SCHEMBL22360286

SCHEMBL22360286

CC(=O)NC1C(O)[C@H](O[C@@H]2OC(CO)[C@H](O)C(O)C2O[C@@H]2OC(C)[C@@H](O)C(O)C2O)C(CO)O[C@H]1OCCCCCN

nearest known ligand 0.71

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LGALS3 P17931 3/20 0.71
LGALS8 O00214 2/20 0.71
LGALS4 P56470 2/20 0.71
MAPK1 P28482 1/20 0.56
BMP2 P12643 3/20 0.49
VEGFA P15692 3/20 0.49
IFNG P01579 2/20 0.49
FGF1 P05230 1/20 0.49
FGF2 P09038 1/20 0.49
SFRP1 Q8N474 1/20 0.49
IGF2R P11717 2/20 0.47
CXCL12 P48061 2/20 0.43
SHH Q15465 2/20 0.43
PF4 P02776 1/20 0.43
CCL2 P13500 1/20 0.43
SELP P16109 1/20 0.43
BMP6 P22004 1/20 0.43
CCL11 P51671 1/20 0.43
WNT3A P56704 1/20 0.43
SELPLG Q14242 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15479618 0.92 LGALS8 (0.60) LGALS3LGALS8LGALS4MAPK1BMP2
SCHEMBL15482022 0.92 LGALS8 (0.60) LGALS3LGALS8LGALS4MAPK1BMP2
SCHEMBL19829889 0.92 LGALS8 (0.60) LGALS3LGALS8LGALS4MAPK1BMP2
SCHEMBL18011565 0.92 LGALS8 (0.60) LGALS3LGALS8LGALS4MAPK1BMP2
SCHEMBL13541636 0.92 LGALS8 (0.60) LGALS3LGALS8LGALS4MAPK1BMP2
SCHEMBL29374092 0.92 LGALS8 (0.59) LGALS3LGALS8LGALS4MAPK1BMP2
SCHEMBL21851367 0.91 LGALS8 (0.61) LGALS3LGALS8LGALS4MAPK1BMP2
SCHEMBL17832655 0.89 LGALS8 (0.60) LGALS3LGALS8LGALS4MAPK1BMP2
SCHEMBL19614147 0.89 LGALS8 (0.60) LGALS3LGALS8LGALS4MAPK1BMP2
SCHEMBL17822272 0.89 LGALS8 (0.60) LGALS3LGALS8LGALS4MAPK1BMP2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20200262881-A1 pHLIP-Mediated Carbohydrate Tethering at Cell Surfaces to Induce Immune Response UNIVERSITY OF RHODE ISLAND BOARD OF TRUSTEES 2020-08-20 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20200262881-A1 pHLIP-Mediated Carbohydrate Tethering at Cell Surfaces to Induce Immune Response PHLPP1, CD4, CD14 LGALS3 133/4885LGALS8 100/4885LGALS4 117/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.