LETM1

Mitochondrial proton/calcium exchanger protein · O95202 · LETM1 on Sugi Atlas →

0 patent compounds predicted against LETM1, 0 high-confidence (nearest known ligand ≥ 0.5)

Top predicted compounds (top 20 by supporting neighbours, then confidence)

CompoundConfidenceSupporting neighbours

Clinical trials — most relevant to LETM1 by text similarity (a relevance ranking, not an exhaustive list)

TrialPhaseStatus
Clinical Evaluation of the Effect of Metformin in Sepsis PHASE3UNKNOWN
ONC201 in Recurrent/Refractory Metastatic Breast Cancer and Advanced Endometrial Carcinoma PHASE2COMPLETED
Trial of Oxaloacetate in ALS PHASE1COMPLETED
Calcium Electroporation for Head and Neck Cancer PHASE1UNKNOWN
A Phase I, Open-Labeled, Single-Arm, Dose Escalation, Clinical and Pharmacology Study of Dichloroacetate (DCA) in Patients With Recurrent and/or Metastatic Solid Tumours PHASE1COMPLETED
Influence of Morphine or Ketamine or Saline Applied During In-hospital Cardiopulmonary Resuscitation on Early Survival PHASE1UNKNOWN
Dynamics of Muscle Mitochondria in Type 2 Diabetes (DYNAMMO T2D) EARLY_PHASE1COMPLETED
Influence of Diabetic Neuropathy on Activation of Brown Adipose Tissue nanUNKNOWN
Predicting Pancreatic Necrosis Using mitDNA nanUNKNOWN
Mitochondrial Dysfunctions Driving Insulin Resistance nanCOMPLETED
Dynamics of Muscle Mitochondria in Type 2 Diabetes Exercise nanCOMPLETED
Exercise-mediated Rescue of Mitochondrial Dysfunctions Driving Insulin Resistance nanCOMPLETED
Effect of Hypothyroidism on Brown Adipose Tissue nanCOMPLETED
Tissue Sample Study for Mitochondrial Disorders nanENROLLING_BY_INVITATION
MERC Proteins in Saliva and GCF in Periodontal Disease (ELISA Study) nanCOMPLETED
Drug Repurposing for Mitochondrial Disorders Using iPSCs Derived Neural Cells nanRECRUITING
Recovery From 50 Eccentric Biceps Curls in Young, Untrained Men and Women nanCOMPLETED
Transgenerational Metabolic-Immune Biomarkers of Neurological and Neurodevelopmental Disorders nanRECRUITING
MOLECULAR REGULATION OF MUSCLE GLUCOSE METABOLISM (AIMS 2A, 2B, 3) nanUNKNOWN
Triheptanoin (UX007) to Treat Citrate Transporter Deficiency nanNO_LONGER_AVAILABLE
Skeletal Muscle Regeneration in Survivors of Critical Illness: How to Prevent Satellite Cell Failure? nanRECRUITING
Characteristics of Nondystrophic Myotonias nanCOMPLETED
Cerebrospinal Fluid Mitochondrial Biomarkers in Ischemic Stroke and Alzheimer Disease nanRECRUITING
The Natural History of Mitochondrial Diseases nanRECRUITING
Clinical Study of Hydroxytyrosol (HT) in Mitochondrial Diseases nanCOMPLETED
Effect of Branched Chain Amino Acids on Muscle nanCOMPLETED
Mitochondrial Dysfunction in Diabetes nanCOMPLETED
Multispectral Optoacoustic Tomography for Advanced Imaging of Centronuclear Myopathy nanRECRUITING
Measuring Protein Turnover in Humans Across the Lifespan by Metabolic Labeling With Deuterium Oxide nanRECRUITING
Cardiac Mitochondrial Function in Explanted Human Hearts nanUNKNOWN

Related proteins — ESM-2 sequence neighbours (a LETM1 binder may also engage these)

ProteinNameSimilarity
Q9Z2I0 1.000 Q9Z2I0 →
Q0VCA3 1.000 Q0VCA3 →
Q5XIN6 1.000 Q5XIN6 →
Q0VA06 0.999 Q0VA06 →
Q1LY46 0.998 Q1LY46 →
Q5ZK33 0.998 Q5ZK33 →
Q58CP9 0.982 Q58CP9 →
P91927 0.982 P91927 →
Q8IQ70 0.981 Q8IQ70 →
STIM1 Stromal interaction molecule 1 0.981 landscape →
P84903 0.980 P84903 →
Q9ERA6 0.980 Q9ERA6 →
Q5PQQ5 0.980 Q5PQQ5 →
Q66JD1 0.980 Q66JD1 →
Q9CQN1 0.980 Q9CQN1 →
P70302 0.980 P70302 →
Q9FG01 0.979 Q9FG01 →
Q7T0S7 0.979 Q7T0S7 →
A4UMC5 0.979 A4UMC5 →
Q8VCE1 0.979 Q8VCE1 →
Q29RR5 0.979 Q29RR5 →
Q498P2 0.979 Q498P2 →
Q1KKR9 0.979 Q1KKR9 →
Q5U2Y6 0.979 Q5U2Y6 →
Q3SYW6 0.979 Q3SYW6 →
D6WIX5 0.979 D6WIX5 →
Q1L987 0.979 Q1L987 →
Q5ZKI4 0.978 Q5ZKI4 →
Q7Z3E5 0.978 Q7Z3E5 →
NFKB1 Nuclear factor NF-kappa-B p105 subunit 0.978 landscape →