MKRN3

E3 ubiquitin-protein ligase makorin-3 · Q13064 · MKRN3 on Sugi Atlas →

0 patent compounds predicted against MKRN3, 0 high-confidence (nearest known ligand ≥ 0.5)

Top predicted compounds (top 20 by supporting neighbours, then confidence)

CompoundConfidenceSupporting neighbours

Clinical trials — most relevant to MKRN3 by text similarity (a relevance ranking, not an exhaustive list)

TrialPhaseStatus
Effects of Genistein Aglycone in Glucocorticoid Induced Osteoporosis PHASE2/PHASE3UNKNOWN
Treatment With HMG-COA Reductase Inhibitor of Growth and Bone Abnormalities in Children With Noonan Syndrome PHASE3COMPLETED
The G Protein-Coupled Receptor Kinase Type 2 Inhibitor Paroxetine as Adjunctive Therapy to Improve Insulin Sensitivity in Patients With Type 2 Diabetes Mellitus PHASE3UNKNOWN
Pembrolizumab (MK-3475) in MM Patients With Residual Disease PHASE2COMPLETED
A Phase 2 Study of Oral MKC-1 in Patients With Ovarian or Endometrial Cancer PHASE2COMPLETED
Temsirolimus and Sorafenib in Advanced Hepatocellular Carcinoma PHASE1COMPLETED
PS-341 and Radiation to Treat Advanced Cancer of the Head and Neck PHASE1COMPLETED
Novel Molecular Targets and Innovative Therapeutic Perspective in Medulloblastoma EARLY_PHASE1RECRUITING
Pre-Surgical Trial of the Combination of Metformin and Atorvastatin in Newly Diagnosed Operable Breast Cancer EARLY_PHASE1COMPLETED
COPENHAGEN Minipuberty Study nanUNKNOWN
Clinical Study of 68Ga-DOTA-BLP PET Imaging in Noninvasive Diagnosis of Malignant Tumors nanNOT_YET_RECRUITING
Differential Gene Expression of Liver Tissue and Blood From Individuals With Chronic Viral Hepatitis nanUNKNOWN
Autophagy in Systemic Lupus Erythematosus nanUNKNOWN
Regulation of Lymphocyte Anti-tumor Response in Metastatic Patients Treated With the mTOR Inhibitor Everolimus nanCOMPLETED
Genetic Variation in TRAF3IP2 (rs13190932) nanRECRUITING
Study of Metabolic Modifications in Children With Noonan Syndrome nanCOMPLETED
Characterization of New Candidate Genes in Cases of Human Inherited Thrombocytopenia (CATCH) nanCOMPLETED
SMYD3-Driven Metabolic Rewiring in Colorectal Liver Metastases nanNOT_YET_RECRUITING
Effect of Dietary Nitrate on Immobilization-induced Changes in Skeletal Muscle in Young Healthy Men nanRECRUITING
Investigation of Copy Number Variations and Genetic Variants in POI nanRECRUITING
Investigation of the Genetic Causes of Kallmann Syndrome and Reproductive Disorders nanCOMPLETED
Inherited Reproductive Disorders nanRECRUITING
Melanocortin Gene Expression in Lymphocytes of Polymyalgia Patients nanCOMPLETED
Changes in Skin Innervation of Neurologically Asymptomatic Type 2 Diabetic Patients: the Correlation With the Diabetic Parameters and Neurotrophins. nanUNKNOWN
Amplification of Zinc Finger Protein 217 Gene in Multiple Myeloma nanUNKNOWN
The Role of RING Ubiquitin Ligases in Biologic and Oncologic Processes in Tissues of Mesenchymal Origin nanUNKNOWN
Genetic Studies of Inflammatory Bowel Disease nanCOMPLETED
Genetics of Endocrine Tumours - Familial Isolated Pituitary Adenoma - FIPA nanRECRUITING
Nuclear Myosin VI - a Therapeutic Target in Breast Cancer nanUNKNOWN
Protein Intake and Step Reduction in Older Adults nanCOMPLETED

Related proteins — ESM-2 sequence neighbours (a MKRN3 binder may also engage these)

ProteinNameSimilarity
Q60764 0.987 Q60764 →
Q6GLD9 0.984 Q6GLD9 →
Q9QXP6 0.983 Q9QXP6 →
Q3U2S4 0.983 Q3U2S4 →
Q76N89 0.983 Q76N89 →
Q5RBA5 0.983 Q5RBA5 →
SQSTM1 Sequestosome-1 0.983 landscape →
Q2YDU3 0.982 Q2YDU3 →
Q9DD48 0.982 Q9DD48 →
Q80UE6 0.982 Q80UE6 →
O43900 0.982 O43900 →
Q9Y6A5 0.981 Q9Y6A5 →
Q9Z0E3 0.981 Q9Z0E3 →
Q9DDY9 0.981 Q9DDY9 →
Q9ERV1 0.981 Q9ERV1 →
D3YY23 0.980 D3YY23 →
Q9DFG8 0.980 Q9DFG8 →
O08623 0.980 O08623 →
Q9WTJ6 0.980 Q9WTJ6 →
Q9C0B0 0.980 Q9C0B0 →
Q8K4P8 0.980 Q8K4P8 →
Q8BY98 0.980 Q8BY98 →
Q1L8G6 0.980 Q1L8G6 →
Q640U0 0.979 Q640U0 →
Q8BL48 0.979 Q8BL48 →
Q9NQC1 0.979 Q9NQC1 →
Q8C0J6 0.979 Q8C0J6 →
Q8AXV5 0.979 Q8AXV5 →
Q8NBR6 0.979 Q8NBR6 →
P46686 0.979 P46686 →