Sugi Predict

Sugi Predict / Targets / HSDL2

HSDL2

Hydroxysteroid dehydrogenase-like protein 2 · Q6YN16 · HSDL2 on Sugi Atlas →

0 patent compounds predicted against HSDL2, 0 high-confidence (nearest known ligand ≥ 0.5)

Top predicted compounds (top 20 by supporting neighbours, then confidence)

CompoundConfidenceSupporting neighbours

Clinical trials — most relevant to HSDL2 by text similarity (a relevance ranking, not an exhaustive list)

TrialPhaseStatus
Congenital Adrenal Hyperplasia Once Daily Hydrocortisone Treatment PHASE4RECRUITING
The Role of Mineralocorticoid Receptors in Vascular Function PHASE2/PHASE3COMPLETED
Androgen Ablation Therapy With or Without Chemotherapy in Treating Patients With Metastatic Prostate Cancer PHASE3COMPLETED
Neurosteroids for PTSD in Veterans PHASE2COMPLETED
Efavirenz for Patients With Alzheimer's Disease PHASE1COMPLETED
Mutation Analysis of 17βhydroxysteroid Dehydrogenase 3 Deficiency nanUNKNOWN
Effect of Surgical or Conservative Approach in Patients With Adrenal Incidentalomas nanUNKNOWN
Pattern of Gene Expression in Adipose Tissue From Patients With Cushing Syndrome nanCOMPLETED
Biomarkers in the Etiology of Idiopathic Intracranial Hypertension nanUNKNOWN
HSD3B1 Gene Polymorphisms With Outcomes in SARS-CoV-2 Infected Patients nanCOMPLETED
Linear Growth of Children With Congenital Adrenal Hyperplasia nanUNKNOWN
Final Height in Patients With CAH nanUNKNOWN
Androgens and NAFLD Longitudinal Cohort Study nanRECRUITING
Novel Biomarker for Development of T2D nanCOMPLETED
Polycystic Ovary Syndrome in Type 1 Diabetes nanNOT_YET_RECRUITING
IVF Outcome in Polycystic Ovary Syndrome Patients nanUNKNOWN
Biomarkers in Bone Marrow and Blood Samples From Patients With Prostate Cancer Treated With Ketoconazole nanWITHDRAWN
CXCR4 Targeted PET Imaging in the Diagnosis and Identification of Primary Aldosteronism nanUNKNOWN
Gene Polymorphisms Influencing Steroid Synthesis and Action nanWITHDRAWN
Adrenocortical Functions in Women With Nonclassical 21-hydroxylase Deficiency. nanUNKNOWN
Chocolate and Physical Exercise to Reduce Malnutrition in Pre-dementia Aged People nanUNKNOWN
Determining the Long-Term Effects of Prenatal Dexamethasone Treatment in Children With 21-Hydroxylase Deficiency and Their Mothers nanUNKNOWN
Natural History of Apparent Mineralocorticoid Excess Syndrome nanCOMPLETED
Genetic, Dietary and Environmental Influences on Vitamin D Metabolism nanCOMPLETED
Evaluating a Personalised Online Program With Human Support for Women With Depression and Its Impact on Mental Health and Biological Changes nanNOT_YET_RECRUITING
Cortisol Regulation in Polycystic Ovary Syndrome (PCOS) nanCOMPLETED
Study of Adrenal Gland Tumors nanCOMPLETED
Examining Genetic Differences Among People With 21-Hydroxylase Deficiency nanCOMPLETED
Gut Microbiome in Patients With Polycystic Ovary Syndrome nanUNKNOWN
5-Alpha Reductase 2 as a Marker of Resistance to 5ARI Therapy nanRECRUITING

Related proteins — ESM-2 sequence neighbours (a HSDL2 binder may also engage these)

ProteinNameSimilarity
Q5RA68 — 1.000 Q5RA68 →
A4FUZ6 — 1.000 A4FUZ6 →
Q66KC4 — 1.000 Q66KC4 →
Q6P5L8 — 0.996 Q6P5L8 →
Q6PAY8 — 0.996 Q6PAY8 →
Q9NKW1 — 0.990 Q9NKW1 →
Q2TPA8 — 0.989 Q2TPA8 →
P51660 — 0.987 P51660 →
P97852 — 0.986 P97852 →
HSD17B4 Peroxisomal multifunctional enzyme type 2 0.985 landscape →
Q9CQ62 — 0.984 Q9CQ62 →
Q4V8F9 — 0.983 Q4V8F9 →
P46794 — 0.982 P46794 →
Q59987 — 0.981 Q59987 →
P40747 — 0.981 P40747 →
Q10245 — 0.980 Q10245 →
Q9WVK3 — 0.980 Q9WVK3 →
Q01373 — 0.980 Q01373 →
Q8X1T3 — 0.980 Q8X1T3 →
Q02207 — 0.980 Q02207 →
P16638 — 0.980 P16638 →
P00931 — 0.980 P00931 →
Q3T0C2 — 0.980 Q3T0C2 →
O93918 — 0.979 O93918 →
A8NEP3 — 0.979 A8NEP3 →
DECR1 2,4-dienoyl-CoA reductase [(3E)-enoyl-CoA-producing], mitochondrial 0.979 landscape →
F1C7I4 — 0.979 F1C7I4 →
Q22230 — 0.979 Q22230 →
P13228 — 0.978 P13228 →
O94609 — 0.978 O94609 →