Sugi Predict

Sugi Predict / Targets / HSPA4L

HSPA4L

Heat shock 70 kDa protein 4L · O95757 · HSPA4L on Sugi Atlas →

0 patent compounds predicted against HSPA4L, 0 high-confidence (nearest known ligand ≥ 0.5)

Top predicted compounds (top 20 by supporting neighbours, then confidence)

CompoundConfidenceSupporting neighbours

Clinical trials — most relevant to HSPA4L by text similarity (a relevance ranking, not an exhaustive list)

TrialPhaseStatus
Effects of Liraglutide on ER Stress in Obese Patients With Type 2 Diabetes PHASE4UNKNOWN
Gemcitabine, Docetaxel, and Hydroxychloroquine in Treating Participants With Recurrent or Refractory Osteosarcoma PHASE1/PHASE2ACTIVE_NOT_RECRUITING
OGX-427 in Castration Resistant Prostate Cancer Patients PHASE2COMPLETED
Melpida: Recombinant Adeno-associated Virus (serotype 9) Encoding a Codon Optimized Human AP4M1 Transgene (hAP4M1opt) PHASE1/PHASE2RECRUITING
17AAG to Treat Kidney Tumors in Von Hippel-Lindau Disease PHASE2COMPLETED
Study of Oral CNF2024 (BIIB021) in Advanced Solid Tumors PHASE1COMPLETED
HS-201, an HSP90 Inhibitor-linked Verteporfin for Detection of Solid Malignancies PHASE1WITHDRAWN
Phase I Study of IPI-504 and Docetaxel in Patients With Advanced Solid Tumors PHASE1COMPLETED
Safety and Pharmacology Study of SNX-5422 in Subjects With Resistant Lung Adenocarcinoma PHASE1COMPLETED
Effect of Propofol and Sevoflurane Anesthesia on HSP70 Expression in Tumor Cells EARLY_PHASE1ACTIVE_NOT_RECRUITING
PBA Use for Treatment of ATF6-/- Patients EARLY_PHASE1SUSPENDED
Perfusion-Induced Hyperthermia for Metastatic Carcinoma nanCOMPLETED
Hereditary Spastic Paraplegia Genomic Sequencing Initiative (HSPseq) nanRECRUITING
Exercise on Expression of Heat Shock Protein 70 in Arterial Risk nanCOMPLETED
Registry and Natural History Study for Early Onset Hereditary Spastic Paraplegia nanRECRUITING
Acute Passive Heating in Healthy Older Adults nanCOMPLETED
LncRNA Nicotinamide Nucleotide Transhydrogenase-Antisense RNA1 NNT-AS1 in CRC nanCOMPLETED
Trial of Nonsurgical Treatment of Intermittent Claudication Due to Femoro-popliteal Disease nanCOMPLETED
Possible Diagnostic Protein Markers in Schistosoma Related Bladder Diseases. nanNOT_YET_RECRUITING
Cardioprotective Benefit of Passive Heat Therapy in Higher-Level Spinal Cord Injury: Safety and Proof of Concept nanUNKNOWN
BASE HSP110 : A New Therapeutic Target and a New Marker for Prognosis of Type MSI Colorectal Cancer nanUNKNOWN
Role of Sorcin and Annexin A3 in Breast Cancer Patients nanUNKNOWN
Chronic Heat Therapy for Improving Vascular Health nanCOMPLETED
The Role of HSP90 in Peripheral Vascular Lesions of Diabetic Atherosclerosis nanCOMPLETED
Reduced Ventilator-Free Days and Bacterial Colonization of Sub-Glottic Secretions nanWITHDRAWN
Establishment of Human Cellular Disease Models for Wilson Disease nanCOMPLETED
3D-Microscopic Muscle Architecture in Cerebral Palsy nanRECRUITING
Effect of Exercise on the Human Skeletal Muscle Phosphoproteome nanCOMPLETED
Chronic Passive Heating in Healthy Older Adults nanCOMPLETED
Local Heat-Stress as a Mechanism of Hearing Preservation nanWITHDRAWN

Related proteins — ESM-2 sequence neighbours (a HSPA4L binder may also engage these)

ProteinNameSimilarity
P48722 — 1.000 P48722 →
Q5R606 — 0.997 Q5R606 →
Q5RDM4 — 0.995 Q5RDM4 →
Q61316 — 0.994 Q61316 →
Q0IIM3 — 0.994 Q0IIM3 →
HSPH1 Heat shock protein 105 kDa 0.993 landscape →
O88600 — 0.992 O88600 →
Q2TFN9 — 0.992 Q2TFN9 →
Q61699 — 0.991 Q61699 →
Q66HA8 — 0.991 Q66HA8 →
HSPA4 Heat shock 70 kDa protein 4 0.991 landscape →
Q60446 — 0.986 Q60446 →
F4HQD4 — 0.968 F4HQD4 →
Q9S7C0 — 0.967 Q9S7C0 →
Q9QW07 — 0.964 Q9QW07 →
Q5R8R4 — 0.964 Q5R8R4 →
Q7ZY60 — 0.963 Q7ZY60 →
Q4V7N2 — 0.962 Q4V7N2 →
A0FKG7 — 0.961 A0FKG7 →
Q642Q1 — 0.961 Q642Q1 →
Q9Z1F9 — 0.960 Q9Z1F9 →
Q9SV20 — 0.960 Q9SV20 →
Q5RGJ5 — 0.960 Q5RGJ5 →
O55091 — 0.960 O55091 →
Q8BPM2 — 0.960 Q8BPM2 →
UBA2 SUMO-activating enzyme subunit 2 0.960 landscape →
Q64514 — 0.959 Q64514 →
Q15147 — 0.959 Q15147 →
Q7ZWS1 — 0.959 Q7ZWS1 →
Q5ZLV4 — 0.959 Q5ZLV4 →