Sugi Predict

Sugi Predict / Targets / IPO11

IPO11

Importin-11 · Q9UI26 · IPO11 on Sugi Atlas →

0 patent compounds predicted against IPO11, 0 high-confidence (nearest known ligand ≥ 0.5)

Top predicted compounds (top 20 by supporting neighbours, then confidence)

CompoundConfidenceSupporting neighbours

Clinical trials — most relevant to IPO11 by text similarity (a relevance ranking, not an exhaustive list)

TrialPhaseStatus
Impact of tdrd9 Gene Mutations in the Therapeutic Response to L-carnitine in Oligoasthenozoospermic Men PHASE3ACTIVE_NOT_RECRUITING
Selinexor With ICE Chemotherapy in Secondary Central Nervous System Involving B-cell Non-Hodgkin Lymphoma PHASE1/PHASE2RECRUITING
A Phase Ib/II Clinical Study Evaluating the Safety and Efficacy of Tislelizumab in Combination With Golidocitinib and Selinexor for the Treatment of R/R NKTCL PHASE1/PHASE2RECRUITING
A Phase 2 Trial of SCO-101 in Combination With FOLFIRI for Patients With Metastatic Colorectal Cancer (mCRC) With Acquired Resistance to FOLFIRI PHASE1/PHASE2UNKNOWN
Selinexor for the Treatment of Intermediate and High-Risk Smoldering Multiple Myeloma PHASE2RECRUITING
Selinexor, High-dose Methotrexate, and Rituximab Combined With Radiotherapy for Newly Diagnosed, Transplant-ineligible Patients With Central Nervous System Lymphoma: An Open-label, Single-arm, Multicenter Phase II Study PHASE2RECRUITING
Safety Study of Adjuvant Vaccine to Treat Melanoma Patients PHASE1/PHASE2COMPLETED
A Trial of Selinexor, Ruxolitinib and Methylprednisolone PHASE1RECRUITING
IMP321 Phase 1 Trial in Metastatic Renal Cell Carcinoma (MRCC) PHASE1COMPLETED
Prognostic Value of Protein IMP3 Expression in Cervical Cancer nanCOMPLETED
The Influence of Genetic Variations in ELAPOR1 or ELAPOR2 on Insulin Secretion and Glucose Regulation in Humans nanUNKNOWN
Pulmonary Hypertension--Mechanisms and Family Registry nanCOMPLETED
MEHMO Natural History and Biomarkers nanRECRUITING
Finding Genes With NGS Techniques in Whom Mutations Cause Neurological Diseases nanUNKNOWN
Next-Generation Sequencing-based Germline and Somatic Genetic Testing in Triple-negative Breast Cancer nanUNKNOWN
Whole-genome Sequencing Study in Patients With Diminished Ovarian Reserve nanUNKNOWN
Plasma Triglyceride Lipolysis in Multifactorial Chylomicronemia nanCOMPLETED
Genetic Studies Spermatogenic Failure nanCOMPLETED
Universal Rare Gene Study: A Registry and Natural History Study of Retinal Dystrophies Associated With Rare Disease-Causing Genetic Variants nanRECRUITING
Genetics of Endocrine Tumours - Familial Isolated Pituitary Adenoma - FIPA nanRECRUITING
A Study of Drug Therapies for Salivary Gland Cancers Based on Testing of Genes nanCOMPLETED
Intestinal Microbiota and Visceral Pain in Chronic Intestinal Pseudo-Obstruction Syndrome (CIPO) nanNOT_YET_RECRUITING
Uncovering Genes Behind Cartilage Tumors and Vascular Anomalies Using Genomic Sequencing nanRECRUITING
Genetic Markers and Biomarkers in Patients With Intellectual Disabilities of Genetic Origin nanRECRUITING
Aberrant Splicings Due to Microsatellite Instability in Colorectal Cancer : Physiopathological and Clinical Impact nanUNKNOWN
DNA Single Nucleotide Polymorphisms as Predictors of Toxicity nanUNKNOWN
The Clinical Study of Sex Chromosome Variants nanCOMPLETED
Whole Genome Analysis for the Detection of Key Genes in the Polycystic Ovary Syndrome nanUNKNOWN
Study of Neurodegenerative Diseases Induced Stem Cells in Patients and Healthy Family Controls. nanUNKNOWN
UW Undiagnosed Genetic Diseases Program nanRECRUITING

Related proteins — ESM-2 sequence neighbours (a IPO11 binder may also engage these)

ProteinNameSimilarity
Q8K2V6 — 0.999 Q8K2V6 →
Q7TMY7 — 0.988 Q7TMY7 →
Q8AY73 — 0.987 Q8AY73 →
CSE1L Exportin-2 0.986 landscape →
A5WW24 — 0.986 A5WW24 →
Q91YE6 — 0.985 Q91YE6 →
Q6GMY9 — 0.985 Q6GMY9 →
IPO7 Importin-7 0.985 landscape →
IPO8 Importin-8 0.984 landscape →
Q5R9J2 — 0.984 Q5R9J2 →
IPO9 Importin-9 0.984 landscape →
Q9EPL8 — 0.984 Q9EPL8 →
XPO5 Exportin-5 0.984 landscape →
Q924C1 — 0.984 Q924C1 →
A5D785 — 0.984 A5D785 →
IPO5 Importin-5 0.984 landscape →
Q9ERK4 — 0.983 Q9ERK4 →
Q569Z2 — 0.982 Q569Z2 →
Q8BKC5 — 0.982 Q8BKC5 →
Q9EPK7 — 0.982 Q9EPK7 →
Q704U0 — 0.982 Q704U0 →
Q9PTU3 — 0.981 Q9PTU3 →
Q7SZC2 — 0.981 Q7SZC2 →
Q5ZLT0 — 0.980 Q5ZLT0 →
Q5R9G4 — 0.980 Q5R9G4 →
Q9CRT8 — 0.980 Q9CRT8 →
Q9H2T7 — 0.980 Q9H2T7 →
XPO7 Exportin-7 0.979 landscape →
P14068 — 0.979 P14068 →
Q99NF8 — 0.978 Q99NF8 →