ITGB4

Integrin beta-4 · P16144 · ITGB4 on Sugi Atlas →

0 patent compounds predicted against ITGB4, 0 high-confidence (nearest known ligand ≥ 0.5)

Top predicted compounds (top 20 by supporting neighbours, then confidence)

CompoundConfidenceSupporting neighbours

Clinical trials — most relevant to ITGB4 by text similarity (a relevance ranking, not an exhaustive list)

TrialPhaseStatus
99mTc-3PRGD2 SPECT/CT for Integrin Imaging of Lung Cancer PHASE3COMPLETED
68 Ga-NODAGA-E[c(RGDγK)]2: Positron Emission Tomography Tracer for Imaging of Angiogenesis in Ischemic Heart Disease PHASE2UNKNOWN
Monoclonal Antibody Therapy in Treating Patients With Advanced Colorectal Cancer PHASE1/PHASE2COMPLETED
Abciximab (ReoPro) as a Therapeutic Intervention for Sickle Cell Vaso-Occlusive Pain Crisis PHASE2WITHDRAWN
Cilengitide in Treating Patients With Prostate Cancer PHASE2COMPLETED
A Phase IIa Study of Intravenous Rituximab in Pediatric Participants With Severe Granulomatosis With Polyangiitis (Wegener's) or Microscopic Polyangiitis PHASE2COMPLETED
Vedolizumab (Anti-alpha4beta7) in Subjects With HIV Infection Undergoing Analytical Treatment Interruption PHASE1COMPLETED
Safety/Biomarker Study of CNTO 95 and Avastin in Solid Tumors PHASE1COMPLETED
Study to Evaluate Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of BIIB107 in Healthy Adult Participants PHASE1COMPLETED
A Gene Therapy Trial to Evaluate the Safety and Efficacy of RP-L201 in Subjects With Leukocyte Adhesion Deficiency-I PHASE1WITHDRAWN
68Ga-NOTA-PRGD2 PET/CT in Patients With Lung Injury and Pulmonary Fibrosis EARLY_PHASE1UNKNOWN
68Ga-BNOTA-PRGD2 PET/CT in Patients With Rheumatoid Arthritis EARLY_PHASE1UNKNOWN
68Ga-BNOTA-PRGD2 PET/CT in Diagnosis and Evaluation of Glioma EARLY_PHASE1UNKNOWN
68Ga-BNOTA-PRGD2 PET/CT in Evaluation of Stroke EARLY_PHASE1UNKNOWN
68Ga-BNOTA-PRGD2 PET/CT in Evaluation of Myocardial Infarction EARLY_PHASE1UNKNOWN
68Ga-BNOTA-PRGD2 PET/CT in Healthy Volunteers and Lung Cancer Patients EARLY_PHASE1UNKNOWN
Angiogenesis and Fibrosis in Aortic Stenosis nanCOMPLETED
Anti-αIIbβ3 Immunization in Glanzmann Thrombasthenia: Prevalence and Associated Risk Factors: Thrombasthenia Anti-αIIbβ3 Antibodies Study (TAAS) nanCOMPLETED
The Role of CD4+ T Cell Subsets in the Mechanism of Action of Vedolizumab in Ulcerative Colitis nanUNKNOWN
IMaging Pilot Study of the αvβ6 Integrin Radiotracer [18F]-A20FMDV2 in PAtients With Solid Cancer Types nanCOMPLETED
Angiogenesis and Fibrosis in Myocardial Infarction nanCOMPLETED
Clinical Study of 18F-FAPI-RGD in Ovarian Cancer nanCOMPLETED
ITGA2b and SELP Expression in Cancer Pancreas and Biliary Tract Cancer nanUNKNOWN
Clinical Study of 18F-FAPI-RGD in Breast Tumors nanCOMPLETED
Clinical Pattern of Glanzemnn Thrombathenia in Children Attending Assiut University Children Hospital nanNOT_YET_RECRUITING
68Ga-NODAGA-RGD PET in Patients With an Occluded Coronary Artery nanUNKNOWN
Integrin αvβ6-targeted PET in Malignant Tumors nanRECRUITING
In-vivo Thrombus Imaging With 18F-GP1, a Novel Platelet PET Radiotracer nanCOMPLETED
Eosinophil β1 Integrin Activation as a Biomarker for Eosinophilic Esophagitis nanCOMPLETED
The Role of Platelet Surface α2β1 Integrin Expression as a Risk Factor in Thrombotic and/or Bleeding Complications nanCOMPLETED

Related proteins — ESM-2 sequence neighbours (a ITGB4 binder may also engage these)

ProteinNameSimilarity
A2A863 1.000 A2A863 →
Q64632 1.000 Q64632 →
Q6AYF4 0.992 Q6AYF4 →
ITGB2 Integrin beta-2 0.991 landscape →
Q1RPR6 0.990 Q1RPR6 →
P32592 0.990 P32592 →
Q9Z0T9 0.988 Q9Z0T9 →
P18563 0.988 P18563 →
P11835 0.988 P11835 →
Q6ECI6 0.987 Q6ECI6 →
P26011 0.987 P26011 →
Q8SQB8 0.987 Q8SQB8 →
Q863C4 0.987 Q863C4 →
Q5VI41 0.987 Q5VI41 →
P12607 0.987 P12607 →
ITGB7 Integrin beta-7 0.987 landscape →
Q2VJ42 0.987 Q2VJ42 →
P53714 0.986 P53714 →
ITGB1 Integrin beta-1 0.985 landscape →
Q9DBX3 0.985 Q9DBX3 →
Q27874 0.985 Q27874 →
Q5RCA9 0.985 Q5RCA9 →
ITGB6 Integrin beta-6 0.984 landscape →
ADAM10 Disintegrin and metalloproteinase domain-containing protein 10 0.984 landscape →
Q13753 0.984 Q13753 →
O77633 0.984 O77633 →
P23377 0.984 P23377 →
P11584 0.983 P11584 →
A1X150 0.983 A1X150 →
Q03145 0.983 Q03145 →