TNPO1

Transportin-1 · Q92973 · TNPO1 on Sugi Atlas →

0 patent compounds predicted against TNPO1, 0 high-confidence (nearest known ligand ≥ 0.5)

Top predicted compounds (top 20 by supporting neighbours, then confidence)

CompoundConfidenceSupporting neighbours

Clinical trials — most relevant to TNPO1 by text similarity (a relevance ranking, not an exhaustive list)

TrialPhaseStatus
Bovine Lactoferrin to Prevent and Cure Iron Deficiency and Iron Deficiency Anemia in Complicated Pregnancies PHASE4COMPLETED
Enhancing Effect on Tumour Apoptosis With the Use of Pentoxifylline in Patients With Hodgkin Lymphoma PHASE4UNKNOWN
Pharmacogenetic Treatment With Anti-Glutaminergic Agents for Comorbid PTSD & AUD PHASE3COMPLETED
Melpida: Recombinant Adeno-associated Virus (serotype 9) Encoding a Codon Optimized Human AP4M1 Transgene (hAP4M1opt) PHASE1/PHASE2RECRUITING
Brain as a Therapeutic and Research Target in Trigeminal Neuropathic Pain nanCOMPLETED
A Clinical Study on the Efficacy and Safety of Methotrexate (MTX) or Thiotepa (for MTX Intolerance) or Temozolomide (TMZ) Combined With Orelabrutinib and Selinexor in Relapsed/Refractory Primary or Secondary Central Nervous System Lymphoma(SELINA) nanRECRUITING
Molecular Genetic Epidemiology of Endocardial Cushion Defects - SCOR in Pediatric Cardiovascular Disease nanCOMPLETED
The Contribution of Optical Mapping to the Characterization of Chromosomal Rearrangements in Patients With Neurodevelopmental Disorders nanRECRUITING
Mapping Novel Disease Genes for Dilated Cardiomyopathy nanCOMPLETED
Pulmonary Hypertension--Mechanisms and Family Registry nanCOMPLETED
New Genes Involved in Molecular Etiology of Rett Syndrome Through DNA Microarray Comparative Genomic Hybridization nanCOMPLETED
The Influence of Genetic Variations in ELAPOR1 or ELAPOR2 on Insulin Secretion and Glucose Regulation in Humans nanUNKNOWN
Dilated Cardiomyopathy-Cardiac Magnetic Resonance (DCM-CMR) Ancillary Study nanACTIVE_NOT_RECRUITING
Molecular and Genetic Studies of Congenital Myopathies nanRECRUITING
Iron Overload in African Americans nanCOMPLETED
Natural History Evaluation of Charcot Marie Tooth Disease (CMT) Types CMT1B, CMT2A, CMT4A, CMT4C, and Others nanRECRUITING
Diagnosis of Primary Ciliary Dyskinesia nanCOMPLETED
Aswan Heart Centre - Egyptian Healthy Volunteers nanRECRUITING
Improvement of DIAgnostic and Phenotype-genotype Correlation Studies in Patients With MYOpathy Suspected of TITinopathy nanUNKNOWN
Biomarker for Sanfilippo Type A-B-C-D Disease (BioSanfilippo) nanWITHDRAWN
Genetic Analyses of Nonsyndromic and Syndromic Deafness in Pakistan nanENROLLING_BY_INVITATION
Brain P-gp and Inflammation in People With Epilepsy nanCOMPLETED
Universal Rare Gene Study: A Registry and Natural History Study of Retinal Dystrophies Associated With Rare Disease-Causing Genetic Variants nanRECRUITING
Gene Analysis of Parkinson's Disease nanCOMPLETED
Investigation of Copy Number Variations and Genetic Variants in POI nanRECRUITING
Muscle Tissue Bank for Muscular Dystrophy nanCOMPLETED
Evaluation of Possible Genes in Periodontal Diseases by Genetic Methods nanUNKNOWN
Exome Analysis in Hearing Impaired Patients nanUNKNOWN
PCD New Gene Discovery nanCOMPLETED
Roles of Some Non-classic Biomarkers in Pediatric Pneumonia nanUNKNOWN

Related proteins — ESM-2 sequence neighbours (a TNPO1 binder may also engage these)

ProteinNameSimilarity
Q3SYU7 1.000 Q3SYU7 →
Q8BFY9 1.000 Q8BFY9 →
Q99LG2 0.992 Q99LG2 →
O14787 0.992 O14787 →
KPNB1 Importin subunit beta-1 0.969 landscape →
P70168 0.968 P70168 →
P52296 0.965 P52296 →
XPO1 Exportin-1 0.952 landscape →
P52297 0.952 P52297 →
Q80U96 0.947 Q80U96 →
Q6P5F9 0.946 Q6P5F9 →
COPS2 COP9 signalosome complex subunit 2 0.941 landscape →
P61203 0.937 P61203 →
Q6IQT4 0.937 Q6IQT4 →
P61202 0.937 P61202 →
Q13888 0.935 Q13888 →
Q6IR75 0.935 Q6IR75 →
Q2TBV5 0.933 Q2TBV5 →
Q6P1K8 0.929 Q6P1K8 →
F1LTR1 0.925 F1LTR1 →
Q9JIB4 0.925 Q9JIB4 →
P17427 0.924 P17427 →
Q27HV0 0.924 Q27HV0 →
P18484 0.924 P18484 →
OGT UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110 kDa subunit 0.924 landscape →
Q9DCR2 0.923 Q9DCR2 →
AP3S1 AP-3 complex subunit sigma-1 0.923 landscape →
Q5SP67 0.923 Q5SP67 →
P56558 0.923 P56558 →
Q8CGY8 0.922 Q8CGY8 →