Sugi Predict

Sugi Predict / Targets / MYO1B

MYO1B

Unconventional myosin-Ib · O43795 · MYO1B on Sugi Atlas →

0 patent compounds predicted against MYO1B, 0 high-confidence (nearest known ligand ≥ 0.5)

Top predicted compounds (top 20 by supporting neighbours, then confidence)

CompoundConfidenceSupporting neighbours

Clinical trials — most relevant to MYO1B by text similarity (a relevance ranking, not an exhaustive list)

TrialPhaseStatus
Combined N-of-1 Trials Mexiletine vs Placebo in Patients With Non-Dystrophic Myotonia (NDM) PHASE2COMPLETED
Evaluating MED2005 & Nitrostat Bioavailability PHASE1COMPLETED
Characteristics of Nondystrophic Myotonias nanCOMPLETED
Transcutaneous Functional Magnetic Muscle Stimulation in Critically Ill nanUNKNOWN
Contractile Cross Sectional Areas and Muscle Strength in Patients With Congenital Myopathies nanCOMPLETED
Genetic Testing in Primary Congenital Glaucoma Patients nanUNKNOWN
Molecular and Genetic Studies of Congenital Myopathies nanRECRUITING
Mapping of End Stage Renal Disease Genetic Susceptibility in African Americans by Admixture Linkage Disequilibrium nanCOMPLETED
Nuclear Myosin VI - a Therapeutic Target in Breast Cancer nanUNKNOWN
A Multicenter Phenotype-Genotype Analysis of LGMD Patients in China nanENROLLING_BY_INVITATION
Pediatric Evaluation and Registry for Liver Cholestasis in Canada nanRECRUITING
Phenotype - Genotype Correlation in a Sample of Egyptian Patients With Congenital Myopathies and Congenital Muscular Dystrophies nanRECRUITING
Registry of Unexplained Cardiac Arrest nanCOMPLETED
Phenotypic and Genotypic Identification and Characterization of MYH9-related Constitutional Thrombocytopenia nanCOMPLETED
Observational Study to Observe Variations of Gait Parameters in Patients With Neuromuscular Diseases nanRECRUITING
Natural History Study for Patients With Nemaline Myopathy in Belgium nanNOT_YET_RECRUITING
Arrhythmias in Myotonic Muscular Dystrophy nanCOMPLETED
Spinal Muscular Atrophy (SMA) Biomarkers Study in the Immediate Postnatal Period of Development nanCOMPLETED
Muscle Tissue Bank for Muscular Dystrophy nanCOMPLETED
Myotubular and Centronuclear Myopathy Patient Registry nanRECRUITING
MYO-SHARE: MYO-MRI in Neuromuscular Diseases nanENROLLING_BY_INVITATION
Non-Motor Features of Cervical Dystonia (CD) nanCOMPLETED
A Single Center Prospective Study in an Estimated 570 Patients Who Underwent Genetic Screening at UZ Brussel in the Context of a Primary Cardiac Arrhythmia. Patients Showing a Variant Class 3,4 or 5 in SCN4A or CLCN1 Will Undergo a Clinical and Electrophysiological Review After IC. nanNOT_YET_RECRUITING
Signs and Symptoms of Genetic Abnormalities Linked to Inherited Heart Disease nanCOMPLETED
Congenital Muscle Disease Study of Patient and Family Reported Medical Information nanRECRUITING
WiTNNess - TNNT1 Myopathy Natural History Study nanRECRUITING
Natural History of Photoreceptor Degeneration in USH1B: Clinical Parameters and Validation of Functional Vision Tests in MYO7A nanRECRUITING
Role of Ultrasound in Diagnosis of Muscle Diseases nanCOMPLETED
Molecular Profile of the Evolution of Inclusion Body Myositis nanCOMPLETED
Genetics of Pediatric-Onset Motor Neuron and Neuromuscular Diseases nanCOMPLETED

Related proteins — ESM-2 sequence neighbours (a MYO1B binder may also engage these)

ProteinNameSimilarity
P46735 — 1.000 P46735 →
Q05096 — 1.000 Q05096 →
Q9QYF3 — 0.983 Q9QYF3 →
Q99104 — 0.979 Q99104 →
Q9Y4I1 — 0.979 Q9Y4I1 →
Q02440 — 0.978 Q02440 →
Q9NQX4 — 0.975 Q9NQX4 →
P21271 — 0.972 P21271 →
P70569 — 0.971 P70569 →
Q9ULV0 — 0.970 Q9ULV0 →
E7EZG2 — 0.958 E7EZG2 →
Q13459 — 0.957 Q13459 →
Q1DLP2 — 0.955 Q1DLP2 →
Q27991 — 0.953 Q27991 →
A1C4A5 — 0.952 A1C4A5 →
Q9UM54 — 0.952 Q9UM54 →
Q9I8D1 — 0.952 Q9I8D1 →
E1BPK6 — 0.950 E1BPK6 →
Q0CEX5 — 0.950 Q0CEX5 →
Q2US45 — 0.950 Q2US45 →
B0Y9Q4 — 0.950 B0Y9Q4 →
Q64331 — 0.950 Q64331 →
MYH10 Myosin-10 0.950 landscape →
Q61879 — 0.949 Q61879 →
Q9Z2D1 — 0.949 Q9Z2D1 →
Q4WC55 — 0.948 Q4WC55 →
A1DBH2 — 0.948 A1DBH2 →
Q9QY06 — 0.947 Q9QY06 →
Q9JLT0 — 0.946 Q9JLT0 →
Q5ZIV1 — 0.946 Q5ZIV1 →