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Sugi Predict / Targets / KLHL20

KLHL20

Kelch-like protein 20 · Q9Y2M5 · KLHL20 on Sugi Atlas →

184 patent compounds predicted against KLHL20, 89 high-confidence (nearest known ligand ≥ 0.5)

Top predicted compounds (top 20 by supporting neighbours, then confidence)

CompoundConfidenceSupporting neighbours
SCHEMBL22342251 SCHEMBL22342251 0.60 1/20
SCHEMBL23818055 SCHEMBL23818055 0.59 1/20
SCHEMBL22342253 SCHEMBL22342253 0.57 1/20
SCHEMBL22342181 SCHEMBL22342181 0.57 1/20
SCHEMBL26428955 SCHEMBL26428955 0.55 1/20
SCHEMBL21663879 SCHEMBL21663879 0.54 1/20
SCHEMBL25455411 SCHEMBL25455411 0.54 1/20
SCHEMBL25455440 SCHEMBL25455440 0.54 1/20
SCHEMBL25455215 SCHEMBL25455215 0.53 1/20
SCHEMBL25455280 SCHEMBL25455280 0.53 1/20
SCHEMBL25455823 SCHEMBL25455823 0.53 1/20
SCHEMBL25457446 SCHEMBL25457446 0.53 1/20
SCHEMBL25457616 SCHEMBL25457616 0.53 1/20
SCHEMBL25455829 SCHEMBL25455829 0.53 1/20
SCHEMBL25457182 SCHEMBL25457182 0.53 1/20
SCHEMBL22342182 SCHEMBL22342182 0.53 1/20
SCHEMBL25455282 SCHEMBL25455282 0.52 1/20
SCHEMBL25455977 SCHEMBL25455977 0.52 1/20
SCHEMBL21664108 SCHEMBL21664108 0.52 1/20
SCHEMBL25455198 SCHEMBL25455198 0.51 1/20

Clinical trials — most relevant to KLHL20 by text similarity (a relevance ranking, not an exhaustive list)

TrialPhaseStatus
Applying Proton Pump Inhibitor to Prevent and Treat Acute Fluctuating Hearing Loss in Patients With SLC26A4 Mutation PHASE2/PHASE3UNKNOWN
Histocompatibility Leukocyte Antigen (HLA)-A*2402 Restricted Peptide Vaccine Therapy in Patients With Non-Small Cell Lung Cancer PHASE1/PHASE2UNKNOWN
Histocompatibility Leukocyte Antigen (HLA)-A*2402 Restricted Peptide Vaccine Therapy in Patients With Gastric Cancer PHASE1/PHASE2COMPLETED
Histocompatibility Leukocyte Antigen (HLA)-A*0201 Restricted Peptide Vaccine Therapy in Patients With Esophageal Cancer PHASE1/PHASE2COMPLETED
Histocompatibility Leukocyte Antigen (HLA)-A*0201 Restricted Peptide Vaccine Therapy in Patients With Gastric Cancer PHASE1/PHASE2COMPLETED
Testing the Combination of MLN4924 (Pevonedistat), Carboplatin, and Paclitaxel in Patients With Advanced Non-small Cell Lung Cancer (NSCLC) Who Have Previously Been Treated With Immunotherapy PHASE2ACTIVE_NOT_RECRUITING
Combination of Chemoradiation Therapy and Epitope Peptide Vaccine Therapy in Treating Patients With Esophageal Cancer PHASE1UNKNOWN
Human Leukocyte Antigen (HLA) - A*2402 Restricted Peptide Vaccine Therapy in Patients With Advanced Esophageal Cancer PHASE1COMPLETED
Safety Study of Peptide Cancer Vaccine To Treat HLA-A*24-positive Advanced Non-small Cell Lung Cancer PHASE1COMPLETED
Safety Study of Multiple-Vaccine to Treat Metastatic Breast Cancer PHASE1COMPLETED
Human Leukocyte Antigen (HLA) - A*2402 Restricted Peptide Vaccine Therapy in Patients With Advanced Gastric Cancer PHASE1COMPLETED
Gemcitabine With Peptide Vaccine Therapy in Treating Patients With Bile Duct Cancer PHASE1SUSPENDED
Tolerability of Enteral NAC in Infants PHASE1NOT_YET_RECRUITING
Target of Suv420h1/2 in Hepatocytes nanRECRUITING
iPSC Neurons From Adult Survivors of Childhood Cancer Who Have Persistent Vincristine-Induced Neuropathy nanCOMPLETED
Chromosome 5Q Gene Variants and Asthma-Related Traits nanCOMPLETED
Genetic Analysis of Hereditary Disorders of Hearing and Balance nanCOMPLETED
Differential Gene Expression of Liver Tissue and Blood From Individuals With Chronic Viral Hepatitis nanUNKNOWN
Registry and Natural History Study for Early Onset Hereditary Spastic Paraplegia nanRECRUITING
Investigation of the Genetic Causes of Kallmann Syndrome and Reproductive Disorders nanCOMPLETED
Genetic Analysis of Keloids nanRECRUITING
Autophagy in Systemic Lupus Erythematosus nanUNKNOWN
PCD New Gene Discovery nanCOMPLETED
Genetic Epidemiology of Asthma in Costa Rica nanCOMPLETED
Immunogenetics of Visceral Leishmaniasis nanCOMPLETED
Hemochromatosis and Iron Overload Screening Study (HEIRS) nanCOMPLETED
Molecular Genetic Epidemiology of Endocardial Cushion Defects - SCOR in Pediatric Cardiovascular Disease nanCOMPLETED
Tecfidera Diffusion Tensor Imaging nanCOMPLETED
Linkage Study in Familial Pulmonary Fibrosis nanCOMPLETED
Sodium Transport: Genetics and Hypertension nanCOMPLETED

Related proteins — ESM-2 sequence neighbours (a KLHL20 binder may also engage these)

ProteinNameSimilarity
Q08DK3 — 1.000 Q08DK3 →
D3Z8N4 — 1.000 D3Z8N4 →
Q8VCK5 — 1.000 Q8VCK5 →
Q6DFF6 — 1.000 Q6DFF6 →
Q5ZKD9 — 1.000 Q5ZKD9 →
Q5R7B8 — 1.000 Q5R7B8 →
Q7QGL0 — 1.000 Q7QGL0 →
Q16RL8 — 1.000 Q16RL8 →
B3NDN0 — 0.999 B3NDN0 →
B4PD06 — 0.997 B4PD06 →
Q9VUU5 — 0.997 Q9VUU5 →
B4L0G9 — 0.996 B4L0G9 →
B4GRJ2 — 0.996 B4GRJ2 →
B0WWP2 — 0.996 B0WWP2 →
B4HIK1 — 0.996 B4HIK1 →
B4J045 — 0.995 B4J045 →
B4LIG6 — 0.993 B4LIG6 →
B3M9V8 — 0.993 B3M9V8 →
B4QLQ2 — 0.993 B4QLQ2 →
Q2M0J9 — 0.991 Q2M0J9 →
B4MXW3 — 0.986 B4MXW3 →
P28575 — 0.979 P28575 →
Q9P2G9 — 0.977 Q9P2G9 →
Q56A24 — 0.976 Q56A24 →
E9Q4F2 — 0.976 E9Q4F2 →
Q6TFL4 — 0.976 Q6TFL4 →
Q8BRG6 — 0.976 Q8BRG6 →
O94889 — 0.974 O94889 →
Q6TDP4 — 0.973 Q6TDP4 →
Q9Y573 — 0.973 Q9Y573 →