ERAL1

GTPase Era, mitochondrial · O75616 · ERAL1 on Sugi Atlas →

0 patent compounds predicted against ERAL1, 0 high-confidence (nearest known ligand ≥ 0.5)

Top predicted compounds (top 20 by supporting neighbours, then confidence)

CompoundConfidenceSupporting neighbours

Clinical trials — most relevant to ERAL1 by text similarity (a relevance ranking, not an exhaustive list)

TrialPhaseStatus
Motor Function Efficacy of Pharmacological Treatments Targeting Energy Metabolism, in Parkinson's Patients PHASE4UNKNOWN
Cardioprotective Empagliflozin for Cancer Patients Receiving Doxorubicin PHASE2/PHASE3UNKNOWN
ONC201 in Recurrent/Refractory Metastatic Breast Cancer and Advanced Endometrial Carcinoma PHASE2COMPLETED
Mitochondrial Dysfunction in the Pathophysiology and Treatment of Bipolar Disorder PHASE2WITHDRAWN
Dynamics of Muscle Mitochondria in Type 2 Diabetes (DYNAMMO T2D) EARLY_PHASE1COMPLETED
Dynamics of Muscle Mitochondria in Type 2 Diabetes Exercise nanCOMPLETED
Nicotinamide Riboside and Mitochondrial Biogenesis nanCOMPLETED
Transgenerational Metabolic-Immune Biomarkers of Neurological and Neurodevelopmental Disorders nanRECRUITING
Drug Repurposing for Mitochondrial Disorders Using iPSCs Derived Neural Cells nanRECRUITING
Skeletal Muscle Regeneration in Survivors of Critical Illness: How to Prevent Satellite Cell Failure? nanRECRUITING
Measuring Protein Turnover in Humans Across the Lifespan by Metabolic Labeling With Deuterium Oxide nanRECRUITING
MERC Proteins in Saliva and GCF in Periodontal Disease (ELISA Study) nanCOMPLETED
Clinical Study of Hydroxytyrosol (HT) in Mitochondrial Diseases nanCOMPLETED
Mitoferrin-1 Expression in Erythropoietic Protoporphyria (Porphyria Rare Disease Clinical Research Consortium (RDCRC)) nanCOMPLETED
Tissue Sample Study for Mitochondrial Disorders nanENROLLING_BY_INVITATION
A Study Into the Underlying Biochemical Pathways Involved in Parkinson's Disease, Such as Mitochondrial (Cellular Powerhouse) Dysfunction nanCOMPLETED
Role of Sorcin and Annexin A3 in Breast Cancer Patients nanUNKNOWN
Human Mitochondrial Stress-driven Obesity Resistance nanCOMPLETED
Fatigue in Multiple Sclerosis and Its Relationship to Inflammatory and Neurodegenerative Markers of the Disease nanENROLLING_BY_INVITATION
Pathogenic Insights and Search for Biomarkers in RFC1-ataxia/CANVAS nanRECRUITING
Identification of Serum Level of Glutathione Peroxidase 4 nanNOT_YET_RECRUITING
Natural History Study of FDXR Mutation-related Mitochondriopathy nanCOMPLETED
Relationship Between Mitochondrial Dysfunction and Fatique in Cancer Patients Following External Beam Radiation Therapy nanCOMPLETED
Biological Aging Hallmarks-Guided Integrative TCM and Conventional Medicine in Post-Treatment Unexplained Female Infertility nanRECRUITING
Mitochondrial Dysfunctions Driving Insulin Resistance nanCOMPLETED
Lifestyle Intervention in Fatty Liver (NAFLD) nanUNKNOWN
Effect of Branched Chain Amino Acids on Muscle nanCOMPLETED
Mitigating Mitochondrial RNA Release During Aging to Control Inflammation and Senescence nanNOT_YET_RECRUITING
Mitochondrial Disease-associated ImmunoDeficiencies nanRECRUITING
Effect of Dietary Nitrate on Immobilization-induced Changes in Skeletal Muscle in Young Healthy Men nanRECRUITING

Related proteins — ESM-2 sequence neighbours (a ERAL1 binder may also engage these)

ProteinNameSimilarity
Q9CZU4 0.995 Q9CZU4 →
A5PK43 0.994 A5PK43 →
D2GU20 0.993 D2GU20 →
Q5EBA0 0.990 Q5EBA0 →
Q8JIF5 0.988 Q8JIF5 →
B0S6U7 0.981 B0S6U7 →
A6H751 0.977 A6H751 →
Q15061 0.975 Q15061 →
O55230 0.974 O55230 →
Q3U3W5 0.972 Q3U3W5 →
Q4QQT0 0.972 Q4QQT0 →
Q68G58 0.972 Q68G58 →
Q96MI9 0.971 Q96MI9 →
E9Q349 0.970 E9Q349 →
B0S8I0 0.970 B0S8I0 →
Q6KAU8 0.970 Q6KAU8 →
Q4KMK0 0.970 Q4KMK0 →
TBRG4 FAST kinase domain-containing protein 4 0.970 landscape →
P48760 0.970 P48760 →
Q149M9 0.970 Q149M9 →
Q3B7U4 0.970 Q3B7U4 →
MAP4K2 Mitogen-activated protein kinase kinase kinase kinase 2 0.970 landscape →
Q99MQ3 0.970 Q99MQ3 →
Q8C6B2 0.969 Q8C6B2 →
Q1JQC5 0.969 Q1JQC5 →
A7E3N7 0.969 A7E3N7 →
Q6DC53 0.969 Q6DC53 →
Q0P5H9 0.969 Q0P5H9 →
Q5R655 0.968 Q5R655 →
Q9R144 0.968 Q9R144 →