.982 landscape →
Q8BGZ4 0.978 Q8BGZ4 →
GTF3C3 General transcription factor 3C polypeptide 3 0.977 landscape →
P85969 0.975 P85969 →
A1A4R8 0.974 A1A4R8 →
Q80UM3 0.974 Q80UM3 →
Q5KU39 0.973 Q5KU39 →
Q6N069 0.973 Q6N069 →
P49754 0.973 P49754 →
O89079 0.973 O89079 →
Q2KJ25 0.973 Q2KJ25 →
ANAPC7 Anaphase-promoting complex subunit 7 0.972 landscape →
Q9V345 0.972 Q9V345 →
CTR9 RNA polymerase-associated protein CTR9 homolog 0.972 landscape →
Q5RBI3 0.972 Q5RBI3 →
Q60445 0.972 Q60445 →
B3DNN5 0.972 B3DNN5 →
Q8VY89 0.971 Q8VY89 →
A7RWP6 0.971 A7RWP6 →
Q8VD72 0.971 Q8VD72 →
Q5R4J9 0.971 Q5R4J9 →
EIF3A Eukaryotic translation initiation factor 3 subunit A 0.971 landscape →