GDI2

Rab GDP dissociation inhibitor beta · P50395 · GDI2 on Sugi Atlas →

0 patent compounds predicted against GDI2, 0 high-confidence (nearest known ligand ≥ 0.5)

Top predicted compounds (top 20 by supporting neighbours, then confidence)

CompoundConfidenceSupporting neighbours

Clinical trials — most relevant to GDI2 by text similarity (a relevance ranking, not an exhaustive list)

TrialPhaseStatus
Simvastatin + Cetuximab/Irinotecan in K-ras Mutant Colorectal Cancer (CRC) PHASE2COMPLETED
Pembrolizumab (MK-3475) in MM Patients With Residual Disease PHASE2COMPLETED
Theophylline Treatment for Pseudohypoparathyroidism - Children 2-12 Years Old PHASE2ACTIVE_NOT_RECRUITING
Efficacy, Safety, Tolerability, Pharmacodynamics, and Pharmacokinetics of BIA 28-6156 in GBA-PD PHASE2ACTIVE_NOT_RECRUITING
FAK Inhibitor in Patients With Advanced Solid Tumors PHASE1NOT_YET_RECRUITING
Taxonomy of Neurodegenerative Diseases : Observational Study in Alzheimer's Disease and Parkinson's Disease nanCOMPLETED
Genetic Investigations in Children With Developmental and Epileptic Encephalopathies in Ho Chi Minh City, Vietnam nanUNKNOWN
Study of People With Generalized Arterial Calcification of Infancy (GACI) or Autosomal Recessive Hypophosphatemic Rickets Type 2 (ARHR2) nanCOMPLETED
Study of the Pathophysiological Mechanisms Involved in Bleeding Events nanCOMPLETED
Biomarker Analysis for GBA Associated Parkinson's Disease nanUNKNOWN
Genetic Studies of Lysosomal Storage Disorders nanENROLLING_BY_INVITATION
Sexually Dimorphic Effects of GHRH in Adult Growth Hormone Testing nanCOMPLETED
PD Frontline (Part of RAPSODI GD) Remote Assessment of People With Parkinson's nanRECRUITING
Exploration of Immunity in Gaucher Disease nanCOMPLETED
Gene Analysis of Parkinson's Disease nanCOMPLETED
NGLY1 Natural History nanCOMPLETED
Investigating the Genetic Basis of Pseudoexfoliation Syndrome, Angle-closure Glaucoma and Primary Open-angle Glaucoma nanRECRUITING
Assessing the Polygenic Burden of Rare Disruptive Mutations in Parkinson's Disease nanUNKNOWN
Parkinson's Research: The Organized Genetics Initiative nanCOMPLETED
Natural History Study of GEMIN-5 Related Neurodevelopmental Disorder nanRECRUITING
Non Motor Symptoms in Glucocerebrosidase-related Parkinson's Disease nanENROLLING_BY_INVITATION
Neurogenetics Patient Registry nanRECRUITING
Genetic Characterization of Parkinson's Disease nanCOMPLETED
AV133 Longitudinal Imaging Study in Patients With Early and Prdromal Parkinson's Disease nanRECRUITING
GNAO1 Natural History Study nanUNKNOWN
Exploring the Genetics of Neuropathic Pain nanRECRUITING
A Phase I Trial of AVN944, an IMPDH Inhibitor, in Adults With Advanced Stage Solid Tumors nanWITHDRAWN
A Study Into the Underlying Biochemical Pathways Involved in Parkinson's Disease, Such as Mitochondrial (Cellular Powerhouse) Dysfunction nanCOMPLETED
Investigation of Copy Number Variations and Genetic Variants in POI nanRECRUITING
Characterization of New Candidate Genes in Cases of Human Inherited Thrombocytopenia (CATCH) nanCOMPLETED

Related proteins — ESM-2 sequence neighbours (a GDI2 binder may also engage these)

ProteinNameSimilarity
Q5RCE1 1.000 Q5RCE1 →
O97556 1.000 O97556 →
P50397 1.000 P50397 →
Q6Q7J2 1.000 Q6Q7J2 →
Q61598 1.000 Q61598 →
P50399 1.000 P50399 →
P60028 0.994 P60028 →
P21856 0.992 P21856 →
Q7YQM0 0.990 Q7YQM0 →
P50396 0.990 P50396 →
P50398 0.989 P50398 →
GDI1 Rab GDP dissociation inhibitor alpha 0.988 landscape →
Q8HXX7 0.985 Q8HXX7 →
O97555 0.984 O97555 →
Q07346 0.952 Q07346 →
Q9LXC0 0.951 Q9LXC0 →
GNPDA1 Glucosamine-6-phosphate deaminase 1 0.949 landscape →
Q42521 0.948 Q42521 →
Q9ZPS3 0.946 Q9ZPS3 →
Q5R8T8 0.945 Q5R8T8 →
Q1W376 0.944 Q1W376 →
Q1W374 0.944 Q1W374 →
A0A0U1WZ18 0.944 A0A0U1WZ18 →
Q9VQZ6 0.943 Q9VQZ6 →
Q2KIG0 0.942 Q2KIG0 →
Q42472 0.941 Q42472 →
Q7XPW5 0.941 Q7XPW5 →
P55931 0.941 P55931 →
Q259G4 0.941 Q259G4 →
Q5RDD3 0.940 Q5RDD3 →