Sugi Predict

Sugi Predict / Targets / IWS1

IWS1

Protein IWS1 homolog · Q96ST2 · IWS1 on Sugi Atlas →

0 patent compounds predicted against IWS1, 0 high-confidence (nearest known ligand ≥ 0.5)

Top predicted compounds (top 20 by supporting neighbours, then confidence)

CompoundConfidenceSupporting neighbours

Clinical trials — most relevant to IWS1 by text similarity (a relevance ranking, not an exhaustive list)

TrialPhaseStatus
Cornelia De Lange Syndrome: Assessing Positive Effects of Lithium Treatment PHASE2/PHASE3RECRUITING
WT1 for the Detection of Minimal Residual Disease PHASE2/PHASE3COMPLETED
Efficacy Study of Daily Administration of VPA in Patients Affected by Wolfram Syndrome PHASE2UNKNOWN
Study of the Beach Regimen on Relapsed/Refractory Acute Myeloid Leukemia (R/R AML) PHASE2ACTIVE_NOT_RECRUITING
Gene Therapy for Wiskott-Aldrich Syndrome PHASE1/PHASE2COMPLETED
Safety and Efficacy Study of PRI-724 Plus Gemcitabine in Subjects With Advanced or Metastatic Pancreatic Adenocarcinoma PHASE1COMPLETED
Digoxin for Congenital Erythrocytosis Due to Up-Regulated Hypoxia Sensing PHASE1WITHDRAWN
Eosinophil Induced Remodelling in Asthma nanCOMPLETED
I-Tracking Neurodegeneration in Early Wolfram Syndrome nanCOMPLETED
Aberrant Splicings Due to Microsatellite Instability in Colorectal Cancer : Physiopathological and Clinical Impact nanUNKNOWN
Evaluation of the Effects of KCNQ1 Mutation on Insulin Tolerance and Obsessive Compulsive Features in Long QT Romano-Ward Syndrome Patients. nanUNKNOWN
Characterization of WAGR Syndrome and Other Chromosome 11 Gene Deletions nanCOMPLETED
A Study of Multilocus Methylation Abnormalities in Subjects With Imprinting Disorders nanNOT_YET_RECRUITING
A Retrospective and Prospective Natural History Study of Patients With WHIM Syndrome nanWITHDRAWN
Uncovering the Etiologies of Non-immune Hydrops Fetalis nanENROLLING_BY_INVITATION
Genetic Hallmarks of Patients With Congenital Portosystemic Shunts and Portopulmonary Hypertension nanNOT_YET_RECRUITING
Mechanisms of Inherited Retinal Dystrophies Using Whole Genome Sequencing and in Vitro and in Vivo Models nanCOMPLETED
Genetic Analysis of Fraser Syndrome and Fryns Syndrome nanCOMPLETED
Identification of Genetic Factors Implicated in Orofacial Cleft Using Whole Exome Sequencing nanRECRUITING
Abnormalities in the Effects of Insulin and Exercise on Glucose- and Lipid Metabolism in Obesity and Type 2 Diabetes nanCOMPLETED
Williams Syndrome (WS) and Supravalvar Aortic Stenosis (SVAS) DNA and Tissue Bank nanCOMPLETED
Genetic Physiopathology and Evolution of Type 2 Diabetes nanCOMPLETED
Defining the Brain Phenotype of Children With Williams Syndrome nanRECRUITING
Maternal Genes and Epimutations: Beckwith-Wiedemann Syndrome & Reproductive Risks nanRECRUITING
Study of Tazemetostat in Adults With Follicular Lymphoma Previously Treated With at Least Two Therapies nanWITHDRAWN
An Assistant Model for IRD Care Needs: A Randomized Control Trial nanCOMPLETED
Better Delineation of YY1 Related Phenotype and Epigenetic Signatures. nanUNKNOWN
PHF19 Gene Expression and EZH2 Gene Deletion in Acute Myeloid Leukemia nanUNKNOWN
Podocyts Integrity in Glomerular Diseases nanUNKNOWN
Diagnosis of Prader-Willi Syndrome and Angelman Syndrome nanCOMPLETED

Related proteins — ESM-2 sequence neighbours (a IWS1 binder may also engage these)

ProteinNameSimilarity
Q8C1D8 — 1.000 Q8C1D8 →
Q3SWT4 — 0.998 Q3SWT4 →
Q6DE96 — 0.994 Q6DE96 →
Q505H7 — 0.993 Q505H7 →
LEO1 RNA polymerase-associated protein LEO1 0.988 landscape →
Q5XJE5 — 0.987 Q5XJE5 →
Q641X2 — 0.986 Q641X2 →
Q52KV5 — 0.986 Q52KV5 →
Q94546 — 0.980 Q94546 →
Q5R4D6 — 0.980 Q5R4D6 →
Q6NYV9 — 0.977 Q6NYV9 →
A0A1I8M2I8 — 0.976 A0A1I8M2I8 →
Q8C5N3 — 0.976 Q8C5N3 →
Q568R1 — 0.975 Q568R1 →
PNN Pinin 0.975 landscape →
U2SURP U2 snRNP-associated SURP motif-containing protein 0.974 landscape →
Q9W261 — 0.973 Q9W261 →
Q04870 — 0.972 Q04870 →
Q6NV83 — 0.972 Q6NV83 →
O35691 — 0.972 O35691 →
Q5R5X0 — 0.972 Q5R5X0 →
Q76MT4 — 0.972 Q76MT4 →
Q9SU25 — 0.972 Q9SU25 →
Q61136 — 0.972 Q61136 →
F4ICK8 — 0.972 F4ICK8 →
A0A286Y9D1 — 0.972 A0A286Y9D1 →
CWC22 Pre-mRNA-splicing factor CWC22 homolog 0.972 landscape →
Q28C44 — 0.971 Q28C44 →
Q08C72 — 0.971 Q08C72 →
Q5RKH1 — 0.971 Q5RKH1 →