GPR180 — patent landscape

Top predicted compounds (top 20 by supporting neighbours, then confidence)

	Compound	Confidence	Supporting neighbours

Clinical trials — most relevant to GPR180 by text similarity (a relevance ranking, not an exhaustive list)

Trial	Phase	Status
Investigating the Potential Role of Aerosolized Retinoic Acid, a Potent Vitamin A Metabolite for Treating COVID-19 Anosmia and Retinoic Acid Insufficiency .A Novel Approach for Regaining Sense of Smell.	PHASE4	UNKNOWN
A Series of Pilot Studies to Evaluate the haemoDynamic and mEtabolic Effects oF apelIn aNd rElaxin	PHASE2	UNKNOWN
Discovery and Validation of Genetic Variants Affecting Microglial Activation in Alzheimer's Disease	PHASE2	ACTIVE_NOT_RECRUITING
Sweet Taste Receptors and the Secretion of Glucagon-like Peptide-1 and Peptide YY	PHASE1	COMPLETED
Role of the Gut Sweet Taste Receptor in the Secretion of Satiation Peptides	PHASE1	COMPLETED
Role of TLR4 in Environmental Asthma	PHASE1	COMPLETED
Dose-response Effect of Pine Nut Oil as a Dual FFA1 and FFA4 Agonist on Glucose Tolerance in Healthy Humans.	nan	COMPLETED
FFAR Agonist on Incretins, Insulin, Lipids and Inflammation	nan	COMPLETED
Neutrophil FFA2/GPR43 Receptor Expression in Patients With the Diagnosis of Sepsis	nan	WITHDRAWN
EPICO: (Study for the Pro-resolution of Chronic Inflammation in Obesity. Original Acronym From Spanish)	nan	UNKNOWN
Clinical Application of PET Imaging Targeting GPA33 in Malignant Tumors	nan	NOT_YET_RECRUITING
Effect of Dietary Oils as G-protein-coupled Receptor Agonists on Glucose Tolerance	nan	UNKNOWN
The Application of 68Ga-Pentixafor Alongside 68Ga-FAPI-04 PET/MR for Assessing Primary Aldosteronism.	nan	NOT_YET_RECRUITING
ZeroTolerance Mucositis: Managing Oral and Alimentary Mucositis With High Potency Sucralfate - ProThelial	nan	UNKNOWN
GABRA2 and the Pharmacokinetics of Risk for Alcoholism (GPRA)	nan	COMPLETED
Oat Bran and Plasma Lipid and Fecal Bacteria in Coronary Artery Disease Patients	nan	COMPLETED
Fat-induced Release of GLP-1 in Humans	nan	COMPLETED
Expression of G-protein Coupled Receptor 120 Receptor in Adipose Tissue of German Diabetes Center Cohort Subjects	nan	COMPLETED
Assessment of CXCL5 Level in SLE Patients and Its Correlation with Disease Activity	nan	NOT_YET_RECRUITING
Colonic Propionate, Appetite, and Weight Loss	nan	COMPLETED
-Oleoyl Glycerol is a GPR119 Agonist and Signals GLP-1 Release in Humans.	nan	COMPLETED
for Adipose Tissue DIabetes VAriants (fATDIVA)	nan	COMPLETED
Gastroparesis Registry 3	nan	COMPLETED
Novel Gentic Variations Contributing to Asthma Susceptability in Saudi Arabia	nan	COMPLETED
The Role of Stromal Cell-Derived Factor-1 (SDF-1)/CXC Chemokine Receptor 4 (CXCR4) in Metastasis of Laryngeal and Hypopharyngeal Squamous Cell Carcinoma	nan	UNKNOWN
Quality of Life, Fatigue and Cognitive, Affective and Emotional Dysfunction in Patients With Cushing's Syndrome	nan	ACTIVE_NOT_RECRUITING
Acute Asthma Responsiveness and B2 Adrenergic Receptors Polymorphisms	nan	COMPLETED
CD36 and Human Fat Taste Perception	nan	COMPLETED
Fatty Acid Metabolism and Insulin Sensitivity: the Role of Endurance Exercise	nan	COMPLETED
GPR109A and Parkinson's Disease: Role of Niacin in Outcome Measures	nan	COMPLETED

Related proteins — ESM-2 sequence neighbours (a GPR180 binder may also engage these)

Protein	Name	Similarity
Q8BPS4	—	1.000	Q8BPS4 →
Q5FWM8	—	0.982	Q5FWM8 →
Q5VW38	—	0.980	Q5VW38 →
Q640M6	—	0.980	Q640M6 →
D3ZWZ9	—	0.977	D3ZWZ9 →
Q80SX5	—	0.977	Q80SX5 →
Q8WTR4	—	0.977	Q8WTR4 →
Q8NBN3	—	0.977	Q8NBN3 →
Q96QZ0	—	0.976	Q96QZ0 →
Q8BUV8	—	0.976	Q8BUV8 →
Q8BXT9	—	0.976	Q8BXT9 →
Q9BRL7	—	0.976	Q9BRL7 →
Q91WD0	—	0.976	Q91WD0 →
Q148L1	—	0.976	Q148L1 →
Q8BXN9	—	0.976	Q8BXN9 →
Q9ESN3	—	0.975	Q9ESN3 →
Q8BKU8	—	0.975	Q8BKU8 →
P0CI65	—	0.975	P0CI65 →
B4N5D3	—	0.974	B4N5D3 →
B4J2W3	—	0.974	B4J2W3 →
B4GZN1	—	0.974	B4GZN1 →
Q6DF19	—	0.974	Q6DF19 →
Q7RTS6	—	0.974	Q7RTS6 →
Q6PP77	—	0.974	Q6PP77 →
Q7TNH6	—	0.974	Q7TNH6 →
Q9NPR9	—	0.973	Q9NPR9 →
Q2LZ37	—	0.973	Q2LZ37 →
Q8CEG0	—	0.973	Q8CEG0 →
B4LC58	—	0.973	B4LC58 →
B4HEB1	—	0.973	B4HEB1 →