Sugi Predict

Sugi Predict / Targets / FKBP3

FKBP3

Peptidyl-prolyl cis-trans isomerase FKBP3 · Q00688 · FKBP3 on Sugi Atlas →

437 patent compounds predicted against FKBP3, 401 high-confidence (nearest known ligand ≥ 0.5)

Top predicted compounds (top 20 by supporting neighbours, then confidence)

CompoundConfidenceSupporting neighbours
SCHEMBL16937386 SCHEMBL16937386 1.00 1/20
SCHEMBL16949300 SCHEMBL16949300 1.00 1/20
SCHEMBL18354674 SCHEMBL18354674 1.00 1/20
SCHEMBL16937406 SCHEMBL16937406 0.85 1/20
SCHEMBL16948804 SCHEMBL16948804 0.85 1/20
SCHEMBL18354498 SCHEMBL18354498 0.85 1/20
SCHEMBL16937368 SCHEMBL16937368 0.83 1/20
SCHEMBL18354017 SCHEMBL18354017 0.83 1/20
SCHEMBL18359763 SCHEMBL18359763 0.83 1/20
SCHEMBL19594696 SCHEMBL19594696 0.83 1/20
SCHEMBL16927005 SCHEMBL16927005 0.80 1/20
SCHEMBL16937330 SCHEMBL16937330 0.80 1/20
SCHEMBL16937341 SCHEMBL16937341 0.80 1/20
SCHEMBL16938952 SCHEMBL16938952 0.80 1/20
SCHEMBL16948808 SCHEMBL16948808 0.80 1/20
SCHEMBL16949299 SCHEMBL16949299 0.80 1/20
SCHEMBL18354147 SCHEMBL18354147 0.80 1/20
SCHEMBL18354620 SCHEMBL18354620 0.80 1/20
SCHEMBL16937382 SCHEMBL16937382 0.79 1/20
SCHEMBL16948810 SCHEMBL16948810 0.79 1/20

Clinical trials — most relevant to FKBP3 by text similarity (a relevance ranking, not an exhaustive list)

TrialPhaseStatus
Topical Metformin Emulgel VS Salicylic Acid Peeling in Treatment of Acne Vulgaris PHASE4UNKNOWN
OPTImization of the Dose of tacroliMUS by Bayesian Prediction PHASE4COMPLETED
Comparative and Efficacy Study of ACTHar Gel Alone or in Combination With Tacrolimus in Fibrillary Glomerulopathy PHASE4WITHDRAWN
A Study to Evaluate the Efficacy and Safety of Three Fixed Doses of Extended-release Paliperidone in Subjects With Bipolar I Disorder PHASE3COMPLETED
Monoamine Transporters Genotypes: Risk of PTSD and Related Comorbidities PHASE3COMPLETED
Rapamycin for Immunosuppression and B Cell Modulation Post Stem Cell Transplant for Acute Lymphoblastic Leukemia (ALL) PHASE2COMPLETED
Temsirolimus With or Without Megestrol Acetate and Tamoxifen Citrate in Treating Patients With Advanced, Persistent, or Recurrent Endometrial Cancer PHASE2COMPLETED
FK506 (Tacrolimus) in Pulmonary Arterial Hypertension PHASE2COMPLETED
Neurosteroids for PTSD in Veterans PHASE2COMPLETED
A Multicenter Study of NAP (AL-108) in Schizophrenia PHASE2COMPLETED
A Phase I Study of IMC-A12 in Combination With Temsirolimus in Pediatric Patients With Recurrent or Refractory Solid Tumors PHASE1WITHDRAWN
Topical Sirolimus in Patients With Basal Cell Nevus Syndrome and in Healthy Participants PHASE1COMPLETED
Multimodal Neuroimaging of Alcohol Cues, Cortisol Response, and Compulsive Motivation EARLY_PHASE1COMPLETED
FKBP5 Methylation and Childhood Emotional Abuse in Complex Posttraumatic Stress Disorder: Investigating the Relationship and Its Predictive Role in Therapy Outcome nanCOMPLETED
Clinical Implications of FKBP5 in Stroke nanUNKNOWN
Torisel in Addition to Standard Chemotherapy With Radiation for Advanced Head and Neck Cancer nanWITHDRAWN
Cortisol, Hippocampus, and Insula in Anorexia Nervosa. nanRECRUITING
Genetic Predictors of Lithium Response in Bipolar Disorder nanCOMPLETED
Quantification of GADD34 Expression in RA nanCOMPLETED
A Study on Psychopathological Progress of Early Schizophrenia-Like Disorder (SOPRES) nanUNKNOWN
Tacrolimus Pharmacokinetic Subpopulations nanRECRUITING
Efficacy of Achieving Early Target Trough Levels of Tacrolimus Using CYP3A5 Guided Dosing Versus Weight-based Dosing in a Multi-ethnic Population of Kidney Transplant Recipients in Singapore nanCOMPLETED
A Study on Risk Mutations of Vulnerability Genes of Schizophrenia nanUNKNOWN
Sensorimotor Gating in Schizophrenia nanCOMPLETED
Expression of Fas Protein in Skin Biopsies of Participants With Scarring Alopecia nanCOMPLETED
Breathing Focused Yoga in Social Anxiety Disorder nanCOMPLETED
The Partners Genetics Collaborative Study of Schizophrenia nanCOMPLETED
Cerebellar Mutism Syndrome Study nanRECRUITING
Evaluation of Interaction Between Immunosuppressive Drugs and Protein-bound Uremic Toxins in Renal Transplant Patients nanWITHDRAWN
Genetic Variants Associated With Adolescent Suicide Attempts nanCOMPLETED

Related proteins — ESM-2 sequence neighbours (a FKBP3 binder may also engage these)

ProteinNameSimilarity
P26884 — 1.000 P26884 →
O46638 — 0.999 O46638 →
Q62446 — 0.997 Q62446 →
Q9FLB3 — 0.986 Q9FLB3 →
Q26486 — 0.985 Q26486 →
Q5RF88 — 0.984 Q5RF88 →
O18216 — 0.984 O18216 →
Q86A72 — 0.984 Q86A72 →
O60125 — 0.984 O60125 →
Q95L05 — 0.983 Q95L05 →
Q8CGC7 — 0.983 Q8CGC7 →
Q0IIK5 — 0.982 Q0IIK5 →
Q54N80 — 0.982 Q54N80 →
Q38935 — 0.982 Q38935 →
Q641Y8 — 0.982 Q641Y8 →
Q54LA1 — 0.982 Q54LA1 →
Q86JM4 — 0.981 Q86JM4 →
Q93ZG9 — 0.981 Q93ZG9 →
Q6VBQ6 — 0.981 Q6VBQ6 →
Q9ZRI7 — 0.981 Q9ZRI7 →
O94480 — 0.981 O94480 →
Q64378 — 0.981 Q64378 →
Q626C1 — 0.981 Q626C1 →
P02615 — 0.981 P02615 →
Q9VDE4 — 0.981 Q9VDE4 →
Q00313 — 0.981 Q00313 →
Q57XN4 — 0.981 Q57XN4 →
B3LWP6 — 0.981 B3LWP6 →
Q9ZP54 — 0.981 Q9ZP54 →
Q5F408 — 0.981 Q5F408 →