Sugi Predict

Sugi Predict / Targets / EXOSC10

EXOSC10

Exosome complex component 10 · Q01780 · EXOSC10 on Sugi Atlas →

0 patent compounds predicted against EXOSC10, 0 high-confidence (nearest known ligand ≥ 0.5)

Top predicted compounds (top 20 by supporting neighbours, then confidence)

CompoundConfidenceSupporting neighbours

Clinical trials — most relevant to EXOSC10 by text similarity (a relevance ranking, not an exhaustive list)

TrialPhaseStatus
Enfortumab Vedotin and Pembrolizumab With Cystectomy and/or Ureterectomy for Locally Advanced or Metastatic Bladder and Upper Urothelial Tract Cancer, CAST-AI Trial PHASE4RECRUITING
The Effect of Stem Cells and Stem Cell Exosomes on Visual Functions in Patients With Retinitis Pigmentosa PHASE2/PHASE3UNKNOWN
Effect of PAE Hydrogel Loaded With tRF-ASO-Exo on Patients With Diabetic Ocular Surface Diseases PHASE2NOT_YET_RECRUITING
A Phase II Randomized, Double-blind, Placebo-controlled Study to Evaluate the Safety and Efficacy of Exosomes Overexpressing CD24 to Prevent Clinical Deterioration in Patients With Moderate or Severe COVID-19 Infection PHASE2UNKNOWN
Intra-discal Injection of Platelet-rich Plasma (PRP) Enriched With Exosomes in Chronic Low Back Pain PHASE1COMPLETED
A Proof of Concept Study to Evaluate Exosomes From Human Mesenchymal Stem Cells in Women With Premature Ovarian Insufficiency (POI) PHASE1SUSPENDED
A Clinical Study on Safety and Effectiveness of Mesenchymal Stem Cell Exosomes for the Treatment of COVID-19. EARLY_PHASE1UNKNOWN
Effect of Plasma Derived Exosomes on Cutaneous Wound Healing EARLY_PHASE1UNKNOWN
The Study of Safety and Preliminary Efficacy of ALT001 in Patients With MultIple System Atrophy-Cerebellar Type EARLY_PHASE1NOT_YET_RECRUITING
Cell Free Circulating Nucleic Acids as New Tumor Diagnostics From Human Plasma Samples. nanUNKNOWN
A Study That Collects Participant Data and Biospecimens to Analyze Pathogenic Exosomes That Mediate Increased Vascular Dementia Risk in Individuals With Herpes Zoster. nanRECRUITING
B3 for NMD: Bench to Bedside and Back nanENROLLING_BY_INVITATION
Role of Exosomes Derived From Epicardial Fat in Atrial Fibrillation nanUNKNOWN
Improving the Early Detection of Lung Cancer by Combining Exosomal Analysis of Hypoxia With Standard of Care Imaging nanUNKNOWN
Identification of New Diagnostic Protein Markers for Colorectal Cancer nanCOMPLETED
A Randomized Trial of Intratympanic Drug Delivery: Evaluating the Efficacy and Safety of Dexamethasone-Loaded Exosomes Versus Standard Therapy in Acute Sensorineural Hearing Loss. nanRECRUITING
When the Kidney Reacts to Nutritional Changes nanCOMPLETED
Exosome-based Liquid Biopsies for Upper Gastrointestinal Cancers Diagnosis nanUNKNOWN
Micro RNAs to Predict Response to Androgen Deprivation Therapy nanCOMPLETED
LINC00511/miR-185-3p Axis and miR-301a-3p Markers for Breast Cancer Diagnosis nanCOMPLETED
Improving Sleep, Sleep-related Outcomes, and Biomarkers in Veterans nanACTIVE_NOT_RECRUITING
Micro RNA Levels in NAFLD nanUNKNOWN
Exosomal microRNAs as a Biomarker in Panic Disorder and in Response to CBT nanUNKNOWN
Exosomes Proteomic for Sjogren's Syndrome and Dry Eye Syndrome nanRECRUITING
A Study of Circulating Exosome Proteomics In Gallbladder Carcinoma Patients nanUNKNOWN
Investigating the Role of Biomarkers in Predicting Outcome for COVID 19 nanUNKNOWN
Integrated Cf-miRNA and Exosomal miRNA Signature for Early Detection of Esophageal Squamous Cell Carcinoma nanRECRUITING
Identification of New Non-invasive, Predictive, and Diagnostic Biomarkers for Colorectal Cancer nanRECRUITING
Upper Body Subcutaneous Exosome Release in Response to a Meal in Obesity nanNOT_YET_RECRUITING
Identification of microRNAs Involved in Cerebral Collateral Regulation nanSUSPENDED

Related proteins — ESM-2 sequence neighbours (a EXOSC10 binder may also engage these)

ProteinNameSimilarity
D4A1X2 — 1.000 D4A1X2 →
P56960 — 1.000 P56960 →
Q6NU40 — 0.986 Q6NU40 →
E1C760 — 0.984 E1C760 →
Q9VFF3 — 0.983 Q9VFF3 →
Q28E45 — 0.983 Q28E45 →
Q9JHD2 — 0.982 Q9JHD2 →
KAT2B Histone acetyltransferase KAT2B 0.982 landscape →
A9LLI8 — 0.982 A9LLI8 →
SMARCC2 SWI/SNF complex subunit SMARCC2 0.982 landscape →
KAT2A Histone acetyltransferase KAT2A 0.982 landscape →
Q80U87 — 0.981 Q80U87 →
Q5BJT6 — 0.981 Q5BJT6 →
Q1LUC3 — 0.981 Q1LUC3 →
F7AEX0 — 0.981 F7AEX0 →
Q2YDM7 — 0.981 Q2YDM7 →
F6QZ15 — 0.981 F6QZ15 →
Q9ESV0 — 0.981 Q9ESV0 →
Q5EAW4 — 0.981 Q5EAW4 →
Q13206 — 0.980 Q13206 →
E9PUQ8 — 0.980 E9PUQ8 →
Q8CH02 — 0.980 Q8CH02 →
Q99LH1 — 0.980 Q99LH1 →
Q0VBD2 — 0.979 Q0VBD2 →
Q68FU8 — 0.979 Q68FU8 →
Q13569 — 0.979 Q13569 →
Q8K2L8 — 0.979 Q8K2L8 →
O13046 — 0.979 O13046 →
Q4TVV3 — 0.979 Q4TVV3 →
Q69ZX6 — 0.978 Q69ZX6 →