HMGB2

High mobility group protein B2 · P26583 · HMGB2 on Sugi Atlas →

0 patent compounds predicted against HMGB2, 0 high-confidence (nearest known ligand ≥ 0.5)

Top predicted compounds (top 20 by supporting neighbours, then confidence)

CompoundConfidenceSupporting neighbours

Clinical trials — most relevant to HMGB2 by text similarity (a relevance ranking, not an exhaustive list)

TrialPhaseStatus
Clinical Evaluation of the Effect of Metformin in Sepsis PHASE3UNKNOWN
The Use of Inhaled Corticosteroids in the Treatment of Asthma is Children in the Emergency Room PHASE2/PHASE3COMPLETED
Cocoa Flavanols for Modulating Immune Response and Accelerating Recovery PHASE1/PHASE2COMPLETED
Statin Intervention for Severe Early-Onset Placental Insufficiency. (STATIN-PRE Trial) PHASE2RECRUITING
MIT-001 for Prevention of CCRT-Induced OM in HNSCC Patients PHASE2ACTIVE_NOT_RECRUITING
the Safety and Efficacy of N-acetyl Cysteine in Children With Drug-Resistant Epilepsy PHASE2COMPLETED
Targeting the Tumor Microenvironment in R/M SCCHN PHASE1/PHASE2UNKNOWN
Simvastatin as Inhibitor of Cell Adhesion Mediated Drug Resistance in Patients With Refractory Multiple Myeloma. PHASE2COMPLETED
Phase II Study of Simvastatin Plus Irinotecan, Fluorouracil, and Leucovorin(FOLFIRI) for Metastatic CRC PHASE2COMPLETED
Pravastatin for Prevention of Preeclampsia PHASE1COMPLETED
EVALUATION OF SALIVARY BİOMARKER LEVELS IN SMOKING AND NON-SMOKER INDIVIDUALS WITH DIFFERENT PERIODONTAL DISEASES nanCOMPLETED
Effects of Cardiac Rehabilitation on High Mobility Group Box-1 Levels After Acute Myocardial Infarction nanCOMPLETED
Markers of Tissue Injury and Rhabdomyolysis in Patients With Major Trauma nanCOMPLETED
Post-surgery Systemic Inflammation and Neuro-immune Interactions nanCOMPLETED
The White Blood Cell Reactivity Following Surgical Trauma and Associated Regulatory Mechanisms. nanCOMPLETED
Macrophage Inhibitory Factor and High-Mobility Group-1 Protein in Children Undergoing Cardiopulmonary Bypass nanCOMPLETED
Role of High Mobility Group Box 1 as a Prognostic Biomarker in Patients Undergoing Valvular Heart Surgery nanCOMPLETED
The Investigation on the Expression of High Mobility Group Protein Box-1 (HMGB1) in Peripheral Blood of Vitiligo Patients and Healthy Controls According to Clinical Features, Treatment and Disease Activity nanCOMPLETED
The Neuroprotective Effect of Dexmedetomidine Preserving Brain Functional Connectivity in Elderly Patients nanCOMPLETED
Evaluating the Relationship of Morphine Consumption and Pain-related Molecules in Hepatic Surgical Patients nanCOMPLETED
A Role for RAGE/TXNIP/Inflammasome Axis in Alveolar Macrophage Activation During ARDS (RIAMA): a Proof-of-concept Clinical Study nanCOMPLETED
Pravastatin Therapy in Patients With Active Crohn's Disease: A Pilot Study nanUNKNOWN
Anti-C1s, Anti-HMGB1 and Anti-C1q Autoantibodies in Systemic Lupus Erythematosus (DYSALARM-322) nanRECRUITING
Inflammatory Biomarkers of Pediatric Pulmonary Hypertension nanCOMPLETED
Effect of Atorvastatin (Lipitor) on Gene Expression in People With Vascular Disease nanCOMPLETED
Histochemical Study of Vitiligo in Sohag University Hospital Patients nanUNKNOWN
HMGB1 Release From Hemorrhagic Shock Patients nanCOMPLETED
Predictive Value of E-cadherin, β-catenin and SOX4 in Recurrence and/or Progression of Non-muscle Invasive Urinary Bladder Transitional Cell Carcinoma. A Retrospective Study nanCOMPLETED
Detection of Circulating Biomarkers of Immunogenic Cell Death nanCOMPLETED
APAP Hepatotoxicity After Therapeutic Doses nanUNKNOWN

Related proteins — ESM-2 sequence neighbours (a HMGB2 binder may also engage these)

ProteinNameSimilarity
P17741 1.000 P17741 →
P40673 1.000 P40673 →
P26584 1.000 P26584 →
P30681 1.000 P30681 →
P52925 1.000 P52925 →
O54879 1.000 O54879 →
HMGB1 High mobility group protein B1 0.999 landscape →
HMGB3 High mobility group protein B3 0.999 landscape →
P10103 0.998 P10103 →
B0CM99 0.997 B0CM99 →
P63159 0.997 P63159 →
P12682 0.997 P12682 →
B2RPK0 0.997 B2RPK0 →
P07156 0.996 P07156 →
P40618 0.996 P40618 →
Q08IE6 0.996 Q08IE6 →
Q9YH06 0.995 Q9YH06 →
P63158 0.995 P63158 →
A9RA84 0.995 A9RA84 →
B1MTB0 0.995 B1MTB0 →
Q4R844 0.995 Q4R844 →
Q6YKA4 0.995 Q6YKA4 →
Q32L31 0.992 Q32L31 →
P07746 0.988 P07746 →
Q06943 0.988 Q06943 →
P40644 0.987 P40644 →
P0CO24 0.987 P0CO24 →
P11873 0.987 P11873 →
Q05783 0.986 Q05783 →
P40625 0.985 P40625 →