SCHEMBL419423

SCHEMBL419423

CCC(C)(C)C(=O)C(=O)N1CCCC[C@H]1C(=O)O[C@H](CCc1ccc(OC)c(OC)c1)c1cccc(OCC(=O)NCCCCC=O)c1

nearest known ligand 0.79

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
FKBP1A P62942 19/20 0.79
FKBP5 Q13451 8/20 0.79
FKBP4 Q02790 7/20 0.79

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL419424 1.00 FKBP1A (0.79) FKBP1AFKBP5FKBP4
SCHEMBL13240345 0.95 FKBP1A (0.85) FKBP1AFKBP5FKBP4
SCHEMBL26026938 0.95 FKBP1A (0.85) FKBP1AFKBP5FKBP4
SCHEMBL29377078 0.95 FKBP1A (0.85) FKBP1AFKBP5FKBP4
SCHEMBL10027139 0.94 FKBP1A (0.79) FKBP1AFKBP5FKBP4
SCHEMBL10027163 0.93 FKBP1A (0.78) FKBP1AFKBP5FKBP4
SCHEMBL15294276 0.93 FKBP1A (0.80) FKBP1AFKBP5FKBP4
SCHEMBL611145 0.93 FKBP1A (0.80) FKBP1AFKBP5FKBP4
SCHEMBL10027140 0.92 FKBP1A (0.78) FKBP1AFKBP5FKBP4
SCHEMBL10061030 0.92 FKBP1A (0.78) FKBP1AFKBP5FKBP4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20120022040-A1 ANTIMICROBIALS AMPLYX PHARMACEUTICALS, INC. 2012-01-26 US disclosed
US-20120022040-A1 ANTIMICROBIALS AMPLYX PHARMACEUTICALS, INC. 2012-01-26 US disclosed
US-20120022040-A1 ANTIMICROBIALS AMPLYX PHARMACEUTICALS, INC. 2012-01-26 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120022040-A1 ANTIMICROBIALS PAM, MPO, OXA1L FKBP1A 4606/4885FKBP5 4666/4885FKBP4 4624/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.