Sugi Predict

Sugi Predict / Targets / HEATR6

HEATR6

HEAT repeat-containing protein 6 · Q6AI08 · HEATR6 on Sugi Atlas →

0 patent compounds predicted against HEATR6, 0 high-confidence (nearest known ligand ≥ 0.5)

Top predicted compounds (top 20 by supporting neighbours, then confidence)

CompoundConfidenceSupporting neighbours

Clinical trials — most relevant to HEATR6 by text similarity (a relevance ranking, not an exhaustive list)

TrialPhaseStatus
Effects of Liraglutide on ER Stress in Obese Patients With Type 2 Diabetes PHASE4UNKNOWN
Phase 1/ Phase 2 Study to Assess Safety and Efficacy of Orally Administered JBI-802 in Subjects With Myeloproliferative Neoplasms (MPN) and Myelodysplastic/Myeloproliferative Neoplasms (MDS/MPN) With Thrombocytosis PHASE1/PHASE2RECRUITING
A Phase 2 Study to Investigate the Clinical Activity of IPI-504 in Patients With Hormone-resistant Prostate Cancer PHASE2COMPLETED
Heat Therapy, Functional Capacity, and Vascular Health in Older Adults PHASE1/PHASE2COMPLETED
Validity Study of Glutamine to Improve Cardiac Function in Cardiac Surgery PHASE2COMPLETED
Creatine Therapy for Huntington's Disease PHASE1/PHASE2COMPLETED
Study of Oral CNF2024 (BIIB021) in Advanced Solid Tumors PHASE1COMPLETED
Safety and Pharmacology of SNX-5422 Plus Carboplatin and Paclitaxel in Subjects With Solid Tumors PHASE1COMPLETED
HS-201, an HSP90 Inhibitor-linked Verteporfin for Detection of Solid Malignancies PHASE1WITHDRAWN
PBA Use for Treatment of ATF6-/- Patients EARLY_PHASE1SUSPENDED
Perfusion-Induced Hyperthermia for Metastatic Carcinoma nanCOMPLETED
Exercise on Expression of Heat Shock Protein 70 in Arterial Risk nanCOMPLETED
LncRNA Nicotinamide Nucleotide Transhydrogenase-Antisense RNA1 NNT-AS1 in CRC nanCOMPLETED
Role of Sorcin and Annexin A3 in Breast Cancer Patients nanUNKNOWN
Autophagy in Systemic Lupus Erythematosus nanUNKNOWN
Cardioprotective Benefit of Passive Heat Therapy in Higher-Level Spinal Cord Injury: Safety and Proof of Concept nanUNKNOWN
Chronic Heat Therapy for Improving Vascular Health nanCOMPLETED
Acute Passive Heating in Healthy Older Adults nanCOMPLETED
Hereditary Spastic Paraplegia Genomic Sequencing Initiative (HSPseq) nanRECRUITING
Whole Genome Scan of Extended Families With Familial Vocal Cord Paralysis nanCOMPLETED
Registry and Natural History Study for Early Onset Hereditary Spastic Paraplegia nanRECRUITING
Possible Diagnostic Protein Markers in Schistosoma Related Bladder Diseases. nanNOT_YET_RECRUITING
Characterizing a 5P-Linked BHR Susceptibility Locus nanCOMPLETED
Muscle Wasting in Cancer (MWIC) nanCOMPLETED
Establishment of Human Cellular Disease Models for Wilson Disease nanCOMPLETED
Autophagy Bladder Cancer nanUNKNOWN
Genetic-specific Effects of Fructose on Liver Lipogenesis nanCOMPLETED
Feasibility of Improving Glycemia With Heat Therapy to Prevent AD nanENROLLING_BY_INVITATION
Genetic Characterization of Parkinson's Disease nanCOMPLETED
Changes in Skin Innervation of Neurologically Asymptomatic Type 2 Diabetic Patients: the Correlation With the Diabetic Parameters and Neurotrophins. nanUNKNOWN

Related proteins — ESM-2 sequence neighbours (a HEATR6 binder may also engage these)

ProteinNameSimilarity
Q6P1G0 — 1.000 Q6P1G0 →
Q5R5R2 — 1.000 Q5R5R2 →
A1EC95 — 1.000 A1EC95 →
A9JRI0 — 0.999 A9JRI0 →
Q7ZY56 — 0.997 Q7ZY56 →
Q640K1 — 0.994 Q640K1 →
GCN1 Stalled ribosome sensor GCN1 0.990 landscape →
WDR91 WD repeat-containing protein 91 0.990 landscape →
Q5JWR5 — 0.990 Q5JWR5 →
Q7Z3E5 — 0.990 Q7Z3E5 →
Q8BQM4 — 0.990 Q8BQM4 →
Q5TH69 — 0.990 Q5TH69 →
NCAPD3 Condensin-2 complex subunit D3 0.989 landscape →
F4IP13 — 0.989 F4IP13 →
Q5XG71 — 0.989 Q5XG71 →
Q08CY4 — 0.989 Q08CY4 →
Q6ZQK0 — 0.989 Q6ZQK0 →
E7FGT5 — 0.989 E7FGT5 →
Q9Y3R5 — 0.989 Q9Y3R5 →
Q3UHQ6 — 0.989 Q3UHQ6 →
Q9LYZ7 — 0.989 Q9LYZ7 →
E9PVA8 — 0.989 E9PVA8 →
Q7TMQ7 — 0.989 Q7TMQ7 →
Q8BJW5 — 0.989 Q8BJW5 →
Q7Z4Q2 — 0.988 Q7Z4Q2 →
E1C231 — 0.988 E1C231 →
Q6GPP1 — 0.988 Q6GPP1 →
Q2HJE1 — 0.988 Q2HJE1 →
Q6TEN6 — 0.988 Q6TEN6 →
F6WXT2 — 0.988 F6WXT2 →