MMS19

MMS19 nucleotide excision repair protein homolog · Q96T76 · MMS19 on Sugi Atlas →

0 patent compounds predicted against MMS19, 0 high-confidence (nearest known ligand ≥ 0.5)

Top predicted compounds (top 20 by supporting neighbours, then confidence)

CompoundConfidenceSupporting neighbours

Clinical trials — most relevant to MMS19 by text similarity (a relevance ranking, not an exhaustive list)

TrialPhaseStatus
A Phase II Study of Tegafur-Uracil as Maintenance Chemotherapy in Patients With Stage II of Colon Cancer PHASE4UNKNOWN
Phase II Study of Olaparib and Pembrolizumab in Advanced Melanoma With Homologous Recombination (HR) Mutation PHASE2UNKNOWN
Chlorambucil in Metastatic PDAC Patients Bearing a Germ Line DNA Defects Repair Mutations (SALE Trial) PHASE2UNKNOWN
Efficacy and Safety Study of Niraparib in Melanoma With Genetic Homologous Recombination (HR) Mutation PHASE2UNKNOWN
Olaparib Maintenance in Patients With MCRPC After Docetaxel Treatment Reaching Partial or Stable Response (IMANOL) PHASE2COMPLETED
A Phase 1/2 Trial SRA737 in Combination With Gemcitabine and Cisplatin or Gemcitabine Alone in Advanced Cancer Subjects PHASE1/PHASE2COMPLETED
Mobilization and Collection of Peripheral Blood Stem Cells in Patients With Fanconi Anemia Using G-CSF and AMD3100 PHASE1/PHASE2COMPLETED
Niraparib in Combination with Cabozantinib (XL184) in Patients with Advanced Urothelial Cancer (NICARAGUA) PHASE1/PHASE2COMPLETED
Phase II ABT-888 With Cyclophosphamide PHASE2COMPLETED
I/II Phase Study Evaluating M1774 in Combination With Fulvestrant in HR+ and HER2- Advanced Breast Cancers PHASE1/PHASE2NOT_YET_RECRUITING
The BARCODE 2 Study - The Use of Genetic Profiling to Guide Prostate Cancer Treatment PHASE2ACTIVE_NOT_RECRUITING
A Phase I Trial of SHR3162 in Subjects With Advanced Solid Tumors PHASE1COMPLETED
Veliparib (ABT-888), an Oral PARP Inhibitor, and VX-970, an ATR Inhibitor, in Combination With Cisplatin in People With Refractory Solid Tumors PHASE1COMPLETED
Safety Study of ABT-888 Plus Topotecan Hydrochloride to Treat Patients With Solid Tumors and Lymphomas PHASE1COMPLETED
A Study to Evaluate the Safety, Pharmacokinetics and Oral Bio Availability of Veliparib in Subjects With Solid Tumors PHASE1COMPLETED
A Phase I Study of ABT-888, an Oral Inhibitor of Poly(ADP-ribose) Polymerase and Temozolomide in Children With Recurrent/Refractory CNS Tumors PHASE1COMPLETED
A Proof of Concept Study for the DNA Repair Driven by the Mesenchymal Stem Cells in Critical COVID-19 Patients nanCOMPLETED
Hypofractionated Protontherapy in Chordomas and Chondrosarcomas of the Skull Base nanRECRUITING
Prospective Multicenter Registry Study to Assess the Frequency of Lynch Syndrome Among Patients With Colorectal Cancer nanRECRUITING
Study of Markers of Cosmic Radiation Exposure and Effect Among Flight Crews nanCOMPLETED
Application of Genetic Polymorphisms of DNA Repair in The Prediction of Prostate Cancer Susceptibility and Its Clinical Outcome nanUNKNOWN
Studying Tissue Samples From Patients With Stage II Colon Cancer Treated on Clinical Trial CLB-9581 nanCOMPLETED
Telomere Repair Gene Mutation in Inflammatory Bowel Disease nanCOMPLETED
Genetics of Prostate Cancer in Young Patients nanCOMPLETED
DNA Repair Genes and Outcomes in Patients With Stage III NSCLC nanUNKNOWN
Prognostic Biomarkers in Patients With Urothelial Carcinoma nanCOMPLETED
Endocrine Disruptors and Life STILe in Breast Cancer Development nanUNKNOWN
Thymidine Kinase 1 in Risk Assessment for Hereditary Breast /Ovarian Cancer nanUNKNOWN
DNA Damage & Repair Proteins In Patients With Atherosclerotic Coronary Artery Disease nanCOMPLETED
Genetic Information to Inform Treatment and Screening for Prostate Cancer, GIFTS Study nanENROLLING_BY_INVITATION

Related proteins — ESM-2 sequence neighbours (a MMS19 binder may also engage these)

ProteinNameSimilarity
Q9D071 1.000 Q9D071 →
E1BP36 0.998 E1BP36 →
Q8NDA8 0.994 Q8NDA8 →
Q0V9L1 0.993 Q0V9L1 →
Q6DCF2 0.991 Q6DCF2 →
E0CZ22 0.987 E0CZ22 →
Q9C0B7 0.987 Q9C0B7 →
TTI1 TELO2-interacting protein 1 homolog 0.986 landscape →
A8C756 0.985 A8C756 →
RRP12 RRP12-like protein 0.985 landscape →
Q91V83 0.985 Q91V83 →
Q9UJ98 0.984 Q9UJ98 →
Q9DC40 0.984 Q9DC40 →
Q6GPP1 0.984 Q6GPP1 →
E7FBU4 0.984 E7FBU4 →
Q8C3S2 0.984 Q8C3S2 →
Q86Y56 0.984 Q86Y56 →
Q8K2Z4 0.983 Q8K2Z4 →
A7E2Y6 0.983 A7E2Y6 →
TTI2 TELO2-interacting protein 2 0.982 landscape →
Q5ZKD5 0.982 Q5ZKD5 →
Q7TPV4 0.982 Q7TPV4 →
Q8BGV4 0.981 Q8BGV4 →
B9EJR8 0.981 B9EJR8 →
Q0P5H9 0.981 Q0P5H9 →
A0JMW2 0.980 A0JMW2 →
TELO2 Telomere length regulation protein TEL2 homolog 0.979 landscape →
Q9WV76 0.979 Q9WV76 →
Q9YHB5 0.979 Q9YHB5 →
NCAPD2 Condensin complex subunit 1 0.979 landscape →