PSAT1

Phosphoserine aminotransferase · Q9Y617 · PSAT1 on Sugi Atlas →

1,382 patent compounds predicted against PSAT1, 791 high-confidence (nearest known ligand ≥ 0.5)

Top predicted compounds (top 20 by supporting neighbours, then confidence)

Compound	Confidence	Supporting neighbours
SCHEMBL15446238	1.00	2/20
Aminooxyphenylpropionate (SCHEMBL1401589)	0.80	2/20
Aminooxyphenylpropionate (SCHEMBL1520985)	0.80	2/20
Aminooxyphenylpropionate (SCHEMBL6513696)	0.80	2/20
Aminooxyphenylpropionate (SCHEMBL1357763)	0.77	2/20
SCHEMBL15446367	0.77	2/20
SCHEMBL15446235	0.72	2/20
SCHEMBL15446229	0.71	2/20
SCHEMBL11298237	0.70	2/20
Bromide (SCHEMBL11297122)	0.68	2/20
SCHEMBL15446243	0.68	2/20
SCHEMBL15446294	0.68	2/20
SCHEMBL288435	0.66	2/20
SCHEMBL15446174	0.65	2/20
SCHEMBL15446199	0.65	2/20
Ethylene (SCHEMBL5331457)	0.63	2/20
Hydrochloric Acid (SCHEMBL3695982)	0.63	2/20
Hydrochloric Acid (SCHEMBL6888643)	0.63	2/20
Hydrochloric Acid (SCHEMBL7567510)	0.63	2/20
SCHEMBL1764568	0.62	2/20

Clinical trials — most relevant to PSAT1 by text similarity (a relevance ranking, not an exhaustive list)

Trial	Phase	Status
Glutamate for Metabolic Intervention in Coronary Surgery	PHASE3	COMPLETED
68Ga-P16-093 and 68Ga-PSMA-617 PET/CT Imaging in the Same Group of Prostate Cancer Patients	PHASE2/PHASE3	UNKNOWN
Acetylcarnitine and Insulin Sensitivity	PHASE2	COMPLETED
Overcoming Primary Resistance to Immunotherapy in Metastatic Melanoma	PHASE2	COMPLETED
Ataxia-telangiectasia: Treating Mitochondrial Dysfunction With a Novel Form of Anaplerosis	PHASE2	COMPLETED
Lu-PSMA and Stereotactic Radiotherapy Versus Radiotherapy Alone for Prostate Cancer (LUST)	PHASE2	RECRUITING
Efficacy and Safety of the Treatment of Pyruvate Dehydrogenase Deficiency Patients With Glycerol Phenylbutyrate (RAVICTI)	PHASE2	RECRUITING
A Study of Bezafibrate in Mitochondrial Myopathy	PHASE2	COMPLETED
Natural History and Advanced Genetic Study of Pyruvate Dehydrogenase Complex Deficiencies	nan	RECRUITING
Correlation Between iXip and Final Pathology Specimen From Radical Prostatectomy: a Multicenter Prospective Trial	nan	UNKNOWN
Abnormalities in the Effects of Insulin and Exercise on Glucose- and Lipid Metabolism in Obesity and Type 2 Diabetes	nan	COMPLETED
Markers of Liver Apoptosis After Anesthesia With Sevoflurane or Propofol	nan	COMPLETED
Estimating Prevalence of Inherited Disorders of Sulfur Amino Acids Metabolism in Patients With Psychotic Disorders.	nan	UNKNOWN
Natural History Study of Pyruvate Dehydrogenase Deficiency	nan	UNKNOWN
Tolerability and Efficacy of L-Serine in Patients With GRIN-related Encephalopathy	nan	UNKNOWN
Thermogenic Silencer Regulatory Factors in Humans	nan	ACTIVE_NOT_RECRUITING
68Ga-P16-093 and 68Ga-PSMA-11 PET/CT Imaging in the Same Group of Primary Prostate Cancer Patients	nan	RECRUITING
Molecular Phenotype Changes and Personalized Treatment for CRPC	nan	UNKNOWN
Sulphate Accumulation in Prostate	nan	COMPLETED
Metabolomic Analysis of Body Fluid of Medulloblastoma in Children	nan	UNKNOWN
13C Pyruvate DNP MR Spectroscopy for Lymphoma Treatment Response Assessment	nan	UNKNOWN
Natural History Study of FDXR Mutation-related Mitochondriopathy	nan	COMPLETED
Dietary Ketosis: Fatty Acids Activate AMPK Energy Circuits Modulating Global Methylation	nan	COMPLETED
Genetic and Metabolic Disease in Children	nan	RECRUITING
Using Next-generation Sequencing in the Diagnosis of Epilepsy and/or Intellectual Disability in a Pediatric Cohorte	nan	COMPLETED
EndoNAFLD: Relationship Between Fatty Liver Disease and Cardiovascular Diseases	nan	COMPLETED
Identification of a New Blood Biomarker for the Diagnosis and Prognosis of Liposarcomas	nan	RECRUITING
The PROFILE Study: Germline Genetic Profiling: Correlation With Targeted Prostate Cancer Screening and Treatment	nan	RECRUITING
Impact Of Choline in Patients With NAFLD	nan	UNKNOWN
Predicting Prostate Biopsy Results With Biomarkers and mpMRI.	nan	COMPLETED

Related proteins — ESM-2 sequence neighbours (a PSAT1 binder may also engage these)

Protein	Name	Similarity
P10658	—	1.000	P10658 →
Q99K85	—	0.999	Q99K85 →
P91856	—	0.995	P91856 →
A9KCT6	—	0.991	A9KCT6 →
B6J1E0	—	0.991	B6J1E0 →
B6J893	—	0.990	B6J893 →
Q83E12	—	0.989	Q83E12 →
A9NC17	—	0.989	A9NC17 →
B8FLC3	—	0.988	B8FLC3 →
B5FCJ8	—	0.988	B5FCJ8 →
B6YQL2	—	0.988	B6YQL2 →
P80862	—	0.988	P80862 →
Q5E6F2	—	0.988	Q5E6F2 →
B1KF45	—	0.988	B1KF45 →
A5CWI0	—	0.987	A5CWI0 →
A1S6D1	—	0.987	A1S6D1 →
Q8RLW0	—	0.987	Q8RLW0 →
A7SCH8	—	0.987	A7SCH8 →
A0LK14	—	0.987	A0LK14 →
A1AWS0	—	0.987	A1AWS0 →
Q9KDM4	—	0.986	Q9KDM4 →
A8FVN8	—	0.986	A8FVN8 →
Q5WWT0	—	0.986	Q5WWT0 →
Q71VT6	—	0.986	Q71VT6 →
Q9VAN0	—	0.986	Q9VAN0 →
B4ET24	—	0.986	B4ET24 →
Q96255	—	0.986	Q96255 →
A5IBR0	—	0.985	A5IBR0 →
A6T1G7	—	0.985	A6T1G7 →
A4VU42	—	0.985	A4VU42 →