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KIF20B

Kinesin-like protein KIF20B · Q96Q89 · KIF20B on Sugi Atlas →

146 patent compounds predicted against KIF20B, 77 high-confidence (nearest known ligand ≥ 0.5)

Top predicted compounds (top 20 by supporting neighbours, then confidence)

CompoundConfidenceSupporting neighbours
Physodic Acid Physodic Acid (SCHEMBL10383128) 1.00 2/20
SCHEMBL30883024 SCHEMBL30883024 1.00 2/20
SCHEMBL17975283 SCHEMBL17975283 0.86 2/20
Oxyphysodic Acid Oxyphysodic Acid (SCHEMBL17988183) 0.77 2/20
SCHEMBL17988185 SCHEMBL17988185 0.77 2/20
SCHEMBL18351635 SCHEMBL18351635 0.70 2/20
SCHEMBL17975296 SCHEMBL17975296 0.69 2/20
SCHEMBL17975289 SCHEMBL17975289 0.68 2/20
SCHEMBL15294483 SCHEMBL15294483 0.63 2/20
SCHEMBL30059040 SCHEMBL30059040 0.61 2/20
SCHEMBL15294481 SCHEMBL15294481 0.60 2/20
Lobaric Acid Lobaric Acid (SCHEMBL3910434) 0.59 2/20
Lobaric Acid Lobaric Acid (SCHEMBL29431924) 0.59 2/20
Lobaric Acid Lobaric Acid (SCHEMBL29788372) 0.59 2/20
SCHEMBL17975293 SCHEMBL17975293 0.58 2/20
SCHEMBL30055749 SCHEMBL30055749 0.58 2/20
SCHEMBL14703230 SCHEMBL14703230 0.55 2/20
SCHEMBL17988184 SCHEMBL17988184 0.53 2/20
SCHEMBL15178484 SCHEMBL15178484 0.52 2/20
SCHEMBL17975305 SCHEMBL17975305 0.48 2/20

Clinical trials — most relevant to KIF20B by text similarity (a relevance ranking, not an exhaustive list)

TrialPhaseStatus
Safety Evaluation of Gene Therapy in Leber Hereditary Optic Neuropathy (LHON) Patients PHASE1/PHASE2COMPLETED
A Study to Investigate Safety, Tolerability, Pharmacokinetics and Preliminary Efficacy With GenSci122 in Participants With Advanced Solid Tumors PHASE1RECRUITING
Functional Studies of Novel Genes Mutated in Primary Ciliary Dyskinesia II: Genotype to Phenotype EARLY_PHASE1COMPLETED
Progressive Familial Intrahepatic Cholestasis in Indian Children - Establishing an Indian PFIC Registry nanUNKNOWN
Genetic Study of Patients With Primary Ciliary Dyskinesia nanCOMPLETED
Natural History Study of SLC25A46 Mutation-related Mitochondriopathy nanCOMPLETED
Genetic Studies of Strabismus, Congenital Cranial Dysinnervation Disorders (CCDDs), and Their Associated Anomalies nanRECRUITING
Natural History Evaluation of Charcot Marie Tooth Disease (CMT) Types CMT1B, CMT2A, CMT4A, CMT4C, and Others nanRECRUITING
Delineating the Molecular Spectrum and the Clinical, Imaging and Neuronal Phenotype of Chopra-Amiel-Gordon Syndrome nanRECRUITING
Biomarker Research in Inherited Movement Disorders nanRECRUITING
Mapping Disease Pathways for Biliary Atresia nanRECRUITING
iPSC Neurons From Adult Survivors of Childhood Cancer Who Have Persistent Vincristine-Induced Neuropathy nanCOMPLETED
Better Delineation of CDK13 Related Phenotype and Epigenetic Signature. nanUNKNOWN
Registry and Natural History of Epilepsy-Dyskinesia Syndromes nanRECRUITING
Genetics of Pediatric-Onset Motor Neuron and Neuromuscular Diseases nanCOMPLETED
Classification, Functional Stratification and Biomarkers in Ciliopathy (CILLICORIRCM) nanCOMPLETED
Hong Kong Spinocerebellar Ataxias Registry nanRECRUITING
Assessing the Polygenic Burden of Rare Disruptive Mutations in Parkinson's Disease nanUNKNOWN
Markers and Mechanisms of Macrovascular Disease in IDDM nanCOMPLETED
Pathogenesis of Primary Ciliary Dyskinesia (PCD) Lung Disease nanRECRUITING
A Retrospective Survey-based Multicenter Study to Delineate the Molecular and Phenotypic Spectrum of Epilepsy-dyskinesia Syndromes nanRECRUITING
Characteristics of Episodic Ataxia Syndrome nanCOMPLETED
Muscle Tissue Bank for Muscular Dystrophy nanCOMPLETED
Gait in Rare Diseases nanCOMPLETED
Genetics of Primary Ciliary Dyskinesia nanCOMPLETED
Evaluation and Treatment of Pediatric, Developmental, and Genetic Eye Diseases nanCOMPLETED
PCD New Gene Discovery nanCOMPLETED
Clinical and Molecular Correlations in Spinocerebellar Ataxia Type 10 (SCA10) nanCOMPLETED
Pediatric Evaluation and Registry for Liver Cholestasis in Canada nanRECRUITING
Investigation of the Genetic Causes of Kallmann Syndrome and Reproductive Disorders nanCOMPLETED

Related proteins — ESM-2 sequence neighbours (a KIF20B binder may also engage these)

ProteinNameSimilarity
Q80WE4 — 0.997 Q80WE4 →
P53086 — 0.990 P53086 →
P27895 — 0.990 P27895 →
Q8J1G7 — 0.989 Q8J1G7 →
Q92376 — 0.989 Q92376 →
O60114 — 0.987 O60114 →
F4JZ68 — 0.987 F4JZ68 →
F4I1T9 — 0.987 F4I1T9 →
F4JX00 — 0.987 F4JX00 →
Q02979 — 0.987 Q02979 →
P41412 — 0.986 P41412 →
P06701 — 0.986 P06701 →
P40450 — 0.986 P40450 →
O59751 — 0.986 O59751 →
Q91FG5 — 0.986 Q91FG5 →
P33420 — 0.986 P33420 →
F4JQ51 — 0.986 F4JQ51 →
Q6FXI5 — 0.986 Q6FXI5 →
O13987 — 0.986 O13987 →
B3H6Z8 — 0.986 B3H6Z8 →
Q9Y7X7 — 0.986 Q9Y7X7 →
P0CY09 — 0.986 P0CY09 →
P0CY08 — 0.986 P0CY08 →
Q9C104 — 0.985 Q9C104 →
Q8L7Y8 — 0.985 Q8L7Y8 →
Q59WD5 — 0.985 Q59WD5 →
Q06696 — 0.985 Q06696 →
F4IIS5 — 0.985 F4IIS5 →
G5EDY0 — 0.985 G5EDY0 →
Q6BYU4 — 0.985 Q6BYU4 →